Hong Lü

Research interests

Publications

• The mechanism and therapy of aortic aneurysms

  Signal Transduction and Targeted Therapy · 2023 · 10.1038/s41392-023-01325-7

• Untargeted metabolomics identifies succinate as a biomarker and therapeutic target in aortic aneurysm and dissection

  European Heart Journal · 2021 · 10.1093/eurheartj/ehab605

• Inhibition of macrophage histone demethylase JMJD3 protects against abdominal aortic aneurysms

  The Journal of Experimental Medicine · 2021 · 10.1084/jem.20201839

• Aortic Aneurysms and Dissections Series

  Arteriosclerosis Thrombosis and Vascular Biology · 2020 · 10.1161/atvbaha.120.313991

• Single-Cell Transcriptome Analysis Reveals Dynamic Cell Populations and Differential Gene Expression Patterns in Control and Aneurysmal Human Aortic Tissue

  Circulation · 2020 · 10.1161/circulationaha.120.046528

• Global Burden of Cardiovascular Diseases and Risk Factors, 1990–2019

  Journal of the American College of Cardiology · 2020 · https://doi.org/10.1016/j.jacc.2020.11.010

• Updates of Recent Aortic Aneurysm Research

  Arteriosclerosis Thrombosis and Vascular Biology · 2019 · 10.1161/atvbaha.119.312000

• Renin-Angiotensin System and Cardiovascular Functions

  Arteriosclerosis Thrombosis and Vascular Biology · 2018 · 10.1161/atvbaha.118.311282

• Consideration of Sex Differences in Design and Reporting of Experimental Arterial Pathology Studies—Statement From ATVB Council

  Arteriosclerosis Thrombosis and Vascular Biology · 2018 · 10.1161/atvbaha.117.309524

• Structure and functions of angiotensinogen

  Hypertension Research · 2016 · 10.1038/hr.2016.17

• Hypercholesterolemia Induced by a PCSK9 Gain-of-Function Mutation Augments Angiotensin II–Induced Abdominal Aortic Aneurysms in C57BL/6 Mice—Brief Report

  Arteriosclerosis Thrombosis and Vascular Biology · 2016 · 10.1161/atvbaha.116.307613

• Atherosclerosis

  Arteriosclerosis Thrombosis and Vascular Biology · 2015 · 10.1161/atvbaha.115.305380

• Subcutaneous Angiotensin II Infusion using Osmotic Pumps Induces Aortic Aneurysms in Mice

  Journal of Visualized Experiments · 2015 · 10.3791/53191

• Angiotensinogen Exerts Effects Independent of Angiotensin II

  Arteriosclerosis Thrombosis and Vascular Biology · 2015 · 10.1161/atvbaha.115.306740

• MicroRNA-155 Deficiency Results in Decreased Macrophage Inflammation and Attenuated Atherogenesis in Apolipoprotein E–Deficient Mice

  Arteriosclerosis Thrombosis and Vascular Biology · 2014 · 10.1161/atvbaha.113.302701

• SIRT4 Represses Peroxisome Proliferator-Activated Receptor α Activity To Suppress Hepatic Fat Oxidation

  Molecular and Cellular Biology · 2013 · 10.1128/mcb.00087-13

• MyD88 Deficiency Attenuates Angiotensin II-Induced Abdominal Aortic Aneurysm Formation Independent of Signaling Through Toll-Like Receptors 2 and 4

  Arteriosclerosis Thrombosis and Vascular Biology · 2011 · 10.1161/atvbaha.111.238642

• Characterization of Sparstolonin B, a Chinese Herb-derived Compound, as a Selective Toll-like Receptor Antagonist with Potent Anti-inflammatory Properties

  Journal of Biological Chemistry · 2011 · 10.1074/jbc.m111.227934

• Molecular and Pathophysiological Features of Angiotensinogen: A Mini Review

  North American Journal of Medicine and Science · 2011 · 10.7156/v4i4p183

• Complex pathologies of angiotensin II-induced abdominal aortic aneurysms

  Journal of Zhejiang University SCIENCE B · 2011 · 10.1631/jzus.b1101002

• Renin inhibition reduces hypercholesterolemia-induced atherosclerosis in mice

  Journal of Clinical Investigation · 2008 · 10.1172/jci32970

• Angiotensin II increases adipose angiotensinogen expression

  American Journal of Physiology-Endocrinology and Metabolism · 2007 · 10.1152/ajpendo.00277.2006

• Bone Marrow Transplantation Reveals That Recipient AT1a Receptors Are Required to Initiate Angiotensin II–Induced Atherosclerosis and Aneurysms

  Arteriosclerosis Thrombosis and Vascular Biology · 2006 · 10.1161/01.atv.0000254680.71485.92

• Hypercholesterolemia Stimulates Angiotensin Peptide Synthesis and Contributes to Atherosclerosis Through the AT 1A Receptor

  Circulation · 2004 · 10.1161/01.cir.0000150540.54220.c4

• Association of Estrogen Receptor-α Gene Polymorphisms With Coronary Artery Disease in Patients With Familial Hypercholesterolemia

  Arteriosclerosis Thrombosis and Vascular Biology · 2002 · 10.1161/01.atv.0000014424.18209.21

Current projects

No projects listed.