Joseph E. Powell

Research interests

Publications

• An integrated cell atlas of the lung in health and disease

  Nature Medicine · 2023 · https://doi.org/10.1038/s41591-023-02327-2

• Single-cell eQTL mapping identifies cell type–specific genetic control of autoimmune disease

  Science · 2022 · https://doi.org/10.1126/science.abf3041

• Identification of 371 genetic variants for age at first sex and birth linked to externalising behaviour

  Nature Human Behaviour · 2021 · https://doi.org/10.1038/s41562-021-01135-3

• A single-cell and spatially resolved atlas of human breast cancers

  Nature Genetics · 2021 · https://doi.org/10.1038/s41588-021-00911-1

• SARS-CoV-2 Receptor ACE2 Is an Interferon-Stimulated Gene in Human Airway Epithelial Cells and Is Detected in Specific Cell Subsets across Tissues

  Cell · 2020 · https://doi.org/10.1016/j.cell.2020.04.035

• Stromal cell diversity associated with immune evasion in human triple‐negative breast cancer

  The EMBO Journal · 2020 · https://doi.org/10.15252/embj.2019104063

• scPred: accurate supervised method for cell-type classification from single-cell RNA-seq data

  Genome biology · 2019 · https://doi.org/10.1186/s13059-019-1862-5

• Mendelian randomization integrating GWAS and eQTL data reveals genetic determinants of complex and clinical traits

  Nature Communications · 2019 · https://doi.org/10.1038/s41467-019-10936-0

• Unraveling the polygenic architecture of complex traits using blood eQTL metaanalysis

  bioRxiv (Cold Spring Harbor Laboratory) · 2018 · https://doi.org/10.1101/447367

• Genome-wide association study of intraocular pressure uncovers new pathways to glaucoma

  Nature Genetics · 2018 · https://doi.org/10.1038/s41588-018-0176-y

• Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes

  Nature Communications · 2018 · https://doi.org/10.1038/s41467-018-04951-w

• Identifying gene targets for brain-related traits using transcriptomic and methylomic data from blood

  Nature Communications · 2018 · https://doi.org/10.1038/s41467-018-04558-1

• Integration of summary data from GWAS and eQTL studies predicts complex trait gene targets

  Nature Genetics · 2016 · 10.1038/ng.3538

• The transcriptional landscape of age in human peripheral blood

  Nature Communications · 2015 · https://doi.org/10.1038/ncomms9570

• Population genetic differentiation of height and body mass index across Europe

  Nature Genetics · 2015 · https://doi.org/10.1038/ng.3401

• Systematic identification of trans eQTLs as putative drivers of known disease associations

  Nature Genetics · 2013 · https://doi.org/10.1038/ng.2756

• FTO genotype is associated with phenotypic variability of body mass index

  Nature · 2012 · https://doi.org/10.1038/nature11401

Current projects

No projects listed.