Haruhiko Koseki

Research interests

Publications

• Functional annotation of human long noncoding RNAs via molecular phenotyping

  Genome Research · 2020 · https://doi.org/10.1101/gr.254219.119

• FANTOM5 CAGE profiles of human and mouse samples

  Scientific Data · 2017 · https://doi.org/10.1038/sdata.2017.112

• Immunoresponsive Gene 1 and Itaconate Inhibit Succinate Dehydrogenase to Modulate Intracellular Succinate Levels

  Journal of Biological Chemistry · 2016 · https://doi.org/10.1074/jbc.m115.685792

• Transcribed enhancers lead waves of coordinated transcription in transitioning mammalian cells

  Science · 2015 · https://doi.org/10.1126/science.1259418

• Variant PRC1 Complex-Dependent H2A Ubiquitylation Drives PRC2 Recruitment and Polycomb Domain Formation

  Cell · 2014 · https://doi.org/10.1016/j.cell.2014.05.004

• Generation of Rejuvenated Antigen-Specific T Cells by Reprogramming to Pluripotency and Redifferentiation

  Cell stem cell · 2013 · https://doi.org/10.1016/j.stem.2012.11.002

• Commensal microbe-derived butyrate induces the differentiation of colonic regulatory T cells

  Nature · 2013 · https://doi.org/10.1038/nature12721

• SF3B1 haploinsufficiency leads to formation of ring sideroblasts in myelodysplastic syndromes

  Blood · 2012 · https://doi.org/10.1182/blood-2012-05-430876

• KDM2B links the Polycomb Repressive Complex 1 (PRC1) to recognition of CpG islands

  eLife · 2012 · https://doi.org/10.7554/elife.00205

• The Zinc Transporter SLC39A13/ZIP13 Is Required for Connective Tissue Development; Its Involvement in BMP/TGF-β Signaling Pathways

  PLoS ONE · 2008 · https://doi.org/10.1371/journal.pone.0003642

• Genomewide Analysis of PRC1 and PRC2 Occupancy Identifies Two Classes of Bivalent Domains

  PLoS Genetics · 2008 · https://doi.org/10.1371/journal.pgen.1000242

• Ring1-mediated ubiquitination of H2A restrains poised RNA polymerase II at bivalent genes in mouse ES cells

  Nature Cell Biology · 2007 · https://doi.org/10.1038/ncb1663

• The SRA protein Np95 mediates epigenetic inheritance by recruiting Dnmt1 to methylated DNA

  Nature · 2007 · https://doi.org/10.1038/nature06397

• Control of Developmental Regulators by Polycomb in Human Embryonic Stem Cells

  Cell · 2006 · https://doi.org/10.1016/j.cell.2006.02.043

• Enhanced Self-Renewal of Hematopoietic Stem Cells Mediated by the Polycomb Gene Product Bmi-1

  Immunity · 2004 · https://doi.org/10.1016/j.immuni.2004.11.004

• Polycomb Group Proteins Ring1A/B Link Ubiquitylation of Histone H2A to Heritable Gene Silencing and X Inactivation

  Developmental Cell · 2004 · https://doi.org/10.1016/j.devcel.2004.10.005

• Natural killer-like nonspecific tumor cell lysis mediated by specific ligand-activated Vα14 NKT cells

  Proceedings of the National Academy of Sciences · 1998 · https://doi.org/10.1073/pnas.95.10.5690

• Requirement for V α 14 NKT Cells in IL-12-Mediated Rejection of Tumors

  Science · 1997 · https://doi.org/10.1126/science.278.5343.1623

• CD1d-Restricted and TCR-Mediated Activation of V α 14 NKT Cells by Glycosylceramides

  Science · 1997 · https://doi.org/10.1126/science.278.5343.1626

Current projects

No projects listed.