Takahiro Ochiya

Research interests

Publications

• Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches

  Journal of Extracellular Vesicles · 2024 · https://doi.org/10.1002/jev2.12404

• Updating MISEV: Evolving the minimal requirements for studies of extracellular vesicles

  Journal of Extracellular Vesicles · 2021 · 10.1002/jev2.12182

• Extracellular vesicles as biomarkers and therapeutic targets for cancer

  American Journal of Physiology-Cell Physiology · 2019 · 10.1152/ajpcell.00280.2019

• Emerging roles of long non‐coding RNA in cancer

  Cancer Science · 2018 · 10.1111/cas.13642

• Malignant extracellular vesicles carrying MMP1 mRNA facilitate peritoneal dissemination in ovarian cancer

  Nature Communications · 2017 · 10.1038/ncomms14470

• Drug Resistance Driven by Cancer Stem Cells and Their Niche

  International Journal of Molecular Sciences · 2017 · 10.3390/ijms18122574

• Versatile roles of extracellular vesicles in cancer

  Journal of Clinical Investigation · 2016 · 10.1172/jci81130

• Novel combination of serum microRNA for detecting breast cancer in the early stage

  Cancer Science · 2016 · 10.1111/cas.12880

• Exosomal microRNA in serum is a novel biomarker of recurrence in human colorectal cancer

  British Journal of Cancer · 2015 · 10.1038/bjc.2015.201

• Bovine milk exosomes contain microRNA and mRNA and are taken up by human macrophages

  Journal of Dairy Science · 2015 · 10.3168/jds.2014-9076

• Applying extracellular vesicles based therapeutics in clinical trials – an ISEV position paper

  Journal of Extracellular Vesicles · 2015 · https://doi.org/10.3402/jev.v4.30087

• Brain metastatic cancer cells release microRNA-181c-containing extracellular vesicles capable of destructing blood–brain barrier

  Nature Communications · 2015 · https://doi.org/10.1038/ncomms7716

• Exosomes from bone marrow mesenchymal stem cells contain a microRNA that promotes dormancy in metastatic breast cancer cells

  Science Signaling · 2014 · 10.1126/scisignal.2005231

• Ultra-sensitive liquid biopsy of circulating extracellular vesicles using ExoScreen

  Nature Communications · 2014 · 10.1038/ncomms4591

• Neutral Sphingomyelinase 2 (nSMase2)-dependent Exosomal Transfer of Angiogenic MicroRNAs Regulate Cancer Cell Metastasis

  Journal of Biological Chemistry · 2013 · 10.1074/jbc.m112.446831

• Human adipose tissue-derived mesenchymal stem cells secrete functional neprilysin-bound exosomes

  Scientific Reports · 2013 · 10.1038/srep01197

• The therapeutic potential of mesenchymal stem cell‐derived extracellular vesicles

  PROTEOMICS · 2013 · 10.1002/pmic.201200373

• Comparative marker analysis of extracellular vesicles in different human cancer types

  Journal of Extracellular Vesicles · 2013 · 10.3402/jev.v2i0.20424

• Bovine milk contains microRNA and messenger RNA that are stable under degradative conditions

  Journal of Dairy Science · 2012 · 10.3168/jds.2012-5489

• Systemically Injected Exosomes Targeted to EGFR Deliver Antitumor MicroRNA to Breast Cancer Cells

  Molecular Therapy · 2012 · https://doi.org/10.1038/mt.2012.180

• Secretory Mechanisms and Intercellular Transfer of MicroRNAs in Living Cells

  Journal of Biological Chemistry · 2010 · https://doi.org/10.1074/jbc.m110.107821

• microRNA as a new immune-regulatory agent in breast milk

  Silence · 2010 · 10.1186/1758-907x-1-7

• Circulating microRNA in body fluid: a new potential biomarker for cancer diagnosis and prognosis

  Cancer Science · 2010 · https://doi.org/10.1111/j.1349-7006.2010.01650.x

• Systemic Delivery of Synthetic MicroRNA-16 Inhibits the Growth of Metastatic Prostate Tumors via Downregulation of Multiple Cell-cycle Genes

  Molecular Therapy · 2009 · 10.1038/mt.2009.207

• Adipose tissue-derived mesenchymal stem cells as a source of human hepatocytes

  Hepatology · 2007 · 10.1002/hep.21704

Current projects

No projects listed.