Keith W. Kelley

Research interests

Publications

• Stress-induced epinephrine enhances lactate dehydrogenase A and promotes breast cancer stem-like cells

  Journal of Clinical Investigation · 2019 · 10.1172/jci121685

• Aurora‐A Kinase: A Potent Oncogene and Target for Cancer Therapy

  Medicinal Research Reviews · 2016 · 10.1002/med.21399

• NMDA Receptor Blockade by Ketamine Abrogates Lipopolysaccharide-Induced Depressive-Like Behavior in C57BL/6J Mice

  Neuropsychopharmacology · 2013 · 10.1038/npp.2013.71

• Immune–neural connections: how the immune system’s response to infectious agents influences behavior

  Journal of Experimental Biology · 2012 · 10.1242/jeb.073411

• Inflammation-associated depression: From serotonin to kynurenine

  Psychoneuroendocrinology · 2010 · 10.1016/j.psyneuen.2010.09.012

• CSF concentrations of brain tryptophan and kynurenines during immune stimulation with IFN-α: relationship to CNS immune responses and depression

  Molecular Psychiatry · 2009 · 10.1038/mp.2009.116

• Induction of IDO by Bacille Calmette-Guérin Is Responsible for Development of Murine Depressive-Like Behavior

  The Journal of Immunology · 2009 · 10.4049/jimmunol.0802722

• Interferon-γ and Tumor Necrosis Factor-α Mediate the Upregulation of Indoleamine 2,3-Dioxygenase and the Induction of Depressive-Like Behavior in Mice in Response to Bacillus Calmette-Guérin

  Journal of Neuroscience · 2009 · 10.1523/jneurosci.5032-08.2009

• NIH public access policy

  Brain Behavior and Immunity · 2008 · 10.1016/j.bbi.2008.05.010

• Regulation of IGF-I function by proinflammatory cytokines: At the interface of immunology and endocrinology

  Cellular Immunology · 2008 · 10.1016/j.cellimm.2007.09.010

• Lipopolysaccharide-induced depressive-like behavior is mediated by indoleamine 2,3-dioxygenase activation in mice

  Molecular Psychiatry · 2008 · https://doi.org/10.1038/sj.mp.4002148

• Luteolin reduces IL-6 production in microglia by inhibiting JNK phosphorylation and activation of AP-1

  Proceedings of the National Academy of Sciences · 2008 · 10.1073/pnas.0802865105

• From inflammation to sickness and depression: when the immune system subjugates the brain

  Nature reviews. Neuroscience · 2007 · https://doi.org/10.1038/nrn2297

• Lipopolysaccharide induces delayed FosB/DeltaFosB immunostaining within the mouse extended amygdala, hippocampus and hypothalamus, that parallel the expression of depressive-like behavior

  Psychoneuroendocrinology · 2007 · 10.1016/j.psyneuen.2007.03.005

• Aging Exacerbates Depressive-like Behavior in Mice in Response to Activation of the Peripheral Innate Immune System

  Neuropsychopharmacology · 2007 · 10.1038/sj.npp.1301649

• Twenty years of research on cytokine-induced sickness behavior

  Brain Behavior and Immunity · 2006 · https://doi.org/10.1016/j.bbi.2006.09.006

• Exaggerated neuroinflammation and sickness behavior in aged mice after activation of the peripheral innate immune system

  The FASEB Journal · 2005 · https://doi.org/10.1096/fj.05-3776fje

• Cytokine-induced sickness behavior

  Brain Behavior and Immunity · 2003 · 10.1016/s0889-1591(02)00077-6

• Endogenous brain IL-1 mediates LPS-induced anorexia and hypothalamic cytokine expression

  American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · 2000 · 10.1152/ajpregu.2000.279.1.r93

• Temporal and spatial relationships between lipopolysaccharide-induced expression of fos, interleukin-1 β and inducible nitric oxide synthase in rat brain

  Neuroscience · 1999 · https://doi.org/10.1016/s0306-4522(98)00368-6

• Lipopolysaccharide induces sickness behaviour in rats by a vagal mediated mechanism.

  PubMed · 1994

• Effects of interleukin-1 receptor antagonist on the behavioral effects of lipopolysaccharide in rat

  Brain Research · 1992 · 10.1016/0006-8993(92)90779-9

• Growth hormone, lymphocytes and macrophages

  Biochemical Pharmacology · 1989 · https://doi.org/10.1016/0006-2952(89)90222-0

• GH3 pituitary adenoma cells can reverse thymic aging in rats.

  Proceedings of the National Academy of Sciences · 1986 · 10.1073/pnas.83.15.5663

• Stress and immune function: a bibliographic review.

  PubMed · 1980

Current projects

No projects listed.