Paola Panina‐Bordignon

Research interests

Publications

• Neural stem cell transplantation in patients with progressive multiple sclerosis: an open-label, phase 1 study

  Nature Medicine · 2023 · 10.1038/s41591-022-02097-3

• Chromatin Velocity reveals epigenetic dynamics by single-cell profiling of heterochromatin and euchromatin

  Nature Biotechnology · 2021 · 10.1038/s41587-021-01031-1

• The distinguishing cellular and molecular features of the endometriotic ovarian cyst: from pathophysiology to the potential endometrioma-mediated damage to the ovary

  Human Reproduction Update · 2013 · 10.1093/humupd/dmt053

• The surface‐exposed chaperone, Hsp60, is an agonist of the microglial TREM2 receptor

  Journal of Neurochemistry · 2009 · 10.1111/j.1471-4159.2009.06130.x

• Macrophages Are Alternatively Activated in Patients with Endometriosis and Required for Growth and Vascularization of Lesions in a Mouse Model of Disease

  American Journal Of Pathology · 2009 · 10.2353/ajpath.2009.081011

• Identification of soluble TREM-2 in the cerebrospinal fluid and its association with multiple sclerosis and CNS inflammation

  Brain · 2008 · 10.1093/brain/awn217

• Blockade of TREM‐2 exacerbates experimental autoimmune encephalomyelitis

  European Journal of Immunology · 2007 · 10.1002/eji.200636837

• Cycling and early pregnant endometrium as a site of regulated expression of the vitamin D system

  Journal of Molecular Endocrinology · 2006 · 10.1677/jme.1.01946

• Distribution and signaling of TREM2/DAP12, the receptor system mutated in human polycystic lipomembraneous osteodysplasia with sclerosing leukoencephalopathy dementia

  European Journal of Neuroscience · 2004 · 10.1111/j.1460-9568.2004.03729.x

• Production of Profibrotic Cytokines by Invariant NKT Cells Characterizes Cirrhosis Progression in Chronic Viral Hepatitis

  The Journal of Immunology · 2004 · 10.4049/jimmunol.173.2.1417

• Chemokine receptors in inflammation: an overview

  Journal of Immunological Methods · 2003 · 10.1016/s0022-1759(02)00414-3

• Increased Expression of the Chemokine Receptor CXCR3 and Its Ligand CXCL10 in Peripheral Airways of Smokers with Chronic Obstructive Pulmonary Disease

  American Journal of Respiratory and Critical Care Medicine · 2002 · 10.1164/rccm.2107139

• Unique Chemotactic Response Profile and Specific Expression of Chemokine Receptors Ccr4 and Ccr8 by Cd4+Cd25+ Regulatory T Cells

  The Journal of Experimental Medicine · 2001 · https://doi.org/10.1084/jem.194.6.847

• The C-C chemokine receptors CCR4 and CCR8 identify airway T cells of allergen-challenged atopic asthmatics

  Journal of Clinical Investigation · 2001 · 10.1172/jci12655

• Chemokines and Their Receptors Guiding T Lymphocyte Recruitment in Lung Inflammation

  American Journal of Respiratory and Critical Care Medicine · 2001 · 10.1164/ajrccm.164.7.2103011

• Inhibition of Th1 development and treatment of chronic-relapsing experimental allergic encephalomyelitis by a non-hypercalcemic analogue of 1,25-dihydroxyvitamin D3

  European Journal of Immunology · 2000 · 10.1002/1521-4141(200002)30:2<498::aid-immu498>3.0.co;2-q

• Regulation of the IL‐12/IL‐12R axis: a critical step in T‐helper cell differentiation and effector function

  Immunological Reviews · 1999 · 10.1111/j.1600-065x.1999.tb01329.x

• Endometrial ability to implant in ectopic sites can be prevented by interleukin-12 in a murine model of endometriosis

  Human Reproduction · 1999 · 10.1093/humrep/14.12.2944

• Differential Expression of Chemokine Receptors and Chemotactic Responsiveness of Type 1 T Helper Cells (Th1s) and Th2s

  The Journal of Experimental Medicine · 1998 · https://doi.org/10.1084/jem.187.1.129

• Inhibition of IL-12 production by 1,25-dihydroxyvitamin D3. Involvement of NF-kappaB downregulation in transcriptional repression of the p40 gene.

  Journal of Clinical Investigation · 1998 · 10.1172/jci1050

• Beta2-agonists prevent Th1 development by selective inhibition of interleukin 12.

  Journal of Clinical Investigation · 1997 · 10.1172/jci119674

• Cytotoxic T cells specific for glutamic acid decarboxylase in autoimmune diabetes.

  The Journal of Experimental Medicine · 1995 · 10.1084/jem.181.5.1923

• Gene Therapy in Peripheral Blood Lymphocytes and Bone Marrow for ADA − Immunodeficient Patients

  Science · 1995 · https://doi.org/10.1126/science.270.5235.470

• Preferential V beta gene usage and lack of junctional sequence conservation among human T cell receptors specific for a tetanus toxin-derived peptide: evidence for a dominant role of a germline-encoded V region in antigen/major histocompatibility complex recognition.

  The Journal of Experimental Medicine · 1992 · 10.1084/jem.175.3.765

• Universally immunogenic T cell epitopes: promiscuous binding to human MHC class II and promiscuous recognition by T cells

  European Journal of Immunology · 1989 · 10.1002/eji.1830191209

Current projects

No projects listed.