Heng Li

Research interests

Publications

• The Human Pangenome Project: a global resource to map genomic diversity

  Nature · 2022 · https://doi.org/10.1038/s41586-022-04601-8

• Haplotype-resolved assembly of diploid genomes without parental data

  Nature Biotechnology · 2022 · https://doi.org/10.1038/s41587-022-01261-x

• The complete sequence of a human genome

  Science · 2022 · https://doi.org/10.1126/science.abj6987

• Twelve years of SAMtools and BCFtools

  GigaScience · 2021 · https://doi.org/10.1093/gigascience/giab008

• New strategies to improve minimap2 alignment accuracy

  Bioinformatics · 2021 · 10.1093/bioinformatics/btab705

• Efficient Architecture-Aware Acceleration of BWA-MEM for Multicore Systems

  Journal · 2019 · 10.1109/ipdps.2019.00041

• Fast and accurate long-read assembly with wtdbg2

  Nature Methods · 2019 · https://doi.org/10.1038/s41592-019-0669-3

• Accurate circular consensus long-read sequencing improves variant detection and assembly of a human genome

  Nature Biotechnology · 2019 · 10.1038/s41587-019-0217-9

• Automatic Pixel‐Level Crack Detection and Measurement Using Fully Convolutional Network

  Computer-Aided Civil and Infrastructure Engineering · 2018 · https://doi.org/10.1111/mice.12412

• Minimap2: pairwise alignment for nucleotide sequences

  Bioinformatics · 2018 · https://doi.org/10.1093/bioinformatics/bty191

• Evaluation of GRCh38 and de novo haploid genome assemblies demonstrates the enduring quality of the reference assembly

  Genome Research · 2017 · 10.1101/gr.213611.116

• Minimap and miniasm: fast mapping and de novo assembly for noisy long sequences

  Bioinformatics · 2016 · 10.1093/bioinformatics/btw152

• The Simons Genome Diversity Project: 300 genomes from 142 diverse populations

  Nature · 2016 · 10.1038/nature18964

• Aligning sequence reads, clone sequences and assembly con*gs with BWA-MEM

  arXiv (Cornell University) · 2014 · 10.6084/m9.figshare.963153.v1

• Ancient human genomes suggest three ancestral populations for present-day Europeans

  Nature · 2014 · 10.1038/nature13673

• The complete genome sequence of a Neanderthal from the Altai Mountains

  Nature · 2013 · 10.1038/nature12886

• Great ape genetic diversity and population history

  Nature · 2013 · 10.1038/nature12228

• A High-Coverage Genome Sequence from an Archaic Denisovan Individual

  Science · 2012 · 10.1126/science.1224344

• Inference of human population history from individual whole-genome sequences

  Nature · 2011 · 10.1038/nature10231

• A statistical framework for SNP calling, mutation discovery, association mapping and population genetical parameter estimation from sequencing data

  Bioinformatics · 2011 · 10.1093/bioinformatics/btr509

• Fast and accurate long-read alignment with Burrows–Wheeler transform

  Bioinformatics · 2010 · https://doi.org/10.1093/bioinformatics/btp698

• Genetic history of an archaic hominin group from Denisova Cave in Siberia

  Nature · 2010 · 10.1038/nature09710

• A Draft Sequence of the Neandertal Genome

  Science · 2010 · 10.1126/science.1188021

• The Sequence Alignment/Map format and SAMtools

  Bioinformatics · 2009 · https://doi.org/10.1093/bioinformatics/btp352

• Fast and accurate short read alignment with Burrows–Wheeler transform

  Bioinformatics · 2009 · https://doi.org/10.1093/bioinformatics/btp324

• The sequence and de novo assembly of the giant panda genome

  Nature · 2009 · 10.1038/nature08696

• The diploid genome sequence of an Asian individual

  Nature · 2008 · 10.1038/nature07484

• Mapping short DNA sequencing reads and calling variants using mapping quality scores

  Genome Research · 2008 · 10.1101/gr.078212.108

• Accurate whole human genome sequencing using reversible terminator chemistry

  Nature · 2008 · 10.1038/nature07517

• EnsemblCompara GeneTrees: Complete, duplication-aware phylogenetic trees in vertebrates

  Genome Research · 2008 · 10.1101/gr.073585.107

• Identification of somatically acquired rearrangements in cancer using genome-wide massively parallel paired-end sequencing

  Nature Genetics · 2008 · 10.1038/ng.128

Current projects

No projects listed.