William Matsui

Research interests

Publications

• Anti-CD19 CAR T cells with high-dose melphalan and autologous stem cell transplantation for refractory multiple myeloma

  JCI Insight · 2018 · 10.1172/jci.insight.120505

• Cancer stem cell signaling pathways

  Medicine · 2016 · 10.1097/md.0000000000004765

• Outcomes of Nonmyeloablative HLA-Haploidentical Blood or Marrow Transplantation With High-Dose Post-Transplantation Cyclophosphamide in Older Adults

  Journal of Clinical Oncology · 2015 · 10.1200/jco.2014.60.4777

• Risk-stratified outcomes of nonmyeloablative HLA-haploidentical BMT with high-dose posttransplantation cyclophosphamide

  Blood · 2015 · 10.1182/blood-2015-01-623991

• Single-agent GVHD prophylaxis with posttransplantation cyclophosphamide after myeloablative, HLA-matched BMT for AML, ALL, and MDS

  Blood · 2014 · 10.1182/blood-2014-07-587477

• DCLK1 Marks a Morphologically Distinct Subpopulation of Cells With Stem Cell Properties in Preinvasive Pancreatic Cancer

  Gastroenterology · 2013 · 10.1053/j.gastro.2013.09.050

• Transient Low Doses of DNA-Demethylating Agents Exert Durable Antitumor Effects on Hematological and Epithelial Tumor Cells

  Cancer Cell · 2012 · https://doi.org/10.1016/j.ccr.2011.12.029

• A DNA hypermethylation module for the stem/progenitor cell signature of cancer

  Genome Research · 2012 · 10.1101/gr.131169.111

• Prognostic Significance of Tumorigenic Cells With Mesenchymal Features in Pancreatic Adenocarcinoma

  JNCI Journal of the National Cancer Institute · 2010 · 10.1093/jnci/djp535

• High-dose cyclophosphamide as single-agent, short-course prophylaxis of graft-versus-host disease

  Blood · 2010 · 10.1182/blood-2009-11-251595

• Tumor-Initiating Cells Are Rare in Many Human Tumors

  Cell stem cell · 2010 · 10.1016/j.stem.2010.08.009

• Hypoxia Increases the Expression of Stem-Cell Markers and Promotes Clonogenicity in Glioblastoma Neurospheres

  American Journal Of Pathology · 2010 · 10.2353/ajpath.2010.091021

• Targeting Hedgehog — a Cancer Stem Cell Pathway

  Clinical Cancer Research · 2010 · 10.1158/1078-0432.ccr-09-2846

• A direct pancreatic cancer xenograft model as a platform for cancer stem cell therapeutic development

  Molecular Cancer Therapeutics · 2009 · 10.1158/1535-7163.mct-08-0924

• Ligand-dependent Notch Signaling Is Involved in Tumor Initiation and Tumor Maintenance in Pancreatic Cancer

  Clinical Cancer Research · 2009 · 10.1158/1078-0432.ccr-08-2004

• Nonmyeloablative HLA-Haploidentical Bone Marrow Transplantation with High-Dose Posttransplantation Cyclophosphamide: Effect of HLA Disparity on Outcome

  Transplantation and Cellular Therapy · 2009 · 10.1016/j.bbmt.2009.11.011

• HLA-Haploidentical Bone Marrow Transplantation for Hematologic Malignancies Using Nonmyeloablative Conditioning and High-Dose, Posttransplantation Cyclophosphamide

  Transplantation and Cellular Therapy · 2008 · https://doi.org/10.1016/j.bbmt.2008.03.005

• Clonogenic Multiple Myeloma Progenitors, Stem Cell Properties, and Drug Resistance

  Cancer Research · 2008 · 10.1158/0008-5472.can-07-3096

• An orally bioavailable small-molecule inhibitor of Hedgehog signaling inhibits tumor initiation and metastasis in pancreatic cancer

  Molecular Cancer Therapeutics · 2008 · 10.1158/1535-7163.mct-08-0573

• Hedgehog signaling maintains a tumor stem cell compartment in multiple myeloma

  Proceedings of the National Academy of Sciences · 2007 · 10.1073/pnas.0611682104

• Cyclopamine-Mediated Hedgehog Pathway Inhibition Depletes Stem-Like Cancer Cells in Glioblastoma

  Stem Cells · 2007 · 10.1634/stemcells.2007-0166

• Blockade of Hedgehog Signaling Inhibits Pancreatic Cancer Invasion and Metastases: A New Paradigm for Combination Therapy in Solid Cancers

  Cancer Research · 2007 · 10.1158/0008-5472.can-06-3281

• Notch Pathway Inhibition Depletes Stem-like Cells and Blocks Engraftment in Embryonal Brain Tumors

  Cancer Research · 2006 · 10.1158/0008-5472.can-06-0858

• Association of Foxp3 regulatory gene expression with graft-versus-host disease

  Blood · 2004 · 10.1182/blood-2004-03-1040

• Characterization of clonogenic multiple myeloma cells

  Blood · 2003 · 10.1182/blood-2003-09-3064

Current projects

No projects listed.