Christian Happi

Research interests

Publications

• New nomenclature for mpox (monkeypox) and monkeypox virus clades

  The Lancet Infectious Diseases · 2023 · https://doi.org/10.1016/s1473-3099(23)00055-5

• Multiplexed CRISPR-based microfluidic platform for clinical testing of respiratory viruses and identification of SARS-CoV-2 variants

  Nature Medicine · 2022 · https://doi.org/10.1038/s41591-022-01734-1

• Urgent need for a non-discriminatory and non-stigmatizing nomenclature for monkeypox virus

  PLoS Biology · 2022 · https://doi.org/10.1371/journal.pbio.3001769

• Simplified Cas13-based assays for the fast identification of SARS-CoV-2 and its variants

  Nature Biomedical Engineering · 2022 · https://doi.org/10.1038/s41551-022-00889-z

• Deployable CRISPR-Cas13a diagnostic tools to detect and report Ebola and Lassa virus cases in real-time

  Nature Communications · 2020 · https://doi.org/10.1038/s41467-020-17994-9

• Streamlined inactivation, amplification, and Cas13-based detection of SARS-CoV-2

  Nature Communications · 2020 · https://doi.org/10.1038/s41467-020-19097-x

• Capturing sequence diversity in metagenomes with comprehensive and scalable probe design

  Nature Biotechnology · 2019 · https://doi.org/10.1038/s41587-018-0006-x

• Genomic Analysis of Lassa Virus during an Increase in Cases in Nigeria in 2018

  New England Journal of Medicine · 2018 · https://doi.org/10.1056/nejmoa1804498

• Reemergence of Human Monkeypox in Nigeria, 2017

  Emerging infectious diseases · 2018 · https://doi.org/10.3201/eid2406.180017

• Virus genomes reveal factors that spread and sustained the Ebola epidemic

  Nature · 2017 · https://doi.org/10.1038/nature22040

• Most neutralizing human monoclonal antibodies target novel epitopes requiring both Lassa virus glycoprotein subunits

  Nature Communications · 2016 · https://doi.org/10.1038/ncomms11544

• Clinical Sequencing Uncovers Origins and Evolution of Lassa Virus

  Cell · 2015 · https://doi.org/10.1016/j.cell.2015.07.020

• Ebola Virus Epidemiology, Transmission, and Evolution during Seven Months in Sierra Leone

  Cell · 2015 · https://doi.org/10.1016/j.cell.2015.06.007

• Clinical Illness and Outcomes in Patients with Ebola in Sierra Leone

  New England Journal of Medicine · 2014 · https://doi.org/10.1056/nejmoa1411680

• Genomic surveillance elucidates Ebola virus origin and transmission during the 2014 outbreak

  Science · 2014 · https://doi.org/10.1126/science.1259657

• Lassa Fever in Post-Conflict Sierra Leone

  PLoS neglected tropical diseases · 2014 · https://doi.org/10.1371/journal.pntd.0002748

Current projects

No projects listed.