Jun Ren

Research interests

Publications

• Inflammation in atherosclerosis: pathophysiology and mechanisms

  Cell Death and Disease · 2024 · 10.1038/s41419-024-07166-8

• Mitophagy in cardiovascular diseases: molecular mechanisms, pathogenesis, and treatment

  Trends in Molecular Medicine · 2022 · 10.1016/j.molmed.2022.06.007

• Mitochondrial quality control mechanisms as therapeutic targets in doxorubicin-induced cardiotoxicity

  Trends in Pharmacological Sciences · 2022 · 10.1016/j.tips.2022.10.003

• ER stress and UPR in Alzheimer’s disease: mechanisms, pathogenesis, treatments

  Cell Death and Disease · 2022 · 10.1038/s41419-022-05153-5

• Endoplasmic reticulum stress in liver diseases

  Hepatology · 2022 · 10.1002/hep.32562

• Endoplasmic reticulum stress and unfolded protein response in cardiovascular diseases

  Nature Reviews Cardiology · 2021 · https://doi.org/10.1038/s41569-021-00511-w

• Obesity cardiomyopathy: evidence, mechanisms, and therapeutic implications

  Physiological Reviews · 2021 · 10.1152/physrev.00030.2020

• Ferritinophagy and ferroptosis in the management of metabolic diseases

  Trends in Endocrinology and Metabolism · 2021 · 10.1016/j.tem.2021.04.010

• Targeting autophagy in ischemic stroke: From molecular mechanisms to clinical therapeutics

  Pharmacology & Therapeutics · 2021 · 10.1016/j.pharmthera.2021.107848

• Role of mitochondrial quality surveillance in myocardial infarction: From bench to bedside

  Ageing Research Reviews · 2020 · 10.1016/j.arr.2020.101250

• Pathogenesis of cardiac ischemia reperfusion injury is associated with CK2α-disturbed mitochondrial homeostasis via suppression of FUNDC1-related mitophagy

  Cell Death and Differentiation · 2018 · 10.1038/s41418-018-0086-7

• Targeting Autophagy in Aging and Aging-Related Cardiovascular Diseases

  Trends in Pharmacological Sciences · 2018 · 10.1016/j.tips.2018.10.005

• RETRACTED ARTICLE: NR4A1 aggravates the cardiac microvascular ischemia reperfusion injury through suppressing FUNDC1-mediated mitophagy and promoting Mff-required mitochondrial fission by CK2α

  Basic Research in Cardiology · 2018 · 10.1007/s00395-018-0682-1

• Targeting autophagy in obesity: from pathophysiology to management

  Nature Reviews Endocrinology · 2018 · 10.1038/s41574-018-0009-1

• RETRACTED: Effects of melatonin on fatty liver disease: The role of NR 4A1/ DNA ‐ PK cs/p53 pathway, mitochondrial fission, and mitophagy

  Journal of Pineal Research · 2017 · 10.1111/jpi.12450

• Empagliflozin rescues diabetic myocardial microvascular injury via AMPK-mediated inhibition of mitochondrial fission

  Redox Biology · 2017 · https://doi.org/10.1016/j.redox.2017.12.019

• Ripk3 induces mitochondrial apoptosis via inhibition of FUNDC1 mitophagy in cardiac IR injury

  Redox Biology · 2017 · 10.1016/j.redox.2017.07.007

• DUSP1 alleviates cardiac ischemia/reperfusion injury by suppressing the Mff-required mitochondrial fission and Bnip3-related mitophagy via the JNK pathways

  Redox Biology · 2017 · 10.1016/j.redox.2017.11.004

• Capsaicin induces browning of white adipose tissue and counters obesity by activating TRPV1 channel‐dependent mechanisms

  British Journal of Pharmacology · 2016 · 10.1111/bph.13514

• Mitochondrial biogenesis in the metabolic syndrome and cardiovascular disease

  Journal of Molecular Medicine · 2010 · 10.1007/s00109-010-0663-9

• Aldehyde dehydrogenase 2 (ALDH2) rescues myocardial ischaemia/reperfusion injury: role of autophagy paradox and toxic aldehyde

  European Heart Journal · 2010 · 10.1093/eurheartj/ehq253

• Loss of MeCP2 in aminergic neurons causes cell-autonomous defects in neurotransmitter synthesis and specific behavioral abnormalities

  Proceedings of the National Academy of Sciences · 2009 · 10.1073/pnas.0912257106

• High dietary fat induces NADPH oxidase-associated oxidative stress and inflammation in rat cerebral cortex

  Experimental Neurology · 2004 · 10.1016/j.expneurol.2004.10.011

• Leptin and hyperleptinemia - from friend to foe for cardiovascular function

  Journal of Endocrinology · 2004 · 10.1677/joe.0.1810001

• Insulin-like Growth Factor I as aÈCardiac Hormone: Physiological and Pathophysiological Implications in Heart Disease

  Journal of Molecular and Cellular Cardiology · 1999 · 10.1006/jmcc.1999.1036

Current projects

No projects listed.