Rosa Rademakers

Research interests

Publications

• Temporal order of clinical and biomarker changes in familial frontotemporal dementia

  Nature Medicine · 2022 · https://doi.org/10.1038/s41591-022-01942-9

• Plasma Neurofilament Light for Prediction of Disease Progression in Familial Frontotemporal Lobar Degeneration

  Neurology · 2021 · https://doi.org/10.1212/wnl.0000000000011848

• Limbic-predominant age-related TDP-43 encephalopathy (LATE): consensus working group report

  Brain · 2019 · https://doi.org/10.1093/brain/awz099

• Age at symptom onset and death and disease duration in genetic frontotemporal dementia: an international retrospective cohort study

  The Lancet Neurology · 2019 · https://doi.org/10.1016/s1474-4422(19)30394-1

• Progranulin Deficiency Promotes Circuit-Specific Synaptic Pruning by Microglia via Complement Activation

  Cell · 2016 · https://doi.org/10.1016/j.cell.2016.04.001

• Network degeneration and dysfunction in presymptomatic C9ORF72 expansion carriers

  NeuroImage Clinical · 2016 · https://doi.org/10.1016/j.nicl.2016.12.006

• Genome-wide association study of corticobasal degeneration identifies risk variants shared with progressive supranuclear palsy

  Nature Communications · 2015 · https://doi.org/10.1038/ncomms8247

• Mutations in prion-like domains in hnRNPA2B1 and hnRNPA1 cause multisystem proteinopathy and ALS

  Nature · 2013 · https://doi.org/10.1038/nature11922

• Unconventional Translation of C9ORF72 GGGGCC Expansion Generates Insoluble Polypeptides Specific to c9FTD/ALS

  Neuron · 2013 · https://doi.org/10.1016/j.neuron.2013.02.004

• TREM2 Variants in Alzheimer's Disease

  New England Journal of Medicine · 2012 · https://doi.org/10.1056/nejmoa1211851

• FET proteins TAF15 and EWS are selective markers that distinguish FTLD with FUS pathology from amyotrophic lateral sclerosis with FUS mutations

  Brain · 2011 · https://doi.org/10.1093/brain/awr201

• Expanded GGGGCC Hexanucleotide Repeat in Noncoding Region of C9ORF72 Causes Chromosome 9p-Linked FTD and ALS

  Neuron · 2011 · https://doi.org/10.1016/j.neuron.2011.09.011

• Identification of common variants influencing risk of the tauopathy progressive supranuclear palsy

  Nature Genetics · 2011 · 10.1038/ng.859

• FUS pathology defines the majority of tau- and TDP-43-negative frontotemporal lobar degeneration

  Acta Neuropathologica · 2010 · https://doi.org/10.1007/s00401-010-0698-6

• Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions

  Nature Genetics · 2010 · 10.1038/ng.536

• Progranulin mutations and amyotrophic lateral sclerosis or amyotrophic lateral sclerosis-frontotemporal dementia phenotypes

  Journal of Neurology Neurosurgery & Psychiatry · 2006 · https://doi.org/10.1136/jnnp.2006.109553

• Mutations in progranulin cause tau-negative frontotemporal dementia linked to chromosome 17

  Nature · 2006 · https://doi.org/10.1038/nature05016

• High-density SNP haplotyping suggests altered regulation of tau gene expression in progressive supranuclear palsy

  Human Molecular Genetics · 2005 · https://doi.org/10.1093/hmg/ddi361

Current projects

No projects listed.