Frank Madeo

Research interests

Publications

• Autophagy in major human diseases

  The EMBO Journal · 2021 · https://doi.org/10.15252/embj.2021108863

• Caloric Restriction Mimetics against Age-Associated Disease: Targets, Mechanisms, and Therapeutic Potential

  Cell Metabolism · 2019 · https://doi.org/10.1016/j.cmet.2019.01.018

• Spermidine in health and disease

  Science · 2018 · https://doi.org/10.1126/science.aan2788

• Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018

  Cell Death and Differentiation · 2018 · https://doi.org/10.1038/s41418-017-0012-4

• Molecular definitions of autophagy and related processes

  The EMBO Journal · 2017 · https://doi.org/10.15252/embj.201796697

• Metabolic Control of Longevity

  Cell · 2016 · https://doi.org/10.1016/j.cell.2016.07.031

• Cardioprotection and lifespan extension by the natural polyamine spermidine

  Nature Medicine · 2016 · https://doi.org/10.1038/nm.4222

• Interventions to Slow Aging in Humans: Are We Ready?

  Aging Cell · 2015 · 10.1111/acel.12338

• Acetyl Coenzyme A: A Central Metabolite and Second Messenger

  Cell Metabolism · 2015 · https://doi.org/10.1016/j.cmet.2015.05.014

• Essential versus accessory aspects of cell death: recommendations of the NCCD 2015

  Cell Death and Differentiation · 2014 · 10.1038/cdd.2014.137

• Endogenous Hydrogen Sulfide Production Is Essential for Dietary Restriction Benefits

  Cell · 2014 · https://doi.org/10.1016/j.cell.2014.11.048

• Consensus guidelines for the detection of immunogenic cell death

  OncoImmunology · 2014 · 10.4161/21624011.2014.955691

• FAT SIGNALS - Lipases and Lipolysis in Lipid Metabolism and Signaling

  Cell Metabolism · 2012 · https://doi.org/10.1016/j.cmet.2011.12.018

• ATGL-mediated fat catabolism regulates cardiac mitochondrial function via PPAR-α and PGC-1

  Nature Medicine · 2011 · https://doi.org/10.1038/nm.2439

• Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death 2012

  Cell Death and Differentiation · 2011 · https://doi.org/10.1038/cdd.2011.96

• Caloric restriction and resveratrol promote longevity through the Sirtuin-1-dependent induction of autophagy

  Cell Death and Disease · 2010 · https://doi.org/10.1038/cddis.2009.8

• Induction of autophagy by spermidine promotes longevity

  Nature Cell Biology · 2009 · https://doi.org/10.1038/ncb1975

• Mechanisms of pre‐apoptotic calreticulin exposure in immunogenic cell death

  The EMBO Journal · 2009 · https://doi.org/10.1038/emboj.2009.1

• Guidelines for the use and interpretation of assays for monitoring cell death in higher eukaryotes

  Cell Death and Differentiation · 2009 · https://doi.org/10.1038/cdd.2009.44

• Regulation of autophagy by cytoplasmic p53

  Nature Cell Biology · 2008 · https://doi.org/10.1038/ncb1730

• Chronological aging leads to apoptosis in yeast

  The Journal of Cell Biology · 2004 · https://doi.org/10.1083/jcb.200310014

• AIF deficiency compromises oxidative phosphorylation

  The EMBO Journal · 2004 · https://doi.org/10.1038/sj.emboj.7600461

• A Caspase-Related Protease Regulates Apoptosis in Yeast

  Molecular Cell · 2002 · https://doi.org/10.1016/s1097-2765(02)00501-4

• Oxygen Stress: A Regulator of Apoptosis in Yeast

  The Journal of Cell Biology · 1999 · https://doi.org/10.1083/jcb.145.4.757

• A Yeast Mutant Showing Diagnostic Markers of Early and Late Apoptosis

  The Journal of Cell Biology · 1997 · https://doi.org/10.1083/jcb.139.3.729

Current projects

No projects listed.