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Choon Nam Ong

Researcher Next ID · RN-025752

Researcher · Biochemistry, Genetics and Molecular Biology

National University of Singapore

Singapore, Singapore

Not currently recruitingFunding unknown
Works count
503
Citation count
30,359
H-index
95
i10-index
349

Research interests

Biochemistry, Genetics and Molecular Biology
Environmental Science
Medicine
Metabolomics and Mass Spectrometry Studies
Heavy Metal Exposure and Toxicity
Carcinogens and Genotoxicity Assessment
Antioxidant Activity and Oxidative Stress
Genomics, phytochemicals, and oxidative stress

Publications

  • Zinc oxide nanoparticles exhibit cytotoxicity and genotoxicity through oxidative stress responses in human lung fibroblasts and Drosophila melanogaster

    International Journal of Nanomedicine · 2017 · 10.2147/ijn.s124403

  • Degradation of the Common Aqueous Antibiotic Tetracycline using a Carbon Nanotube Electrochemical Filter

    Environmental Science & Technology · 2015 · 10.1021/acs.est.5b00870

  • HILIC‐MS for metabolomics: An attractive and complementary approach to RPLC‐MS

    Mass Spectrometry Reviews · 2014 · 10.1002/mas.21445

  • Metabolic Signature Shift in Type 2 Diabetes Mellitus Revealed by Mass Spectrometry-based Metabolomics

    The Journal of Clinical Endocrinology & Metabolism · 2013 · 10.1210/jc.2012-4132

  • Significant Biochemical, Biophysical and Metabolic Diversity in Circulating Human Cord Blood Reticulocytes

    PLoS ONE · 2013 · https://doi.org/10.1371/journal.pone.0076062

  • Highly luminescent silver nanoclusters with tunable emissions: cyclic reduction–decomposition synthesis and antimicrobial properties

    NPG Asia Materials · 2013 · 10.1038/am.2013.3

  • Titanium dioxide nanomaterials cause endothelial cell leakiness by disrupting the homophilic interaction of VE–cadherin

    Nature Communications · 2013 · 10.1038/ncomms2655

  • Dual Role of 3-Methyladenine in Modulation of Autophagy via Different Temporal Patterns of Inhibition on Class I and III Phosphoinositide 3-Kinase

    Journal of Biological Chemistry · 2010 · https://doi.org/10.1074/jbc.m109.080796

  • Autophagy and oxidative stress associated with gold nanoparticles

    Biomaterials · 2010 · 10.1016/j.biomaterials.2010.04.014

  • Characterization, purification, and stability of gold nanoparticles

    Biomaterials · 2010 · 10.1016/j.biomaterials.2010.08.012

  • Antioxidant activity and profiles of common fruits in Singapore

    Food Chemistry · 2010 · 10.1016/j.foodchem.2010.04.002

  • Microdevice for the isolation and enumeration of cancer cells from blood

    Biomedical Microdevices · 2009 · 10.1007/s10544-009-9305-9

  • Biodistribution of gold nanoparticles and gene expression changes in the liver and spleen after intravenous administration in rats

    Biomaterials · 2009 · 10.1016/j.biomaterials.2009.11.079

  • Activation of the PI3K-Akt-mTOR signaling pathway promotes necrotic cell death via suppression of autophagy

    Autophagy · 2009 · 10.4161/auto.9099

  • Deformability study of breast cancer cells using microfluidics

    Biomedical Microdevices · 2008 · 10.1007/s10544-008-9262-8

  • AFM indentation study of breast cancer cells

    Biochemical and Biophysical Research Communications · 2008 · https://doi.org/10.1016/j.bbrc.2008.07.078

  • Workgroup Report: Public Health Strategies for Reducing Aflatoxin Exposure in Developing Countries

    Environmental Health Perspectives · 2006 · https://doi.org/10.1289/ehp.9302

  • Anti‐cancer properties of anthraquinones from rhubarb

    Medicinal Research Reviews · 2006 · 10.1002/med.20094

  • Anti-Cancer Potential of Sesquiterpene Lactones: Bioactivity and Molecular Mechanisms

    Anti-Cancer Agents in Medicinal Chemistry · 2005 · 10.2174/1568011053765976

  • Critical roles of intracellular thiols and calcium in parthenolide-induced apoptosis in human colorectal cancer cells

    Cancer Letters · 2004 · 10.1016/j.canlet.2003.11.028

  • Role of oxidative stress and mitochondrial changes in cyanobacteria-induced apoptosis and hepatotoxicity

    FEMS Microbiology Letters · 2003 · 10.1016/s0378-1097(03)00100-9

  • Comparison of Zinc Concentrations in Blood and Seminal Plasma and the Various Sperm Parameters Between Fertile and Infertile Men

    Journal of Andrology · 2000 · 10.1002/j.1939-4640.2000.tb03275.x

  • Detection of oxidative DNA damage in human sperm and its association with sperm function and male infertility

    Free Radical Biology and Medicine · 2000 · 10.1016/s0891-5849(99)00234-8

  • Critical Role of Reactive Oxygen Species and Mitochondrial Permeability Transition in Microcystin-Induced Rapid Apoptosis in Rat Hepatocytes

    Hepatology · 2000 · 10.1053/jhep.2000.16183

  • Detection of elevated reactive oxygen species level in cultured rat hepatocytes treated with aflatoxin B1

    Free Radical Biology and Medicine · 1996 · 10.1016/0891-5849(96)00019-6

  • Statistical evaluation of agreement between two methods for measuring a quantitative variable

    Computers in Biology and Medicine · 1989 · 10.1016/0010-4825(89)90036-x

Current projects

    No projects listed.