Martti Färkkilâ

Research interests

Publications

• Author Correction: A genomic mutational constraint map using variation in 76,156 human genomes

  Nature · 2024 · https://doi.org/10.1038/s41586-024-07050-7

• FinnGen provides genetic insights from a well-phenotyped isolated population

  Nature · 2023 · https://doi.org/10.1038/s41586-022-05473-8

• A genomic mutational constraint map using variation in 76,156 human genomes

  Nature · 2023 · https://doi.org/10.1038/s41586-023-06045-0

• Author Correction: FinnGen provides genetic insights from a well-phenotyped isolated population

  Nature · 2023 · https://doi.org/10.1038/s41586-023-05837-8

• Global change in hepatitis C virus prevalence and cascade of care between 2015 and 2020: a modelling study

  ˜The œLancet. Gastroenterology & hepatology · 2022 · https://doi.org/10.1016/s2468-1253(21)00472-6

• FinnGen: Unique genetic insights from combining isolated population and national health register data

  medRxiv · 2022 · https://doi.org/10.1101/2022.03.03.22271360

• Landscape of multi-nucleotide variants in 125,748 human exomes and 15,708 genomes

  Nature Communications · 2020 · https://doi.org/10.1038/s41467-019-12438-5

• The mutational constraint spectrum quantified from variation in 141,456 humans

  Nature · 2020 · https://doi.org/10.1038/s41586-020-2308-7

• Transcript expression-aware annotation improves rare variant interpretation

  Nature · 2020 · https://doi.org/10.1038/s41586-020-2329-2

• Patient Age, Sex, and Inflammatory Bowel Disease Phenotype Associate With Course of Primary Sclerosing Cholangitis

  Gastroenterology · 2017 · https://doi.org/10.1053/j.gastro.2017.02.038

• Genome-wide association study of primary sclerosing cholangitis identifies new risk loci and quantifies the genetic relationship with inflammatory bowel disease

  Nature Genetics · 2016 · https://doi.org/10.1038/ng.3745

• Dense genotyping of immune-related disease regions identifies nine new risk loci for primary sclerosing cholangitis

  Nature Genetics · 2013 · https://doi.org/10.1038/ng.2616

• Ciclosporin versus infliximab in patients with severe ulcerative colitis refractory to intravenous steroids: a parallel, open-label randomised controlled trial

  The Lancet · 2012 · https://doi.org/10.1016/s0140-6736(12)61084-8

• Budesonide Induces Remission More Effectively Than Prednisone in a Controlled Trial of Patients With Autoimmune Hepatitis

  Gastroenterology · 2010 · https://doi.org/10.1053/j.gastro.2010.06.046

• Crohnʼs disease activity assessed by fecal calprotectin and lactoferrin: Correlation with Crohnʼs disease activity index and endoscopic findings

  Inflammatory Bowel Diseases · 2007 · https://doi.org/10.1002/ibd.20312

• A probiotic mixture alleviates symptoms in irritable bowel syndrome patients: a controlled 6‐month intervention

  Alimentary Pharmacology & Therapeutics · 2005 · https://doi.org/10.1111/j.1365-2036.2005.02579.x

• Debulking or biopsy of malignant glioma in elderly people – a randomised study

  Acta Neurochirurgica · 2003 · https://doi.org/10.1007/s00701-002-1030-6

Current projects

No projects listed.