Rosario Rizzuto

Research interests

Publications

• Coming together to define membrane contact sites

  Nature Communications · 2019 · https://doi.org/10.1038/s41467-019-09253-3

• Calcium at the Center of Cell Signaling: Interplay between Endoplasmic Reticulum, Mitochondria, and Lysosomes

  Trends in Biochemical Sciences · 2016 · 10.1016/j.tibs.2016.09.001

• Lysosomal calcium signalling regulates autophagy through calcineurin and TFEB

  Nature Cell Biology · 2015 · https://doi.org/10.1038/ncb3114

• MICU1 and MICU2 Finely Tune the Mitochondrial Ca2+ Uniporter by Exerting Opposite Effects on MCU Activity

  Molecular Cell · 2014 · 10.1016/j.molcel.2014.01.013

• Essential versus accessory aspects of cell death: recommendations of the NCCD 2015

  Cell Death and Differentiation · 2014 · https://doi.org/10.1038/cdd.2014.137

• PERK is required at the ER-mitochondrial contact sites to convey apoptosis after ROS-based ER stress

  Cell Death and Differentiation · 2012 · https://doi.org/10.1038/cdd.2012.74

• Mitochondria as sensors and regulators of calcium signalling

  Nature Reviews Molecular Cell Biology · 2012 · https://doi.org/10.1038/nrm3412

• A forty-kilodalton protein of the inner membrane is the mitochondrial calcium uniporter

  Nature · 2011 · 10.1038/nature10230

• MAM: more than just a housekeeper

  Trends in Cell Biology · 2009 · 10.1016/j.tcb.2008.12.002

• Guidelines for the use and interpretation of assays for monitoring cell death in higher eukaryotes

  Cell Death and Differentiation · 2009 · 10.1038/cdd.2009.44

• Regulation of autophagy by cytoplasmic p53

  Nature Cell Biology · 2008 · 10.1038/ncb1730

• Bidirectional Ca 2+ -dependent control of mitochondrial dynamics by the Miro GTPase

  Proceedings of the National Academy of Sciences · 2008 · 10.1073/pnas.0808953105

• Calcium and apoptosis: ER-mitochondria Ca2+ transfer in the control of apoptosis

  Oncogene · 2008 · 10.1038/onc.2008.308

• Control of Macroautophagy by Calcium, Calmodulin-Dependent Kinase Kinase-β, and Bcl-2

  Molecular Cell · 2007 · 10.1016/j.molcel.2006.12.009

• Chaperone-mediated coupling of endoplasmic reticulum and mitochondrial Ca2+ channels

  The Journal of Cell Biology · 2006 · 10.1083/jcb.200608073

• Cleavage of the Plasma Membrane Na+/Ca2+ Exchanger in Excitotoxicity

  Cell · 2005 · 10.1016/j.cell.2004.11.049

• Microdomains of Intracellular Ca2+: Molecular Determinants and Functional Consequences

  Physiological Reviews · 2005 · 10.1152/physrev.00004.2005

• Electron Transfer between Cytochrome c and p66Shc Generates Reactive Oxygen Species that Trigger Mitochondrial Apoptosis

  Cell · 2005 · 10.1016/j.cell.2005.05.011

• Mitochondria as all‐round players of the calcium game

  The Journal of Physiology · 2000 · 10.1111/j.1469-7793.2000.00037.x

• Regulation of mitochondrial ATP synthesis by calcium: Evidence for a long-term metabolic priming

  Proceedings of the National Academy of Sciences · 1999 · 10.1073/pnas.96.24.13807

• Close Contacts with the Endoplasmic Reticulum as Determinants of Mitochondrial Ca 2+ Responses

  Science · 1998 · 10.1126/science.280.5370.1763

• Molecular and cellular physiology of intracellular calcium stores

  Physiological Reviews · 1994 · 10.1152/physrev.1994.74.3.595

• Microdomains with High Ca 2+ Close to IP 3 -Sensitive Channels that Are Sensed by Neighboring Mitochondria

  Science · 1993 · 10.1126/science.8235595

• Rapid changes of mitochondrial Ca2+ revealed by specifically targeted recombinant aequorin

  Nature · 1992 · 10.1038/358325a0

• A Direct Repeat Is a Hotspot for Large-Scale Deletion of Human Mitochondrial DNA

  Science · 1989 · 10.1126/science.2711184

Current projects

No projects listed.