Masashi Yanagisawa

Research interests

Publications

• Olfactory receptor responding to gut microbiota-derived signals plays a role in renin secretion and blood pressure regulation

  Proceedings of the National Academy of Sciences · 2013 · https://doi.org/10.1073/pnas.1215927110

• Short-Chain Fatty Acids Activate GPR41 and GPR43 on Intestinal Epithelial Cells to Promote Inflammatory Responses in Mice

  Gastroenterology · 2013 · 10.1053/j.gastro.2013.04.056

• The orexigenic hormone ghrelin defends against depressive symptoms of chronic stress

  Nature Neuroscience · 2008 · 10.1038/nn.2139

• Effects of the gut microbiota on host adiposity are modulated by the short-chain fatty-acid binding G protein-coupled receptor, Gpr41

  Proceedings of the National Academy of Sciences · 2008 · https://doi.org/10.1073/pnas.0808567105

• Short-chain fatty acids stimulate leptin production in adipocytes through the G protein-coupled receptor GPR41

  Proceedings of the National Academy of Sciences · 2004 · 10.1073/pnas.2637002100

• Hypothalamic Orexin Neurons Regulate Arousal According to Energy Balance in Mice

  Neuron · 2003 · 10.1016/s0896-6273(03)00331-3

• Activation of peroxisome proliferator-activated receptor δ induces fatty acid β-oxidation in skeletal muscle and attenuates metabolic syndrome

  Proceedings of the National Academy of Sciences · 2003 · 10.1073/pnas.0306981100

• Distinct Narcolepsy Syndromes in Orexin Receptor-2 and Orexin Null Mice

  Neuron · 2003 · 10.1016/s0896-6273(03)00330-1

• Tie2-Cre Transgenic Mice: A New Model for Endothelial Cell-Lineage Analysis in Vivo

  Developmental Biology · 2001 · https://doi.org/10.1006/dbio.2000.0106

• Fos Expression in Orexin Neurons Varies with Behavioral State

  Journal of Neuroscience · 2001 · https://doi.org/10.1523/jneurosci.21-05-01656.2001

• Differential expression of orexin receptors 1 and 2 in the rat brain

  The Journal of Comparative Neurology · 2001 · https://doi.org/10.1002/cne.1190

• Genetic Ablation of Orexin Neurons in Mice Results in Narcolepsy, Hypophagia, and Obesity

  Neuron · 2001 · 10.1016/s0896-6273(01)00293-8

• To Eat or to Sleep? Orexin in the Regulation of Feeding and Wakefulness

  Annual Review of Neuroscience · 2001 · 10.1146/annurev.neuro.24.1.429

• Endothelin System: The Double-Edged Sword in Health and Disease

  The Annual Review of Pharmacology and Toxicology · 2001 · 10.1146/annurev.pharmtox.41.1.851

• Orexins, orexigenic hypothalamic peptides, interact with autonomic, neuroendocrine and neuroregulatory systems

  Proceedings of the National Academy of Sciences · 1999 · 10.1073/pnas.96.2.748

• Narcolepsy in orexin Knockout Mice

  Cell · 1999 · https://doi.org/10.1016/s0092-8674(00)81973-x

• Distribution of orexin neurons in the adult rat brain

  Brain Research · 1999 · 10.1016/s0006-8993(99)01336-0

• Cranial and cardiac neural crest defects in endothelin-A receptor-deficient mice

  Development · 1998 · 10.1242/dev.125.5.813

• Targeted and natural (piebald-lethal) mutations of endothelin-B receptor gene produce megacolon associated with spotted coat color in mice

  Cell · 1994 · 10.1016/0092-8674(94)90017-5

• A missense mutation of the endothelin-B receptor gene in multigenic hirschsprung's disease

  Cell · 1994 · 10.1016/0092-8674(94)90016-7

• Interaction of endothelin-3 with endothelin-B receptor is essential for development of epidermal melanocytes and enteric neurons

  Cell · 1994 · 10.1016/0092-8674(94)90018-3

• Expression of Endothelin-1 in the Lungs of Patients with Pulmonary Hypertension

  New England Journal of Medicine · 1993 · https://doi.org/10.1056/nejm199306173282402

• Cloning of a cDNA encoding a non-isopeptide-selective subtype of the endothelin receptor

  Nature · 1990 · https://doi.org/10.1038/348732a0

• The human endothelin family: three structurally and pharmacologically distinct isopeptides predicted by three separate genes.

  Proceedings of the National Academy of Sciences · 1989 · https://doi.org/10.1073/pnas.86.8.2863

• A novel potent vasoconstrictor peptide produced by vascular endothelial cells

  Nature · 1988 · https://doi.org/10.1038/332411a0

Current projects

No projects listed.