Eeva‐Liisa Eskelinen

Research interests

Publications

• Autophagy in major human diseases

  The EMBO Journal · 2021 · https://doi.org/10.15252/embj.2021108863

• p62/SQSTM1-droplet serves as a platform for autophagosome formation and anti-oxidative stress response

  Nature Communications · 2021 · https://doi.org/10.1038/s41467-020-20185-1

• Promoting the clearance of neurotoxic proteins in neurodegenerative disorders of ageing

  Nature Reviews Drug Discovery · 2018 · https://doi.org/10.1038/nrd.2018.109

• Molecular definitions of autophagy and related processes

  The EMBO Journal · 2017 · https://doi.org/10.15252/embj.201796697

• 3D tomography reveals connections between the phagophore and endoplasmic reticulum

  Autophagy · 2009 · https://doi.org/10.4161/auto.5.8.10274

• Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes

  Autophagy · 2008 · https://doi.org/10.4161/auto.5338

• Autophagy: A lysosomal degradation pathway with a central role in health and disease

  Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · 2008 · https://doi.org/10.1016/j.bbamcr.2008.07.014

• LAMP proteins are required for fusion of lysosomes with phagosomes

  The EMBO Journal · 2007 · https://doi.org/10.1038/sj.emboj.7601511

• Roles of LAMP-1 and LAMP-2 in lysosome biogenesis and autophagy

  Molecular Aspects of Medicine · 2006 · https://doi.org/10.1016/j.mam.2006.08.005

• Maturation of Autophagic Vacuoles in Mammalian Cells

  Autophagy · 2005 · https://doi.org/10.4161/auto.1.1.1270

• The apoptosis/autophagy paradox: autophagic vacuolization before apoptotic death

  Journal of Cell Science · 2005 · https://doi.org/10.1242/jcs.02447

• Role for Rab7 in maturation of late autophagic vacuoles

  Journal of Cell Science · 2004 · https://doi.org/10.1242/jcs.01370

• At the acidic edge: emerging functions for lysosomal membrane proteins

  Trends in Cell Biology · 2003 · https://doi.org/10.1016/s0962-8924(03)00005-9

• Autophagy Genes Are Essential for Dauer Development and Life-Span Extension in C. elegans

  Science · 2003 · https://doi.org/10.1126/science.1087782

• Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene

  Journal of Clinical Investigation · 2003 · https://doi.org/10.1172/jci20039

• Role of LAMP-2 in Lysosome Biogenesis and Autophagy

  Molecular Biology of the Cell · 2002 · https://doi.org/10.1091/mbc.e02-02-0114

• Regulation of starvation- and virus-induced autophagy by the eIF2α kinase signaling pathway

  Proceedings of the National Academy of Sciences · 2001 · https://doi.org/10.1073/pnas.012485299

• Accumulation of autophagic vacuoles and cardiomyopathy in LAMP-2-deficient mice

  Nature · 2000 · https://doi.org/10.1038/35022595

• μ1A‐adaptin‐deficient mice: lethality, loss of AP‐1 binding and rerouting of mannose 6‐phosphate receptors

  The EMBO Journal · 2000 · https://doi.org/10.1093/emboj/19.10.2193

Current projects

No projects listed.