Ahmed A. Ahmed

Research interests

Publications

• Subtraction-free and bisulfite-free specific sequencing of 5-methylcytosine and its oxidized derivatives at base resolution

  Nature Communications · 2021 · 10.1038/s41467-021-20920-2

• Promises and challenges of adoptive T-cell therapies for solid tumours

  British Journal of Cancer · 2021 · 10.1038/s41416-021-01353-6

• A dynamic CD2-rich compartment at the outer edge of the immunological synapse boosts and integrates signals

  Nature Immunology · 2020 · https://doi.org/10.1038/s41590-020-0770-x

• The Repertoire of Serous Ovarian Cancer Non-genetic Heterogeneity Revealed by Single-Cell Sequencing of Normal Fallopian Tube Epithelial Cells

  Cancer Cell · 2020 · 10.1016/j.ccell.2020.01.003

• Genome and epigenome engineering CRISPR toolkit for in vivo modulation of cis -regulatory interactions and gene expression in the chicken embryo

  Development · 2018 · 10.1242/dev.160333

• An evolving story of the metastatic voyage of ovarian cancer cells: cellular and molecular orchestration of the adipose-rich metastatic microenvironment

  Oncogene · 2018 · 10.1038/s41388-018-0637-x

• Salt-Inducible Kinase 2 Couples Ovarian Cancer Cell Metabolism with Survival at the Adipocyte-Rich Metastatic Niche

  Cancer Cell · 2016 · 10.1016/j.ccell.2016.06.020

• Rethinking ovarian cancer II: reducing mortality from high-grade serous ovarian cancer

  Nature reviews. Cancer · 2015 · https://doi.org/10.1038/nrc4019

• Decitabine and suberoylanilide hydroxamic acid (SAHA) inhibit growth of ovarian cancer cell lines and xenografts while inducing expression of imprinted tumor suppressor genes, apoptosis, G2/M arrest, and autophagy

  Cancer · 2011 · 10.1002/cncr.26073

• SIK2 Is a Centrosome Kinase Required for Bipolar Mitotic Spindle Formation that Provides a Potential Target for Therapy in Ovarian Cancer

  Cancer Cell · 2010 · 10.1016/j.ccr.2010.06.018

• Driver mutations in TP53 are ubiquitous in high grade serous carcinoma of the ovary

  The Journal of Pathology · 2010 · https://doi.org/10.1002/path.2696

• The Extracellular Matrix Protein TGFBI Induces Microtubule Stabilization and Sensitizes Ovarian Cancers to Paclitaxel

  Cancer Cell · 2007 · https://doi.org/10.1016/j.ccr.2007.11.014

• Regulators of Mitotic Arrest and Ceramide Metabolism Are Determinants of Sensitivity to Paclitaxel and Other Chemotherapeutic Drugs

  Cancer Cell · 2007 · 10.1016/j.ccr.2007.04.011

• High resolution melting for mutation scanning of TP53exons 5–8

  BMC Cancer · 2007 · 10.1186/1471-2407-7-168

• Differential expression of selected histone modifier genes in human solid cancers

  BMC Genomics · 2006 · https://doi.org/10.1186/1471-2164-7-90

• Molecular Classification and Molecular Forecasting of Breast Cancer: Ready for Clinical Application?

  Journal of Clinical Oncology · 2005 · https://doi.org/10.1200/jco.2005.03.3845

• Essential Role of the Prosurvival bcl-2 Homologue A1 in Mast Cell Survival After Allergic Activation

  The Journal of Experimental Medicine · 2001 · 10.1084/jem.194.11.1561

Current projects

No projects listed.