Manolis Kellis

Research interests

Publications

• GENCODE: reference annotation for the human and mouse genomes in 2023

  Nucleic Acids Research · 2022 · https://doi.org/10.1093/nar/gkac1071

• The impact of sex on gene expression across human tissues

  Science · 2020 · https://doi.org/10.1126/science.aba3066

• Determinants of telomere length across human tissues

  Science · 2020 · https://doi.org/10.1126/science.aaz6876

• GENCODE 2021

  Nucleic Acids Research · 2020 · https://doi.org/10.1093/nar/gkaa1087

• Analyses of non-coding somatic drivers in 2,658 cancer whole genomes

  Nature · 2020 · https://doi.org/10.1038/s41586-020-1965-x

• The GTEx Consortium atlas of genetic regulatory effects across human tissues

  Science · 2020 · https://doi.org/10.1126/science.aaz1776

• Single-cell transcriptomic analysis of Alzheimer’s disease

  Nature · 2019 · 10.1038/s41586-019-1195-2

• Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use

  Nature Genetics · 2019 · 10.1038/s41588-018-0307-5

• GENCODE reference annotation for the human and mouse genomes

  Nucleic Acids Research · 2018 · https://doi.org/10.1093/nar/gky955

• FTO Obesity Variant Circuitry and Adipocyte Browning in Humans

  New England Journal of Medicine · 2015 · 10.1056/nejmoa1502214

• A comparative encyclopedia of DNA elements in the mouse genome

  Nature · 2014 · 10.1038/nature13992

• ChIP-seq guidelines and practices of the ENCODE and modENCODE consortia

  Genome Research · 2012 · 10.1101/gr.136184.111

• GENCODE: The reference human genome annotation for The ENCODE Project

  Genome Research · 2012 · https://doi.org/10.1101/gr.135350.111

• Wisdom of crowds for robust gene network inference

  Nature Methods · 2012 · 10.1038/nmeth.2016

• An integrated encyclopedia of DNA elements in the human genome

  The Journal of the American Medical Association (JAMA) Network (American Medical Association) · 2012

• Mapping and analysis of chromatin state dynamics in nine human cell types

  Nature · 2011 · https://doi.org/10.1038/nature09906

• Discovery and characterization of chromatin states for systematic annotation of the human genome

  Nature Biotechnology · 2010 · 10.1038/nbt.1662

• The NIH Roadmap Epigenomics Mapping Consortium

  Nature Biotechnology · 2010 · 10.1038/nbt1010-1045

• Identification of Functional Elements and Regulatory Circuits by Drosophila modENCODE

  Science · 2010 · 10.1126/science.1198374

• Comprehensive analysis of the chromatin landscape in Drosophila melanogaster

  Nature · 2010 · 10.1038/nature09725

• Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals

  Nature · 2009 · https://doi.org/10.1038/nature07672

• Histone modifications at human enhancers reflect global cell-type-specific gene expression

  Nature · 2009 · 10.1038/nature07829

• Evolution of pathogenicity and sexual reproduction in eight Candida genomes

  Nature · 2009 · 10.1038/nature08064

• Discrete Small RNA-Generating Loci as Master Regulators of Transposon Activity in Drosophila

  Cell · 2007 · 10.1016/j.cell.2007.01.043

• Genome sequence, comparative analysis and haplotype structure of the domestic dog

  Nature · 2005 · 10.1038/nature04338

• Systematic discovery of regulatory motifs in human promoters and 3′ UTRs by comparison of several mammals

  Nature · 2005 · 10.1038/nature03441

• Transcriptional regulatory code of a eukaryotic genome

  Nature · 2004 · 10.1038/nature02800

• Genome duplication in the teleost fish Tetraodon nigroviridis reveals the early vertebrate proto-karyotype

  Nature · 2004 · 10.1038/nature03025

• Proof and evolutionary analysis of ancient genome duplication in the yeast Saccharomyces cerevisiae

  Nature · 2004 · 10.1038/nature02424

• Sequencing and comparison of yeast species to identify genes and regulatory elements

  Nature · 2003 · 10.1038/nature01644

Current projects

No projects listed.