Jorma Toppari

Research interests

Publications

• A combined risk score enhances prediction of type 1 diabetes among susceptible children

  Nature Medicine · 2020 · https://doi.org/10.1038/s41591-020-0930-4

• European Academy of Andrology (EAA) guidelines on investigation, treatment and monitoring of functional hypogonadism in males

  Andrology · 2020 · https://doi.org/10.1111/andr.12770

• Prospective virome analyses in young children at increased genetic risk for type 1 diabetes

  Nature Medicine · 2019 · https://doi.org/10.1038/s41591-019-0667-0

• Predicting Islet Cell Autoimmunity and Type 1 Diabetes: An 8-Year TEDDY Study Progress Report

  Diabetes Care · 2019 · https://doi.org/10.2337/dc18-2282

• Predicting Islet Cell Autoimmunity and Type 1 Diabetes: An 8-Year TEDDY Study Progress Report

  Diabetes Care · 2019 · https://doi.org/10.2337/dc18-2282

• Low-Dose Anti-Thymocyte Globulin Preserves C-Peptide, Reduces HbA1c, and Increases Regulatory to Conventional T-Cell Ratios in New-Onset Type 1 Diabetes: Two-Year Clinical Trial Data

  Diabetes · 2019 · https://doi.org/10.2337/db19-0057

• The human gut microbiome in early-onset type 1 diabetes from the TEDDY study

  Nature · 2018 · https://doi.org/10.1038/s41586-018-0620-2

• Temporal development of the gut microbiome in early childhood from the TEDDY study

  Nature · 2018 · https://doi.org/10.1038/s41586-018-0617-x

• Genetic scores to stratify risk of developing multiple islet autoantibodies and type 1 diabetes: A prospective study in children

  PLoS Medicine · 2018 · https://doi.org/10.1371/journal.pmed.1002548

• The Environmental Determinants of Diabetes in the Young (TEDDY) Study: 2018 Update

  Current Diabetes Reports · 2018 · https://doi.org/10.1007/s11892-018-1113-2

• Genetic and Environmental Interactions Modify the Risk of Diabetes-Related Autoimmunity by 6 Years of Age: The TEDDY Study

  Diabetes Care · 2017 · https://doi.org/10.2337/dc17-0238

• The Influence of Type 1 Diabetes Genetic Susceptibility Regions, Age, Sex, and Family History on the Progression From Multiple Autoantibodies to Type 1 Diabetes: A TEDDY Study Report

  Diabetes · 2017 · https://doi.org/10.2337/db17-0261

• Respiratory infections are temporally associated with initiation of type 1 diabetes autoimmunity: the TEDDY study

  Diabetologia · 2017 · https://doi.org/10.1007/s00125-017-4365-5

• Varicocele Is Associated with Impaired Semen Quality and Reproductive Hormone Levels: A Study of 7035 Healthy Young Men from Six European Countries

  European Urology · 2016 · https://doi.org/10.1016/j.eururo.2016.06.044

• Factors That Increase Risk of Celiac Disease Autoimmunity After a Gastrointestinal Infection in Early Life

  Clinical Gastroenterology and Hepatology · 2016 · https://doi.org/10.1016/j.cgh.2016.10.033

• EDC-2: The Endocrine Society's Second Scientific Statement on Endocrine-Disrupting Chemicals

  Endocrine Reviews · 2015 · https://doi.org/10.1210/er.2015-1010

• The 6 year incidence of diabetes-associated autoantibodies in genetically at-risk children: the TEDDY study

  Diabetologia · 2015 · https://doi.org/10.1007/s00125-015-3514-y

• Male Reproductive Disorders and Fertility Trends: Influences of Environment and Genetic Susceptibility

  Physiological Reviews · 2015 · https://doi.org/10.1152/physrev.00017.2015

• Role of Type 1 Diabetes–Associated SNPs on Risk of Autoantibody Positivity in the TEDDY Study

  Diabetes · 2014 · https://doi.org/10.2337/db14-1497

• Human semen quality in the new millennium: a prospective cross-sectional population-based study of 4867 men

  BMJ Open · 2012 · https://doi.org/10.1136/bmjopen-2012-000990

• Intrauterine exposure to mild analgesics is a risk factor for development of male reproductive disorders in human and rat

  Human Reproduction · 2010 · https://doi.org/10.1093/humrep/deq323

• Persistent Pesticides in Human Breast Milk and Cryptorchidism

  Environmental Health Perspectives · 2006 · https://doi.org/10.1289/ehp.8741

• Human Breast Milk Contamination with Phthalates and Alterations of Endogenous Reproductive Hormones in Infants Three Months of Age

  Environmental Health Perspectives · 2005 · https://doi.org/10.1289/ehp.8075

• The Timing of Normal Puberty and the Age Limits of Sexual Precocity: Variations around the World, Secular Trends, and Changes after Migration

  Endocrine Reviews · 2003 · https://doi.org/10.1210/er.2002-0019

• Regional differences in semen quality in Europe

  Human Reproduction · 2001 · https://doi.org/10.1093/humrep/16.5.1012

• Longitudinal Reproductive Hormone Profiles in Infants: Peak of Inhibin B Levels in Infant Boys Exceeds Levels in Adult Men1

  The Journal of Clinical Endocrinology & Metabolism · 1998 · https://doi.org/10.1210/jcem.83.2.4603

• Male reproductive health and environmental xenoestrogens.

  Environmental Health Perspectives · 1996 · https://doi.org/10.1289/ehp.96104s4741

• Male Reproductive Health and Environmental Xenoestrogens

  Environmental Health Perspectives · 1996 · https://doi.org/10.2307/3432709

Current projects

No projects listed.