Laurence Zitvogel

Research interests

Publications

• Immunogenic cell stress and death

  Nature Immunology · 2022 · 10.1038/s41590-022-01132-2

• Cross-tissue single-cell landscape of human monocytes and macrophages in health and disease

  Immunity · 2021 · https://doi.org/10.1016/j.immuni.2021.07.007

• The microbiome and human cancer

  Science · 2021 · https://doi.org/10.1126/science.abc4552

• Immunostimulation with chemotherapy in the era of immune checkpoint inhibitors

  Nature Reviews Clinical Oncology · 2020 · 10.1038/s41571-020-0413-z

• Consensus guidelines for the definition, detection and interpretation of immunogenic cell death

  Journal for ImmunoTherapy of Cancer · 2020 · https://doi.org/10.1136/jitc-2019-000337

• Elevated Calprotectin and Abnormal Myeloid Cell Subsets Discriminate Severe from Mild COVID-19

  Cell · 2020 · https://doi.org/10.1016/j.cell.2020.08.002

• Gut microbiome influences efficacy of PD-1–based immunotherapy against epithelial tumors

  Science · 2017 · https://doi.org/10.1126/science.aan3706

• Gut microbiome modulates response to anti–PD-1 immunotherapy in melanoma patients

  Science · 2017 · https://doi.org/10.1126/science.aan4236

• The immune contexture in cancer prognosis and treatment

  Nature Reviews Clinical Oncology · 2017 · 10.1038/nrclinonc.2017.101

• Targeting the tumor microenvironment: removing obstruction to anticancer immune responses and immunotherapy

  Annals of Oncology · 2016 · 10.1093/annonc/mdw168

• Immunogenic Chemotherapy Sensitizes Tumors to Checkpoint Blockade Therapy

  Immunity · 2016 · 10.1016/j.immuni.2015.11.024

• Immunogenic cell death in cancer and infectious disease

  Nature reviews. Immunology · 2016 · 10.1038/nri.2016.107

• Immunological Effects of Conventional Chemotherapy and Targeted Anticancer Agents

  Cancer Cell · 2015 · 10.1016/j.ccell.2015.10.012

• Anticancer immunotherapy by CTLA-4 blockade relies on the gut microbiota

  Science · 2015 · https://doi.org/10.1126/science.aad1329

• Type I interferons in anticancer immunity

  Nature reviews. Immunology · 2015 · 10.1038/nri3845

• Consensus guidelines for the detection of immunogenic cell death

  OncoImmunology · 2014 · 10.4161/21624011.2014.955691

• The Intestinal Microbiota Modulates the Anticancer Immune Effects of Cyclophosphamide

  Science · 2013 · 10.1126/science.1240537

• Immunogenic Cell Death in Cancer Therapy

  Annual Review of Immunology · 2012 · https://doi.org/10.1146/annurev-immunol-032712-100008

• Innate or Adaptive Immunity? The Example of Natural Killer Cells

  Science · 2011 · 10.1126/science.1198687

• Autophagy-Dependent Anticancer Immune Responses Induced by Chemotherapeutic Agents in Mice

  Science · 2011 · 10.1126/science.1208347

• Immunogenic and tolerogenic cell death

  Nature reviews. Immunology · 2009 · 10.1038/nri2545

• Activation of the NLRP3 inflammasome in dendritic cells induces IL-1β–dependent adaptive immunity against tumors

  Nature Medicine · 2009 · 10.1038/nm.2028

• Toll-like receptor 4–dependent contribution of the immune system to anticancer chemotherapy and radiotherapy

  Nature Medicine · 2007 · 10.1038/nm1622

• Immunological aspects of cancer chemotherapy

  Nature reviews. Immunology · 2007 · 10.1038/nri2216

• Cancer despite immunosurveillance: immunoselection and immunosubversion

  Nature reviews. Immunology · 2006 · 10.1038/nri1936

• Calreticulin exposure dictates the immunogenicity of cancer cell death

  Nature Medicine · 2006 · 10.1038/nm1523

• CD4+CD25+ regulatory T cells inhibit natural killer cell functions in a transforming growth factor–β–dependent manner

  The Journal of Experimental Medicine · 2005 · 10.1084/jem.20051511

• Caspase-dependent immunogenicity of doxorubicin-induced tumor cell death

  The Journal of Experimental Medicine · 2005 · 10.1084/jem.20050915

• Vaccination of metastatic melanoma patients with autologous dendritic cell (DC) derived-exosomes: results of thefirst phase I clinical trial

  Journal of Translational Medicine · 2005 · 10.1186/1479-5876-3-10

• Antigen Presentation and T Cell Stimulation by Dendritic Cells

  Annual Review of Immunology · 2002 · 10.1146/annurev.immunol.20.100301.064828

• Exosomes: composition, biogenesis and function

  Nature reviews. Immunology · 2002 · https://doi.org/10.1038/nri855

• Malignant effusions and immunogenic tumour-derived exosomes

  The Lancet · 2002 · 10.1016/s0140-6736(02)09552-1

• Tumor-derived exosomes are a source of shared tumor rejection antigens for CTL cross-priming

  Nature Medicine · 2001 · 10.1038/85438

• Molecular Characterization of Dendritic Cell-Derived Exosomes

  The Journal of Cell Biology · 1999 · 10.1083/jcb.147.3.599

• Eradication of established murine tumors using a novel cell-free vaccine: dendritic cell derived exosomes

  Nature Medicine · 1998 · 10.1038/nm0598-594

Current projects

No projects listed.