Tom Vanden Berghe

Research interests

Publications

• Cancer cells dying from ferroptosis impede dendritic cell-mediated anti-tumor immunity

  Nature Communications · 2022 · https://doi.org/10.1038/s41467-022-31218-2

• The molecular machinery of regulated cell death

  Cell Research · 2019 · https://doi.org/10.1038/s41422-019-0164-5

• Targeting Ferroptosis to Iron Out Cancer

  Cancer Cell · 2019 · https://doi.org/10.1016/j.ccell.2019.04.002

• To NET or not to NET:current opinions and state of the science regarding the formation of neutrophil extracellular traps

  Cell Death and Differentiation · 2019 · https://doi.org/10.1038/s41418-018-0261-x

• Nano-targeted induction of dual ferroptotic mechanisms eradicates high-risk neuroblastoma

  Journal of Clinical Investigation · 2018 · https://doi.org/10.1172/jci99032

• Initiation and execution mechanisms of necroptosis: an overview

  Cell Death and Differentiation · 2017 · https://doi.org/10.1038/cdd.2017.65

• Essential versus accessory aspects of cell death: recommendations of the NCCD 2015

  Cell Death and Differentiation · 2014 · https://doi.org/10.1038/cdd.2014.137

• Regulated necrosis: the expanding network of non-apoptotic cell death pathways

  Nature Reviews Molecular Cell Biology · 2014 · https://doi.org/10.1038/nrm3737

• Synchronized renal tubular cell death involves ferroptosis

  Proceedings of the National Academy of Sciences · 2014 · https://doi.org/10.1073/pnas.1415518111

• RIP Kinase-Dependent Necrosis Drives Lethal Systemic Inflammatory Response Syndrome

  Immunity · 2011 · https://doi.org/10.1016/j.immuni.2011.09.020

• Dying for a cause: NETosis, mechanisms behind an antimicrobial cell death modality

  Cell Death and Differentiation · 2011 · https://doi.org/10.1038/cdd.2011.1

• Autophagy: for better or for worse

  Cell Research · 2011 · https://doi.org/10.1038/cr.2011.152

• The Role of the Kinases RIP1 and RIP3 in TNF-Induced Necrosis

  Science Signaling · 2010 · https://doi.org/10.1126/scisignal.3115re4

• Caspase-mediated cleavage of Beclin-1 inactivates Beclin-1-induced autophagy and enhances apoptosis by promoting the release of proapoptotic factors from mitochondria

  Cell Death and Disease · 2010 · https://doi.org/10.1038/cddis.2009.16

• Molecular mechanisms of necroptosis: an ordered cellular explosion

  Nature Reviews Molecular Cell Biology · 2010 · https://doi.org/10.1038/nrm2970

• Neutrophil extracellular trap cell death requires both autophagy and superoxide generation

  Cell Research · 2010 · 10.1038/cr.2010.150

• RIP Kinases at the Crossroads of Cell Death and Survival

  Cell · 2009 · https://doi.org/10.1016/j.cell.2009.07.006

• Necroptosis, necrosis and secondary necrosis converge on similar cellular disintegration features

  Cell Death and Differentiation · 2009 · https://doi.org/10.1038/cdd.2009.184

• Apoptosis and necrosis: Detection, discrimination and phagocytosis

  Methods · 2008 · https://doi.org/10.1016/j.ymeth.2007.12.001

• RIP1, a kinase on the crossroads of a cell's decision to live or die

  Cell Death and Differentiation · 2007 · https://doi.org/10.1038/sj.cdd.4402085

• Caspases in cell survival, proliferation and differentiation

  Cell Death and Differentiation · 2006 · https://doi.org/10.1038/sj.cdd.4402047

• Necrosis, a well-orchestrated form of cell demise: Signalling cascades, important mediators and concomitant immune response

  Biochimica et Biophysica Acta (BBA) - Bioenergetics · 2006 · https://doi.org/10.1016/j.bbabio.2006.06.014

Current projects

No projects listed.