John L. Hopper

Research interests

Publications

• Avoiding dynastic, assortative mating, and population stratification biases in Mendelian randomization through within-family analyses

  Nature Communications · 2020 · 10.1038/s41467-020-17117-4

• Avoiding dynastic, assortative mating, and population stratification biases in Mendelian randomization through within-family analyses

  Nature Communications · 2020 · 10.1038/s41467-020-17117-4

• Cancer risks by gene, age, and gender in 6350 carriers of pathogenic mismatch repair variants: findings from the Prospective Lynch Syndrome Database

  Genetics in Medicine · 2019 · https://doi.org/10.1038/s41436-019-0596-9

• Cancer Risks Associated With GermlinePALB2Pathogenic Variants: An International Study of 524 Families

  Journal of Clinical Oncology · 2019 · 10.1200/jco.19.01907

• Childhood predictors of lung function trajectories and future COPD risk: a prospective cohort study from the first to the sixth decade of life

  The Lancet Respiratory Medicine · 2018 · 10.1016/s2213-2600(18)30100-0

• Discovery of common and rare genetic risk variants for colorectal cancer

  Nature Genetics · 2018 · https://doi.org/10.1038/s41588-018-0286-6

• Risks of Breast, Ovarian, and Contralateral Breast Cancer for BRCA1 and BRCA2 Mutation Carriers

  JAMA · 2017 · https://doi.org/10.1001/jama.2017.7112

• Prevalence and Penetrance of Major Genes and Polygenes for Colorectal Cancer

  Cancer Epidemiology Biomarkers & Prevention · 2016 · 10.1158/1055-9965.epi-16-0693

• Identification of Lynch Syndrome Among Patients With Colorectal Cancer

  JAMA · 2012 · 10.1001/jama.2012.13088

• A novel recurrent mutation in MITF predisposes to familial and sporadic melanoma

  Nature · 2011 · 10.1038/nature10630

• Genome-wide association study identifies three loci associated with melanoma risk

  Nature Genetics · 2009 · 10.1038/ng.411

• The Clinical Phenotype of Lynch Syndrome Due to Germ-Line PMS2 Mutations

  Gastroenterology · 2008 · 10.1053/j.gastro.2008.04.026

• Multiple newly identified loci associated with prostate cancer susceptibility

  Nature Genetics · 2008 · https://doi.org/10.1038/ng.90

• A genome-wide association study identifies colorectal cancer susceptibility loci on chromosomes 10p14 and 8q23.3

  Nature Genetics · 2008 · 10.1038/ng.111

• Iron-Overload–Related Disease inHFEHereditary Hemochromatosis

  New England Journal of Medicine · 2008 · https://doi.org/10.1056/nejmoa073286

• The BOADICEA model of genetic susceptibility to breast and ovarian cancers: updates and extensions

  British Journal of Cancer · 2008 · https://doi.org/10.1038/sj.bjc.6604305

• Mammographic breast density as an intermediate phenotype for breast cancer

  The Lancet Oncology · 2005 · 10.1016/s1470-2045(05)70390-9

• Lower Cancer Incidence in Amsterdam-I Criteria Families Without Mismatch Repair Deficiency

  JAMA · 2005 · 10.1001/jama.293.16.1979

• Heritability of Mammographic Density, a Risk Factor for Breast Cancer

  New England Journal of Medicine · 2002 · 10.1056/nejmoa013390

• Immunohistochemistry Versus Microsatellite Instability Testing in Phenotyping Colorectal Tumors

  Journal of Clinical Oncology · 2002 · 10.1200/jco.2002.20.4.1043

• Preoperative MRI predicts outcome of temporal lobectomy

  Neurology · 1995 · 10.1212/wnl.45.7.1358

• Genetics of Asthma and Hay Fever in Australian Twins

  American Review of Respiratory Disease · 1990 · 10.1164/ajrccm/142.6_pt_1.1351

• Reduced Bone Mass in Daughters of Women with Osteoporosis

  New England Journal of Medicine · 1989 · 10.1056/nejm198903023200903

• Genetic determinants of bone mass in adults. A twin study.

  Journal of Clinical Investigation · 1987 · https://doi.org/10.1172/jci113125

• Extensions to multivariate normal models for pedigree analysis

  Annals of Human Genetics · 1982 · 10.1111/j.1469-1809.1982.tb01588.x

Current projects

No projects listed.