Giovanni Tonon

Research interests

Publications

• Immune signature drives leukemia escape and relapse after hematopoietic cell transplantation

  Nature Medicine · 2019 · https://doi.org/10.1038/s41591-019-0400-z

• Microbiota-driven interleukin-17-producing cells and eosinophils synergize to accelerate multiple myeloma progression

  Nature Communications · 2018 · https://doi.org/10.1038/s41467-018-07305-8

• Rescue of Hippo coactivator YAP1 triggers DNA damage–induced apoptosis in hematological cancers

  Nature Medicine · 2014 · https://doi.org/10.1038/nm.3562

• Contrasting roles of histone 3 lysine 27 demethylases in acute lymphoblastic leukaemia

  Nature · 2014 · https://doi.org/10.1038/nature13605

• Pancreatic cancers require autophagy for tumor growth

  Genes & Development · 2011 · https://doi.org/10.1101/gad.2016111

• Telomere dysfunction induces metabolic and mitochondrial compromise

  Nature · 2011 · https://doi.org/10.1038/nature09787

• Somatic mutations of the histone H3K27 demethylase gene UTX in human cancer

  Nature Genetics · 2009 · https://doi.org/10.1038/ng.349

• p53 and Pten control neural and glioma stem/progenitor cell renewal and differentiation

  Nature · 2008 · https://doi.org/10.1038/nature07443

• Somatic mutations affect key pathways in lung adenocarcinoma

  Nature · 2008 · https://doi.org/10.1038/nature07423

• The Differentiation and Stress Response Factor XBP-1 Drives Multiple Myeloma Pathogenesis

  Cancer Cell · 2007 · https://doi.org/10.1016/j.ccr.2007.02.015

• Understanding multiple myeloma pathogenesis in the bone marrow to identify new therapeutic targets

  Nature reviews. Cancer · 2007 · https://doi.org/10.1038/nrc2189

• High-resolution genomic profiles define distinct clinico-pathogenetic subgroups of multiple myeloma patients

  Cancer Cell · 2006 · https://doi.org/10.1016/j.ccr.2006.03.019

• The small-molecule VEGF receptor inhibitor pazopanib (GW786034B) targets both tumor and endothelial cells in multiple myeloma

  Proceedings of the National Academy of Sciences · 2006 · https://doi.org/10.1073/pnas.0609329103

• Integrating data on DNA copy number with gene expression levels and drug sensitivities in the NCI-60 cell line panel

  Molecular Cancer Therapeutics · 2006 · https://doi.org/10.1158/1535-7163.mct-05-0155

• K-ras activation generates an inflammatory response in lung tumors

  Oncogene · 2005 · https://doi.org/10.1038/sj.onc.1209237

• High-resolution genomic profiles of human lung cancer

  Proceedings of the National Academy of Sciences · 2005 · https://doi.org/10.1073/pnas.0504126102

• t(11;19)(q21;p13) translocation in mucoepidermoid carcinoma creates a novel fusion product that disrupts a Notch signaling pathway

  Nature Genetics · 2003 · https://doi.org/10.1038/ng1083

• Karyotypic complexity of the NCI-60 drug-screening panel.

  PubMed · 2003

Current projects

No projects listed.