Alberto Mantovani

Research interests

Publications

• Macrophages as tools and targets in cancer therapy

  Nature Reviews Drug Discovery · 2022 · 10.1038/s41573-022-00520-5

• Neutrophil diversity and plasticity in tumour progression and therapy

  Nature reviews. Cancer · 2020 · 10.1038/s41568-020-0281-y

• Diversity, Mechanisms, and Significance of Macrophage Plasticity

  Annual Review of Pathology Mechanisms of Disease · 2019 · 10.1146/annurev-pathmechdis-012418-012718

• Chronic inflammation in the etiology of disease across the life span

  Nature Medicine · 2019 · https://doi.org/10.1038/s41591-019-0675-0

• A guiding map for inflammation

  Nature Immunology · 2017 · https://doi.org/10.1038/ni.3790

• Tumour-associated macrophages as treatment targets in oncology

  Nature Reviews Clinical Oncology · 2017 · 10.1038/nrclinonc.2016.217

• Macrophage Activation and Polarization: Nomenclature and Experimental Guidelines

  Immunity · 2014 · https://doi.org/10.1016/j.immuni.2014.06.008

• International Union of Basic and Clinical Pharmacology. LXXXIX. Update on the Extended Family of Chemokine Receptors and Introducing a New Nomenclature for Atypical Chemokine Receptors

  Pharmacological Reviews · 2013 · https://doi.org/10.1124/pr.113.007724

• The Interleukin-1 Family: Back to the Future

  Immunity · 2013 · 10.1016/j.immuni.2013.11.010

• Macrophage plasticity and polarization: in vivo veritas

  Journal of Clinical Investigation · 2012 · https://doi.org/10.1172/jci59643

• Macrophage plasticity and polarization in tissue repair and remodelling

  The Journal of Pathology · 2012 · 10.1002/path.4133

• Neutrophils in the activation and regulation of innate and adaptive immunity

  Nature reviews. Immunology · 2011 · 10.1038/nri3024

• Macrophage plasticity and interaction with lymphocyte subsets: cancer as a paradigm

  Nature Immunology · 2010 · 10.1038/ni.1937

• Macrophages, innate immunity and cancer: balance, tolerance, and diversity

  Current Opinion in Immunology · 2010 · 10.1016/j.coi.2010.01.009

• Cancer-related inflammation, the seventh hallmark of cancer: links to genetic instability

  Carcinogenesis · 2009 · 10.1093/carcin/bgp127

• Tumor-associated macrophages (TAM) as major players of the cancer-related inflammation

  Journal of Leukocyte Biology · 2009 · 10.1189/jlb.0609385

• Cancer-related inflammation

  Nature · 2008 · https://doi.org/10.1038/nature07205

• Macrophage polarization in tumour progression

  Seminars in Cancer Biology · 2008 · 10.1016/j.semcancer.2008.03.004

• Transcriptional Profiling of the Human Monocyte-to-Macrophage Differentiation and Polarization: New Molecules and Patterns of Gene Expression

  The Journal of Immunology · 2006 · 10.4049/jimmunol.177.10.7303

• Tumour-associated macrophages are a distinct M2 polarised population promoting tumour progression: Potential targets of anti-cancer therapy

  European Journal of Cancer · 2006 · 10.1016/j.ejca.2006.01.003

• Macrophage Polarization Comes of Age

  Immunity · 2005 · 10.1016/j.immuni.2005.10.001

• Smoldering and polarized inflammation in the initiation and promotion of malignant disease

  Cancer Cell · 2005 · 10.1016/j.ccr.2005.02.013

• The chemokine system in diverse forms of macrophage activation and polarization

  Trends in Immunology · 2004 · https://doi.org/10.1016/j.it.2004.09.015

• Macrophage polarization: tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes

  Trends in Immunology · 2002 · 10.1016/s1471-4906(02)02302-5

• Inflammation and cancer: back to Virchow?

  The Lancet · 2001 · https://doi.org/10.1016/s0140-6736(00)04046-0

• Differential Expression of Chemokine Receptors and Chemotactic Responsiveness of Type 1 T Helper Cells (Th1s) and Th2s

  The Journal of Experimental Medicine · 1998 · 10.1084/jem.187.1.129

• Migration of human monocytes in response to vascular endothelial growth factor (VEGF) is mediated via the VEGF receptor flt-1

  Blood · 1996 · 10.1182/blood.v87.8.3336.bloodjournal8783336

Current projects

No projects listed.