Angelo Quattrini

Research interests

Publications

• Lentiviral haemopoietic stem-cell gene therapy in early-onset metachromatic leukodystrophy: an ad-hoc analysis of a non-randomised, open-label, phase 1/2 trial

  The Lancet · 2016 · 10.1016/s0140-6736(16)30374-9

• Brain conditioning is instrumental for successful microglia reconstitution following hematopoietic stem cell transplantation

  Proceedings of the National Academy of Sciences · 2012 · 10.1073/pnas.1205858109

• TACE (ADAM17) inhibits Schwann cell myelination

  Nature Neuroscience · 2011 · 10.1038/nn.2849

• Mitochondrial biogenesis and fission in axons in cell culture and animal models of diabetic neuropathy

  Acta Neuropathologica · 2010 · 10.1007/s00401-010-0697-7

• Gene therapy augments the efficacy of hematopoietic cell transplantation and fully corrects mucopolysaccharidosis type I phenotype in the mouse model

  Blood · 2010 · 10.1182/blood-2010-04-278234

• Identification of Hematopoietic Stem Cell–Specific miRNAs Enables Gene Therapy of Globoid Cell Leukodystrophy

  Science Translational Medicine · 2010 · 10.1126/scitranslmed.3001522

• Diabetes regulates mitochondrial biogenesis and fission in mouse neurons

  Diabetologia · 2009 · 10.1007/s00125-009-1553-y

• Ablation of the UPR-Mediator CHOP Restores Motor Function and Reduces Demyelination in Charcot-Marie-Tooth 1B Mice

  Neuron · 2008 · 10.1016/j.neuron.2007.12.021

• Alpha-lipoic acid prevents mitochondrial damage and neurotoxicity in experimental chemotherapy neuropathy

  Experimental Neurology · 2008 · 10.1016/j.expneurol.2008.08.013

• β1 integrin activates Rac1 in Schwann cells to generate radial lamellae during axonal sorting and myelination

  The Journal of Cell Biology · 2007 · 10.1083/jcb.200610014

• Different Intracellular Pathomechanisms Produce DiverseMyelin Protein ZeroNeuropathies in Transgenic Mice

  Journal of Neuroscience · 2006 · 10.1523/jneurosci.3819-05.2006

• Gene therapy of metachromatic leukodystrophy reverses neurological damage and deficits in mice

  Journal of Clinical Investigation · 2006 · 10.1172/jci28873

• Loss of glial fibrillary acidic protein (GFAP) impairs Schwann cell proliferation and delays nerve regeneration after damage

  Journal of Cell Science · 2006 · 10.1242/jcs.03168

• Polyneuropathy in POEMS syndrome: role of angiogenic factors in the pathogenesis

  Brain · 2005 · 10.1093/brain/awh519

• Correction of metachromatic leukodystrophy in the mouse model by transplantation of genetically modified hematopoietic stem cells

  Journal of Clinical Investigation · 2004 · 10.1172/jci200419205

• Axonal degeneration in paraplegin-deficient mice is associated with abnormal mitochondria and impairment of axonal transport

  Journal of Clinical Investigation · 2004 · 10.1172/jci20138

• Disruption of Mtmr2 produces CMT4B1-like neuropathy with myelin outfolding and impaired spermatogenesis

  The Journal of Cell Biology · 2004 · 10.1083/jcb.200407010

• Axonal degeneration in paraplegin-deficient mice is associated with abnormal mitochondria and impairment of axonal transport

  Journal of Clinical Investigation · 2004 · 10.1172/jci200420138

• Correction of metachromatic leukodystrophy in the mouse model by transplantation of genetically modified hematopoietic stem cells

  Journal of Clinical Investigation · 2004 · 10.1172/jci19205

• Injection of adult neurospheres induces recovery in a chronic model of multiple sclerosis

  Nature · 2003 · https://doi.org/10.1038/nature01552

• Conditional disruption of β1 integrin in Schwann cells impedes interactions with axons

  The Journal of Cell Biology · 2002 · 10.1083/jcb.200109021

• In vivo gene therapy of metachromatic leukodystrophy by lentiviral vectors: correction of neuropathology and protection against learning impairments in affected mice

  Nature Medicine · 2001 · 10.1038/85454

• Role of integrins in the peripheral nervous system

  Progress in Neurobiology · 2001 · 10.1016/s0301-0082(00)00045-9

• P0 Glycoprotein Overexpression Causes Congenital Hypomyelination of Peripheral Nerves

  The Journal of Cell Biology · 2000 · 10.1083/jcb.148.5.1021

• Evidence of peripheral axonal neuropathy in primary restless legs syndrome

  Movement Disorders · 1995 · 10.1002/mds.870100103

Current projects

No projects listed.