Yoshihiro Kawaoka

Research interests

Publications

• SARS-CoV-2 Omicron virus causes attenuated disease in mice and hamsters

  Nature · 2022 · https://doi.org/10.1038/s41586-022-04441-6

• An infectious SARS-CoV-2 B.1.1.529 Omicron virus escapes neutralization by therapeutic monoclonal antibodies

  Nature Medicine · 2022 · 10.1038/s41591-021-01678-y

• Broadly neutralizing antibodies overcome SARS-CoV-2 Omicron antigenic shift

  Nature · 2021 · https://doi.org/10.1038/s41586-021-04386-2

• Enhanced fusogenicity and pathogenicity of SARS-CoV-2 Delta P681R mutation

  Nature · 2021 · 10.1038/s41586-021-04266-9

• SARS-CoV-2 D614G variant exhibits efficient replication ex vivo and transmission in vivo

  Science · 2020 · 10.1126/science.abe8499

• Syrian hamsters as a small animal model for SARS-CoV-2 infection and countermeasure development

  Proceedings of the National Academy of Sciences · 2020 · 10.1073/pnas.2009799117

• Experimental adaptation of an influenza H5 HA confers respiratory droplet transmission to a reassortant H5 HA/H1N1 virus in ferrets

  Nature · 2012 · https://doi.org/10.1038/nature10831

• In vitro and in vivo characterization of new swine-origin H1N1 influenza viruses

  Nature · 2009 · 10.1038/nature08260

• Emergence and pandemic potential of swine-origin H1N1 influenza virus

  Nature · 2009 · https://doi.org/10.1038/nature08157

• Single-Reaction Genomic Amplification Accelerates Sequencing and Vaccine Production for Classical and Swine Origin Human Influenza A Viruses

  Journal of Virology · 2009 · 10.1128/jvi.01109-09

• Aberrant innate immune response in lethal infection of macaques with the 1918 influenza virus

  Nature · 2007 · 10.1038/nature05495

• Haemagglutinin mutations responsible for the binding of H5N1 influenza A viruses to human-type receptors

  Nature · 2006 · 10.1038/nature05264

• Influenza virus receptors in the human airway

  Nature · 2006 · 10.1038/440435a

• Influenza: lessons from past pandemics, warnings from current incidents

  Nature Reviews Microbiology · 2005 · 10.1038/nrmicro1208

• Isolation of drug-resistant H5N1 virus

  Nature · 2005 · https://doi.org/10.1038/4371108a

• Resistant influenza A viruses in children treated with oseltamivir: descriptive study

  The Lancet · 2004 · 10.1016/s0140-6736(04)16934-1

• Molecular Basis for High Virulence of Hong Kong H5N1 Influenza A Viruses

  Science · 2001 · 10.1126/science.1062882

• A DNA transfection system for generation of influenza A virus from eight plasmids

  Proceedings of the National Academy of Sciences · 2000 · 10.1073/pnas.100133697

• Early Alterations of the Receptor-Binding Properties of H1, H2, and H3 Avian Influenza Virus Hemagglutinins after Their Introduction into Mammals

  Journal of Virology · 2000 · 10.1128/jvi.74.18.8502-8512.2000

• Generation of influenza A viruses entirely from cloned cDNAs

  Proceedings of the National Academy of Sciences · 1999 · 10.1073/pnas.96.16.9345

• The Surface Glycoproteins of H5 Influenza Viruses Isolated from Humans, Chickens, and Wild Aquatic Birds Have Distinguishable Properties

  Journal of Virology · 1999 · 10.1128/jvi.73.2.1146-1155.1999

• Molecular Basis for the Generation in Pigs of Influenza A Viruses with Pandemic Potential

  Journal of Virology · 1998 · 10.1128/jvi.72.9.7367-7373.1998

• Evolution and ecology of influenza A viruses.

  Microbiological Reviews · 1992 · 10.1128/mmbr.56.1.152-179.1992

• Evolution and ecology of influenza A viruses

  Microbiological Reviews · 1992 · 10.1128/mr.56.1.152-179.1992

• Avian-to-human transmission of the PB1 gene of influenza A viruses in the 1957 and 1968 pandemics

  Journal of Virology · 1989 · 10.1128/jvi.63.11.4603-4608.1989

Current projects

No projects listed.