Seppo Ylä‐Herttuala

Research interests

Publications

• Microanatomy of the Human Atherosclerotic Plaque by Single-Cell Transcriptomics

  Circulation Research · 2020 · 10.1161/circresaha.120.316770

• Somatic Activating KRAS Mutations in Arteriovenous Malformations of the Brain

  New England Journal of Medicine · 2018 · 10.1056/nejmoa1709449

• Oxidized phospholipids are proinflammatory and proatherogenic in hypercholesterolaemic mice

  Nature · 2018 · 10.1038/s41586-018-0198-8

• Consensus guidelines for the use and interpretation of angiogenesis assays

  Angiogenesis · 2018 · 10.1007/s10456-018-9613-x

• History of gene therapy

  Gene · 2013 · 10.1016/j.gene.2013.03.137

• Vascular endothelial growth factor B controls endothelial fatty acid uptake

  Nature · 2010 · 10.1038/nature08945

• Blocking VEGFR-3 suppresses angiogenic sprouting and vascular network formation

  Nature · 2008 · https://doi.org/10.1038/nature07083

• Stabilization of HIF-1α is critical to improve wound healing in diabetic mice

  Proceedings of the National Academy of Sciences · 2008 · 10.1073/pnas.0805230105

• Vascular Endothelial Growth Factors

  Journal of the American College of Cardiology · 2007 · 10.1016/j.jacc.2006.09.053

• Biology of vascular endothelial growth factors

  FEBS Letters · 2006 · 10.1016/j.febslet.2006.03.087

• Pathogenesis of persistent lymphatic vessel hyperplasia in chronic airway inflammation

  Journal of Clinical Investigation · 2005 · 10.1172/jci22037

• Pathogenesis of persistent lymphatic vessel hyperplasia in chronic airway inflammation

  Journal of Clinical Investigation · 2005 · 10.1172/jci200522037

• Defective valves and abnormal mural cell recruitment underlie lymphatic vascular failure in lymphedema distichiasis

  Nature Medicine · 2004 · 10.1038/nm1094

• Safety and Feasibility of Catheter-Based Local Intracoronary Vascular Endothelial Growth Factor Gene Transfer in the Prevention of Postangioplasty and In-Stent Restenosis and in the Treatment of Chronic Myocardial Ischemia

  Circulation · 2003 · 10.1161/01.cir.0000070540.80780.92

• Suppression of Tumor Lymphangiogenesis and Lymph Node Metastasis by Blocking Vascular Endothelial Growth Factor Receptor 3 Signaling

  JNCI Journal of the National Cancer Institute · 2002 · 10.1093/jnci/94.11.819

• Inhibition of lymphangiogenesis with resulting lymphedema in transgenic mice expressing soluble VEGF receptor-3

  Nature Medicine · 2001 · 10.1038/84651

• A model for gene therapy of human hereditary lymphedema

  Proceedings of the National Academy of Sciences · 2001 · 10.1073/pnas.221449198

• Vascular endothelial growth factor C promotes tumor lymphangiogenesis and intralymphatic tumor growth.

  PubMed · 2001

• Experimental liver cirrhosis induced by alcohol and iron.

  Journal of Clinical Investigation · 1995 · 10.1172/jci118077

• Rabbit and human atherosclerotic lesions contain IgG that recognizes epitopes of oxidized LDL.

  Arteriosclerosis and Thrombosis A Journal of Vascular Biology · 1994 · 10.1161/01.atv.14.1.32

• Autoantibody against oxidised LDL and progression of carotid atherosclerosis

  The Lancet · 1992 · https://doi.org/10.1016/0140-6736(92)90926-t

• Expression of monocyte chemoattractant protein 1 in macrophage-rich areas of human and rabbit atherosclerotic lesions.

  Proceedings of the National Academy of Sciences · 1991 · https://doi.org/10.1073/pnas.88.12.5252

• Antisera and monoclonal antibodies specific for epitopes generated during oxidative modification of low density lipoprotein.

  Arteriosclerosis An Official Journal of the American Heart Association Inc · 1990 · 10.1161/01.atv.10.3.325

• Low density lipoprotein undergoes oxidative modification in vivo.

  Proceedings of the National Academy of Sciences · 1989 · https://doi.org/10.1073/pnas.86.4.1372

• Evidence for the presence of oxidatively modified low density lipoprotein in atherosclerotic lesions of rabbit and man.

  Journal of Clinical Investigation · 1989 · 10.1172/jci114271

Current projects

No projects listed.