Willem M. de Vos

Research interests

Publications

• Akkermansia muciniphila: paradigm for next-generation beneficial microorganisms

  Nature Reviews Gastroenterology & Hepatology · 2022 · https://doi.org/10.1038/s41575-022-00631-9

• Gut microbiome and health: mechanistic insights

  Gut · 2022 · https://doi.org/10.1136/gutjnl-2021-326789

• Mediterranean diet intervention alters the gut microbiome in older people reducing frailty and improving health status: the NU-AGE 1-year dietary intervention across five European countries

  Gut · 2020 · https://doi.org/10.1136/gutjnl-2019-319654

• Supplementation with Akkermansia muciniphila in overweight and obese human volunteers: a proof-of-concept exploratory study

  Nature Medicine · 2019 · https://doi.org/10.1038/s41591-019-0495-2

• Improvement of Insulin Sensitivity after Lean Donor Feces in Metabolic Syndrome Is Driven by Baseline Intestinal Microbiota Composition

  Cell Metabolism · 2017 · 10.1016/j.cmet.2017.09.008

• The First Microbial Colonizers of the Human Gut: Composition, Activities, and Health Implications of the Infant Gut Microbiota

  Microbiology and Molecular Biology Reviews · 2017 · https://doi.org/10.1128/mmbr.00036-17

• Enterotypes in the landscape of gut microbial community composition

  Nature Microbiology · 2017 · 10.1038/s41564-017-0072-8

• European consensus conference on faecal microbiota transplantation in clinical practice

  Gut · 2017 · 10.1136/gutjnl-2016-313017

• Next-Generation Beneficial Microbes: The Case of Akkermansia muciniphila

  Frontiers in Microbiology · 2017 · 10.3389/fmicb.2017.01765

• A purified membrane protein from Akkermansia muciniphila or the pasteurized bacterium improves metabolism in obese and diabetic mice

  Nature Medicine · 2016 · 10.1038/nm.4236

• Akkermansia muciniphila and its role in regulating host functions

  Microbial Pathogenesis · 2016 · 10.1016/j.micpath.2016.02.005

• The gut microbiota plays a protective role in the host defence against pneumococcal pneumonia

  Gut · 2015 · 10.1136/gutjnl-2015-309728

• Fat, fibre and cancer risk in African Americans and rural Africans

  Nature Communications · 2015 · 10.1038/ncomms7342

• The first 1000 cultured species of the human gastrointestinal microbiota

  FEMS Microbiology Reviews · 2014 · 10.1111/1574-6976.12075

• Duodenal Infusion of Donor Feces for Recurrent Clostridium difficile

  New England Journal of Medicine · 2013 · https://doi.org/10.1056/nejmoa1205037

• Richness of human gut microbiome correlates with metabolic markers

  Nature · 2013 · https://doi.org/10.1038/nature12506

• Cross-talk between Akkermansia muciniphila and intestinal epithelium controls diet-induced obesity

  Proceedings of the National Academy of Sciences · 2013 · https://doi.org/10.1073/pnas.1219451110

• Transfer of Intestinal Microbiota From Lean Donors Increases Insulin Sensitivity in Individuals With Metabolic Syndrome

  Gastroenterology · 2012 · https://doi.org/10.1053/j.gastro.2012.06.031

• Responses of Gut Microbiota and Glucose and Lipid Metabolism to Prebiotics in Genetic Obese and Diet-Induced Leptin-Resistant Mice

  Diabetes · 2011 · 10.2337/db11-0227

• Enterotypes of the human gut microbiome

  Nature · 2011 · https://doi.org/10.1038/nature09944

• Global and Deep Molecular Analysis of Microbiota Signatures in Fecal Samples From Patients With Irritable Bowel Syndrome

  Gastroenterology · 2011 · 10.1053/j.gastro.2011.07.043

• Through Ageing, and Beyond: Gut Microbiota and Inflammatory Status in Seniors and Centenarians

  PLoS ONE · 2010 · 10.1371/journal.pone.0010667

• Comparative Analysis of Pyrosequencing and a Phylogenetic Microarray for Exploring Microbial Community Structures in the Human Distal Intestine

  PLoS ONE · 2009 · 10.1371/journal.pone.0006669

• Akkermansia muciniphila gen. nov., sp. nov., a human intestinal mucin-degrading bacterium

  INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY · 2004 · 10.1099/ijs.0.02873-0

• Complete genome sequence of Lactobacillus plantarum WCFS1

  Proceedings of the National Academy of Sciences · 2003 · 10.1073/pnas.0337704100

• Temperature Gradient Gel Electrophoresis Analysis of 16S rRNA from Human Fecal Samples Reveals Stable and Host-Specific Communities of Active Bacteria

  Applied and Environmental Microbiology · 1998 · 10.1128/aem.64.10.3854-3859.1998

Current projects

No projects listed.