Pierce K. H. Chow

Research interests

Publications

• The Lancet Commission on addressing the global hepatocellular carcinoma burden: comprehensive strategies from prevention to treatment

  The Lancet · 2025 · https://doi.org/10.1016/s0140-6736(25)01042-6

• Atezolizumab plus bevacizumab versus active surveillance in patients with resected or ablated high-risk hepatocellular carcinoma (IMbrave050): a randomised, open-label, multicentre, phase 3 trial

  The Lancet · 2023 · https://doi.org/10.1016/s0140-6736(23)01796-8

• Cross-tissue single-cell landscape of human monocytes and macrophages in health and disease

  Immunity · 2021 · https://doi.org/10.1016/j.immuni.2021.07.007

• Onco-fetal Reprogramming of Endothelial Cells Drives Immunosuppressive Macrophages in Hepatocellular Carcinoma

  Cell · 2020 · https://doi.org/10.1016/j.cell.2020.08.040

• IMbrave 050: A Phase III Trial of Atezolizumab Plus Bevacizumab in High-Risk Hepatocellular Carcinoma after Curative Resection or Ablation

  Future Oncology · 2020 · https://doi.org/10.2217/fon-2020-0162

• Multidimensional analyses reveal distinct immune microenvironment in hepatitis B virus-related hepatocellular carcinoma

  Gut · 2018 · https://doi.org/10.1136/gutjnl-2018-316510

• SIRveNIB: Selective Internal Radiation Therapy Versus Sorafenib in Asia-Pacific Patients With Hepatocellular Carcinoma

  Journal of Clinical Oncology · 2018 · https://doi.org/10.1200/jco.2017.76.0892

• Immune activation underlies a sustained clinical response to Yttrium-90 radioembolisation in hepatocellular carcinoma

  Gut · 2018 · https://doi.org/10.1136/gutjnl-2017-315485

• Delineation of an immunosuppressive gradient in hepatocellular carcinoma using high-dimensional proteomic and transcriptomic analyses

  Proceedings of the National Academy of Sciences · 2017 · https://doi.org/10.1073/pnas.1706559114

• Whole-Genome and Epigenomic Landscapes of Etiologically Distinct Subtypes of Cholangiocarcinoma

  Cancer Discovery · 2017 · https://doi.org/10.1158/2159-8290.cd-17-0368

• Tumor‐adjacent tissue co‐expression profile analysis reveals pro‐oncogenic ribosomal gene signature for prognosis of resectable hepatocellular carcinoma

  Molecular Oncology · 2017 · https://doi.org/10.1002/1878-0261.12153

• Interaction between tumour-infiltrating B cells and T cells controls the progression of hepatocellular carcinoma

  Gut · 2015 · https://doi.org/10.1136/gutjnl-2015-310814

• Transferrin-conjugated magnetic silica PLGA nanoparticles loaded with doxorubicin and paclitaxel for brain glioma treatment

  Biomaterials · 2013 · https://doi.org/10.1016/j.biomaterials.2013.07.075

• Exome sequencing identifies distinct mutational patterns in liver fluke–related and non-infection-related bile duct cancers

  Nature Genetics · 2013 · https://doi.org/10.1038/ng.2806

• Systematic review of outcomes of liver resection for early hepatocellular carcinoma within the Milan criteria

  British journal of surgery · 2012 · https://doi.org/10.1002/bjs.8915

• Microvascular Invasion Is a Better Predictor of Tumor Recurrence and Overall Survival Following Surgical Resection for Hepatocellular Carcinoma Compared to the Milan Criteria

  Annals of Surgery · 2011 · https://doi.org/10.1097/sla.0b013e31821ad884

• Lethal-7 is down-regulated by the hepatitis B virus x protein and targets signal transducer and activator of transcription 3

  Journal of Hepatology · 2010 · https://doi.org/10.1016/j.jhep.2009.12.043

• Asian Pacific Association for the Study of the Liver consensus recommendations on hepatocellular carcinoma

  Hepatology International · 2010 · https://doi.org/10.1007/s12072-010-9165-7

• Tumor cells disseminate early, but immunosurveillance limits metastatic outgrowth, in a mouse model of melanoma

  Journal of Clinical Investigation · 2010 · https://doi.org/10.1172/jci42002

• Management of hepatocellular carcinoma in Asia: consensus statement from the Asian Oncology Summit 2009

  The Lancet Oncology · 2009 · https://doi.org/10.1016/s1470-2045(09)70241-4

• Brivanib Alaninate, a Dual Inhibitor of Vascular Endothelial Growth Factor Receptor and Fibroblast Growth Factor Receptor Tyrosine Kinases, Induces Growth Inhibition in Mouse Models of Human Hepatocellular Carcinoma

  Clinical Cancer Research · 2008 · https://doi.org/10.1158/1078-0432.ccr-08-0509

• A Review of Mucinous Cystic Neoplasms of the Pancreas Defined by Ovarian‐type Stroma: Clinicopathological Features of 344 Patients

  World Journal of Surgery · 2006 · https://doi.org/10.1007/s00268-006-0126-1

• CT in the Preoperative Diagnosis of Fish Bone Perforation of the Gastrointestinal Tract

  American Journal of Roentgenology · 2006 · https://doi.org/10.2214/ajr.05.0178

• Perforation of the Gastrointestinal Tract Secondary to Ingestion of Foreign Bodies

  World Journal of Surgery · 2006 · https://doi.org/10.1007/s00268-005-0490-2

• Over-expression of the mitogen-activated protein kinase (MAPK) kinase (MEK)-MAPK in hepatocellular carcinoma: Its role in tumor progression and apoptosis

  BMC Gastroenterology · 2003 · https://doi.org/10.1186/1471-230x-3-19

• High-dose tamoxifen in the treatment of inoperable hepatocellular carcinoma: A multicenter randomized controlled trial

  Hepatology · 2002 · https://doi.org/10.1053/jhep.2002.36824

Current projects

No projects listed.