Roland Eils

Research interests

Publications

• Characterizing genetic intra-tumor heterogeneity across 2,658 human cancer genomes

  Cell · 2021 · https://doi.org/10.1016/j.cell.2021.03.009

• Olfactory transmucosal SARS-CoV-2 invasion as a port of central nervous system entry in individuals with COVID-19

  Nature Neuroscience · 2020 · https://doi.org/10.1038/s41593-020-00758-5

• SARS‐CoV‐2 receptor ACE2 and TMPRSS2 are primarily expressed in bronchial transient secretory cells

  The EMBO Journal · 2020 · 10.15252/embj.20105114

• The evolutionary history of 2,658 cancers

  Nature · 2020 · https://doi.org/10.1038/s41586-019-1907-7

• COVID-19 severity correlates with airway epithelium–immune cell interactions identified by single-cell analysis

  Nature Biotechnology · 2020 · https://doi.org/10.1038/s41587-020-0602-4

• The landscape of viral associations in human cancers

  Nature Genetics · 2020 · https://doi.org/10.1038/s41588-019-0558-9

• The landscape of genomic alterations across childhood cancers

  Nature · 2018 · https://doi.org/10.1038/nature25480

• The Human Cell Atlas

  eLife · 2017 · 10.7554/elife.27041

• The whole-genome landscape of medulloblastoma subtypes

  Nature · 2017 · 10.1038/nature22973

• The International Human Epigenome Consortium: A Blueprint for Scientific Collaboration and Discovery

  Cell · 2016 · https://doi.org/10.1016/j.cell.2016.11.007

• Atypical Teratoid/Rhabdoid Tumors Are Comprised of Three Epigenetic Subgroups with Distinct Enhancer Landscapes

  Cancer Cell · 2016 · 10.1016/j.ccell.2016.02.001

• Complex heatmaps reveal patterns and correlations in multidimensional genomic data

  Bioinformatics · 2016 · https://doi.org/10.1093/bioinformatics/btw313

• Identification of Regulatory Networks in HSCs and Their Immediate Progeny via Integrated Proteome, Transcriptome, and DNA Methylome Analysis

  Cell stem cell · 2014 · 10.1016/j.stem.2014.07.005

• circlize implements and enhances circular visualization in R

  Bioinformatics · 2014 · https://doi.org/10.1093/bioinformatics/btu393

• Genome Sequencing of SHH Medulloblastoma Predicts Genotype-Related Response to Smoothened Inhibition

  Cancer Cell · 2014 · 10.1016/j.ccr.2014.02.004

• Enhancer hijacking activates GFI1 family oncogenes in medulloblastoma

  Nature · 2014 · 10.1038/nature13379

• Epigenomic alterations define lethal CIMP-positive ependymomas of infancy

  Nature · 2014 · 10.1038/nature13108

• Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma

  Nature Genetics · 2013 · 10.1038/ng.2682

• Signatures of mutational processes in human cancer

  Nature · 2013 · https://doi.org/10.1038/nature12477

• Genome Sequencing of Pediatric Medulloblastoma Links Catastrophic DNA Rearrangements with TP53 Mutations

  Cell · 2012 · 10.1016/j.cell.2011.12.013

• Dissecting the genomic complexity underlying medulloblastoma

  Nature · 2012 · 10.1038/nature11284

• The MicroArray Quality Control (MAQC)-II study of common practices for the development and validation of microarray-based predictive models

  Nature Biotechnology · 2010 · 10.1038/nbt.1665

• Phenotypic profiling of the human genome by time-lapse microscopy reveals cell division genes

  Nature · 2010 · 10.1038/nature08869

• Omic data from evolved E. coli are consistent with computed optimal growth from genome‐scale models

  Molecular Systems Biology · 2010 · 10.1038/msb.2010.47

• Systemic Spread Is an Early Step in Breast Cancer

  Cancer Cell · 2008 · 10.1016/j.ccr.2007.12.003

• Three-Dimensional Maps of All Chromosomes in Human Male Fibroblast Nuclei and Prometaphase Rosettes

  PLoS Biology · 2005 · 10.1371/journal.pbio.0030157

• From latent disseminated cells to overt metastasis: Genetic analysis of systemic breast cancer progression

  Proceedings of the National Academy of Sciences · 2003 · 10.1073/pnas.1331931100

Current projects

No projects listed.