Han‐Ming Shen

Research interests

Publications

• Macrophage plasticity: signaling pathways, tissue repair, and regeneration

  MedComm · 2024 · 10.1002/mco2.658

• Amelioration of Alzheimer’s disease pathology by mitophagy inducers identified via machine learning and a cross-species workflow

  Nature Biomedical Engineering · 2022 · 10.1038/s41551-021-00819-5

• The emerging mechanisms and functions of microautophagy

  Nature Reviews Molecular Cell Biology · 2022 · 10.1038/s41580-022-00529-z

• Celastrol induces ferroptosis in activated HSCs to ameliorate hepatic fibrosis via targeting peroxiredoxins and HO-1

  Acta Pharmaceutica Sinica B · 2021 · 10.1016/j.apsb.2021.12.007

• Mito‐Bomb: Targeting Mitochondria for Cancer Therapy

  Advanced Materials · 2021 · 10.1002/adma.202007778

• Full-coverage regulations of autophagy by ROS: from induction to maturation

  Autophagy · 2021 · 10.1080/15548627.2021.1984656

• Targeting the Endocytic Pathway and Autophagy Process as a Novel Therapeutic Strategy in COVID-19

  International Journal of Biological Sciences · 2020 · 10.7150/ijbs.45498

• Dual role of autophagy in hallmarks of cancer

  Oncogene · 2017 · https://doi.org/10.1038/s41388-017-0046-6

• Long non-coding RNA linc00673 regulated non-small cell lung cancer proliferation, migration, invasion and epithelial mesenchymal transition by sponging miR-150-5p

  Molecular Cancer · 2017 · 10.1186/s12943-017-0685-9

• AMPK-Dependent Phosphorylation of GAPDH Triggers Sirt1 Activation and Is Necessary for Autophagy upon Glucose Starvation

  Molecular Cell · 2015 · 10.1016/j.molcel.2015.10.037

• Haem-activated promiscuous targeting of artemisinin in Plasmodium falciparum

  Nature Communications · 2015 · https://doi.org/10.1038/ncomms10111

• At the end of the autophagic road: an emerging understanding of lysosomal functions in autophagy

  Trends in Biochemical Sciences · 2013 · 10.1016/j.tibs.2013.12.001

• Activation of lysosomal function in the course of autophagy via mTORC1 suppression and autophagosome-lysosome fusion

  Cell Research · 2013 · 10.1038/cr.2013.11

• Design and Synthesis of Minimalist Terminal Alkyne‐Containing Diazirine Photo‐Crosslinkers and Their Incorporation into Kinase Inhibitors for Cell‐ and Tissue‐Based Proteome Profiling

  Angewandte Chemie International Edition · 2013 · 10.1002/anie.201300683

• Autophagic cell death: Loch Ness monster or endangered species?

  Autophagy · 2011 · 10.4161/auto.7.5.14226

• Dual Role of 3-Methyladenine in Modulation of Autophagy via Different Temporal Patterns of Inhibition on Class I and III Phosphoinositide 3-Kinase

  Journal of Biological Chemistry · 2010 · https://doi.org/10.1074/jbc.m109.080796

• NFκB signaling in carcinogenesis and as a potential molecular target for cancer therapy

  APOPTOSIS · 2009 · 10.1007/s10495-009-0315-0

• Luteolin, a Flavonoid with Potential for Cancer Prevention and Therapy

  Current Cancer Drug Targets · 2008 · https://doi.org/10.2174/156800908786241050

• Anti‐cancer properties of anthraquinones from rhubarb

  Medicinal Research Reviews · 2006 · 10.1002/med.20094

• TNF receptor superfamily‐induced cell death: redox‐dependent execution

  The FASEB Journal · 2006 · 10.1096/fj.05-5603rev

• Anti-Cancer Potential of Sesquiterpene Lactones: Bioactivity and Molecular Mechanisms

  Anti-Cancer Agents in Medicinal Chemistry · 2005 · 10.2174/1568011053765976

• JNK signaling pathway is a key modulator in cell death mediated by reactive oxygen and nitrogen species

  Free Radical Biology and Medicine · 2005 · https://doi.org/10.1016/j.freeradbiomed.2005.10.056

• Tumor Necrosis Factor-induced Nonapoptotic Cell Death Requires Receptor-interacting Protein-mediated Cellular Reactive Oxygen Species Accumulation

  Journal of Biological Chemistry · 2004 · 10.1074/jbc.m313141200

• Critical roles of intracellular thiols and calcium in parthenolide-induced apoptosis in human colorectal cancer cells

  Cancer Letters · 2004 · 10.1016/j.canlet.2003.11.028

• Detection of elevated reactive oxygen species level in cultured rat hepatocytes treated with aflatoxin B1

  Free Radical Biology and Medicine · 1996 · 10.1016/0891-5849(96)00019-6

Current projects

No projects listed.