Luca Scorrano

Research interests

Publications

• Dietary spermidine improves cognitive function

  Cell Reports · 2021 · https://doi.org/10.1016/j.celrep.2021.108985

• Autophagy in major human diseases

  The EMBO Journal · 2021 · https://doi.org/10.15252/embj.2021108863

• The cell biology of mitochondrial membrane dynamics

  Nature Reviews Molecular Cell Biology · 2020 · https://doi.org/10.1038/s41580-020-0210-7

• Coming together to define membrane contact sites

  Nature Communications · 2019 · https://doi.org/10.1038/s41467-019-09253-3

• The cristae modulator Optic atrophy 1 requires mitochondrial ATP synthase oligomers to safeguard mitochondrial function

  Nature Communications · 2018 · https://doi.org/10.1038/s41467-018-05655-x

• Molecular definitions of autophagy and related processes

  The EMBO Journal · 2017 · https://doi.org/10.15252/embj.201796697

• Cardioprotection and lifespan extension by the natural polyamine spermidine

  Nature Medicine · 2016 · https://doi.org/10.1038/nm.4222

• Interplay between hepatic mitochondria-associated membranes, lipid metabolism and caveolin-1 in mice

  Scientific Reports · 2016 · https://doi.org/10.1038/srep27351

• Optic Atrophy 1 Is Epistatic to the Core MICOS Component MIC60 in Mitochondrial Cristae Shape Control

  Cell Reports · 2016 · https://doi.org/10.1016/j.celrep.2016.11.049

• Mitochondrial Cristae Shape Determines Respiratory Chain Supercomplexes Assembly and Respiratory Efficiency

  Cell · 2013 · https://doi.org/10.1016/j.cell.2013.08.032

• During autophagy mitochondria elongate, are spared from degradation and sustain cell viability

  Nature Cell Biology · 2011 · https://doi.org/10.1038/ncb2220

• Guidelines for the use and interpretation of assays for monitoring cell death in higher eukaryotes

  Cell Death and Differentiation · 2009 · https://doi.org/10.1038/cdd.2009.44

• Mitofusin 2 tethers endoplasmic reticulum to mitochondria

  Nature · 2008 · https://doi.org/10.1038/nature07534

• Dephosphorylation by calcineurin regulates translocation of Drp1 to mitochondria

  Proceedings of the National Academy of Sciences · 2008 · https://doi.org/10.1073/pnas.0808249105

• Organelle isolation: functional mitochondria from mouse liver, muscle and cultured filroblasts

  Nature Protocols · 2007 · https://doi.org/10.1038/nprot.2006.478

• OPA1 Controls Apoptotic Cristae Remodeling Independently from Mitochondrial Fusion

  Cell · 2006 · https://doi.org/10.1016/j.cell.2006.06.025

• OPA1 requires mitofusin 1 to promote mitochondrial fusion

  Proceedings of the National Academy of Sciences · 2004 · https://doi.org/10.1073/pnas.0407043101

• BAX and BAK Regulation of Endoplasmic Reticulum Ca 2+ : A Control Point for Apoptosis

  Science · 2003 · https://doi.org/10.1126/science.1081208

Current projects

No projects listed.