Rudolf Zechner

Research interests

Publications

• Lipolysis: cellular mechanisms for lipid mobilization from fat stores

  Nature Metabolism · 2021 · https://doi.org/10.1038/s42255-021-00493-6

• Global Analysis of Plasma Lipids Identifies Liver-Derived Acylcarnitines as a Fuel Source for Brown Fat Thermogenesis

  Cell Metabolism · 2017 · https://doi.org/10.1016/j.cmet.2017.08.006

• Cytosolic lipolysis and lipophagy: two sides of the same coin

  Nature Reviews Molecular Cell Biology · 2017 · https://doi.org/10.1038/nrm.2017.76

• A Switch from White to Brown Fat Increases Energy Expenditure in Cancer-Associated Cachexia

  Cell Metabolism · 2014 · https://doi.org/10.1016/j.cmet.2014.06.011

• Biochemistry and pathophysiology of intravascular and intracellular lipolysis

  Genes & Development · 2013 · https://doi.org/10.1101/gad.209296.112

• Cellular Fatty Acid Metabolism and Cancer

  Cell Metabolism · 2013 · https://doi.org/10.1016/j.cmet.2013.05.017

• FAT SIGNALS - Lipases and Lipolysis in Lipid Metabolism and Signaling

  Cell Metabolism · 2012 · https://doi.org/10.1016/j.cmet.2011.12.018

• ATGL-mediated fat catabolism regulates cardiac mitochondrial function via PPAR-α and PGC-1

  Nature Medicine · 2011 · https://doi.org/10.1038/nm.2439

• Adipose Triglyceride Lipase Contributes to Cancer-Associated Cachexia

  Science · 2011 · https://doi.org/10.1126/science.1198973

• Recommended nomenclature for five mammalian carboxylesterase gene families: human, mouse, and rat genes and proteins

  Mammalian Genome · 2010 · https://doi.org/10.1007/s00335-010-9284-4

• Lipolysis – A highly regulated multi-enzyme complex mediates the catabolism of cellular fat stores

  Progress in Lipid Research · 2010 · https://doi.org/10.1016/j.plipres.2010.10.004

• Weight loss and lipolysis promote a dynamic immune response in murine adipose tissue

  Journal of Clinical Investigation · 2010 · https://doi.org/10.1172/jci42845

• Adipose triglyceride lipase and the lipolytic catabolism of cellular fat stores

  Journal of Lipid Research · 2008 · https://doi.org/10.1194/jlr.r800031-jlr200

• Adipose Triglyceride Lipase and Hormone-sensitive Lipase Are the Major Enzymes in Adipose Tissue Triacylglycerol Catabolism

  Journal of Biological Chemistry · 2006 · https://doi.org/10.1074/jbc.m608048200

• Adipose triglyceride lipase-mediated lipolysis of cellular fat stores is activated by CGI-58 and defective in Chanarin-Dorfman Syndrome

  Cell Metabolism · 2006 · https://doi.org/10.1016/j.cmet.2006.03.005

• Defective Lipolysis and Altered Energy Metabolism in Mice Lacking Adipose Triglyceride Lipase

  Science · 2006 · https://doi.org/10.1126/science.1123965

• Fat Mobilization in Adipose Tissue Is Promoted by Adipose Triglyceride Lipase

  Science · 2004 · https://doi.org/10.1126/science.1100747

• Hormone-sensitive Lipase Deficiency in Mice Causes Diglyceride Accumulation in Adipose Tissue, Muscle, and Testis

  Journal of Biological Chemistry · 2002 · https://doi.org/10.1074/jbc.m110355200

• Mechanism of hypertriglyceridemia in human apolipoprotein (apo) CIII transgenic mice. Diminished very low density lipoprotein fractional catabolic rate associated with increased apo CIII and reduced apo E on the particles.

  Journal of Clinical Investigation · 1992 · https://doi.org/10.1172/jci116066

Current projects

No projects listed.