Katriina Aalto‐Setälä

Research interests

Publications

• Author Correction: FinnGen provides genetic insights from a well-phenotyped isolated population

  Nature · 2023 · https://doi.org/10.1038/s41586-023-05837-8

• FinnGen provides genetic insights from a well-phenotyped isolated population

  Nature · 2023 · https://doi.org/10.1038/s41586-022-05473-8

• FinnGen: Unique genetic insights from combining isolated population and national health register data

  medRxiv · 2022 · 10.1101/2022.03.03.22271360

• Mechanically Biomimetic Gelatin–Gellan Gum Hydrogels for 3D Culture of Beating Human Cardiomyocytes

  ACS Applied Materials & Interfaces · 2019 · 10.1021/acsami.8b22343

• Antiarrhythmic Effects of Dantrolene in Patients with Catecholaminergic Polymorphic Ventricular Tachycardia and Replication of the Responses Using iPSC Models

  PLoS ONE · 2015 · 10.1371/journal.pone.0125366

• Mutation‐Specific Phenotypes in hiPSC‐Derived Cardiomyocytes Carrying Either Myosin‐Binding Protein C Or α ‐Tropomyosin Mutation for Hypertrophic Cardiomyopathy

  Stem Cells International · 2015 · 10.1155/2016/1684792

• Video image-based analysis of single human induced pluripotent stem cell derived cardiomyocyte beating dynamics using digital image correlation

  BioMedical Engineering OnLine · 2014 · 10.1186/1475-925x-13-39

• Calcium Transients Closely Reflect Prolonged Action Potentials in iPSC Models of Inherited Cardiac Arrhythmia

  Stem Cell Reports · 2014 · 10.1016/j.stemcr.2014.06.003

• Computational Models of Ventricular- and Atrial-Like Human Induced Pluripotent Stem Cell Derived Cardiomyocytes

  Annals of Biomedical Engineering · 2013 · https://doi.org/10.1007/s10439-013-0833-3

• Cell Model of Catecholaminergic Polymorphic Ventricular Tachycardia Reveals Early and Delayed Afterdepolarizations

  PLoS ONE · 2012 · https://doi.org/10.1371/journal.pone.0044660

• Model for long QT syndrome type 2 using human iPS cells demonstrates arrhythmogenic characteristics in cell culture

  Disease Models & Mechanisms · 2011 · 10.1242/dmm.008409

• Cardiac Differentiation of Pluripotent Stem Cells

  Stem Cells International · 2011 · https://doi.org/10.4061/2011/383709

• A Defined and Xeno-Free Culture Method Enabling the Establishment of Clinical-Grade Human Embryonic, Induced Pluripotent and Adipose Stem Cells

  PLoS ONE · 2010 · https://doi.org/10.1371/journal.pone.0010246

• Obtaining Consent for Future Research with Induced Pluripotent Cells: Opportunities and Challenges

  PLoS Biology · 2009 · 10.1371/journal.pbio.1000042

• DNA hypomethylation and methyltransferase expression in atherosclerotic lesions

  Vascular Medicine · 2002 · https://doi.org/10.1191/1358863x02vm418oa

• Decreased HDL cholesterol levels but normal lipid absorption, growth, and feeding behavior in apolipoprotein A-IV knockout mice

  Journal of Lipid Research · 1997 · 10.1016/s0022-2275(20)37153-4

• Further characterization of the metabolic properties of triglyceride-rich lipoproteins from human and mouse apoC-III transgenic mice.

  Journal of Lipid Research · 1996 · 10.1016/s0022-2275(20)39123-9

• Severe hypertriglyceridemia, reduced high density lipoprotein, and neonatal death in lipoprotein lipase knockout mice. Mild hypertriglyceridemia with impaired very low density lipoprotein clearance in heterozygotes.

  Journal of Clinical Investigation · 1995 · 10.1172/jci118319

• Severe hypercholesterolemia and atherosclerosis in apolipoprotein E-deficient mice created by homologous recombination in ES cells

  Cell · 1992 · https://doi.org/10.1016/0092-8674(92)90362-g

• The familial hypercholesterolemia (FH)-North Karelia mutation of the low density lipoprotein receptor gene deletes seven nucleotides of exon 6 and is a common cause of FH in Finland.

  Journal of Clinical Investigation · 1992 · 10.1172/jci115839

• Lipoproteins and their genetic variation in subjects with and without angiographically verified coronary artery disease.

  Arteriosclerosis and Thrombosis A Journal of Vascular Biology · 1992 · 10.1161/01.atv.12.1.58

• Mechanism of hypertriglyceridemia in human apolipoprotein (apo) CIII transgenic mice. Diminished very low density lipoprotein fractional catabolic rate associated with increased apo CIII and reduced apo E on the particles.

  Journal of Clinical Investigation · 1992 · 10.1172/jci116066

• A primer-guided nucleotide incorporation assay in the genotyping of apolipoprotein E

  Genomics · 1990 · 10.1016/0888-7543(90)90255-s

• Finnish type of low density lipoprotein receptor gene mutation (FH-Helsinki) deletes exons encoding the carboxy-terminal part of the receptor and creates an internalization-defective phenotype.

  Journal of Clinical Investigation · 1989 · 10.1172/jci114192

• Primary structure of human insulin‐like growth factor‐binding protein/placental protein 12 and tissue‐specific expression of its mRNA

  FEBS Letters · 1988 · https://doi.org/10.1016/0014-5793(88)80041-3

Current projects

No projects listed.