John A. Kellum

Research interests

Publications

• Redefining critical illness

  Nature Medicine · 2022 · https://doi.org/10.1038/s41591-022-01843-x

• Mitochondria ROS and mitophagy in acute kidney injury

  Autophagy · 2022 · 10.1080/15548627.2022.2084862

• Postoperative acute kidney injury in adult non-cardiac surgery: joint consensus report of the Acute Disease Quality Initiative and PeriOperative Quality Initiative

  Nature Reviews Nephrology · 2021 · https://doi.org/10.1038/s41581-021-00418-2

• Effect of Intravenous Fluid Treatment With a Balanced Solution vs 0.9% Saline Solution on Mortality in Critically Ill Patients

  JAMA · 2021 · https://doi.org/10.1001/jama.2021.11684

• Controversies in acute kidney injury: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Conference

  Kidney International · 2020 · https://doi.org/10.1016/j.kint.2020.04.020

• COVID-19-associated acute kidney injury: consensus report of the 25th Acute Disease Quality Initiative (ADQI) Workgroup

  Nature Reviews Nephrology · 2020 · https://doi.org/10.1038/s41581-020-00356-5

• Recommendations on Acute Kidney Injury Biomarkers From the Acute Disease Quality Initiative Consensus Conference

  JAMA Network Open · 2020 · https://doi.org/10.1001/jamanetworkopen.2020.19209

• Intravenous fluid resuscitation is associated with septic endothelial glycocalyx degradation

  Critical Care · 2019 · https://doi.org/10.1186/s13054-019-2534-2

• Association of Net Ultrafiltration Rate With Mortality Among Critically Ill Adults With Acute Kidney Injury Receiving Continuous Venovenous Hemodiafiltration

  JAMA Network Open · 2019 · https://doi.org/10.1001/jamanetworkopen.2019.5418

• Lung–kidney interactions in critically ill patients: consensus report of the Acute Disease Quality Initiative (ADQI) 21 Workgroup

  Intensive Care Medicine · 2019 · https://doi.org/10.1007/s00134-019-05869-7

• Acute kidney injury

  The Lancet · 2019 · https://doi.org/10.1016/s0140-6736(19)32563-2

• Derivation, Validation, and Potential Treatment Implications of Novel Clinical Phenotypes for Sepsis

  JAMA · 2019 · https://doi.org/10.1001/jama.2019.5791

• Long-term Host Immune Response Trajectories Among Hospitalized Patients With Sepsis

  JAMA Network Open · 2019 · https://doi.org/10.1001/jamanetworkopen.2019.8686

• Acute kidney injury from sepsis: current concepts, epidemiology, pathophysiology, prevention and treatment

  Kidney International · 2019 · 10.1016/j.kint.2019.05.026

• Global epidemiology and outcomes of acute kidney injury

  Nature Reviews Nephrology · 2018 · 10.1038/s41581-018-0052-0

• Acute kidney disease and renal recovery: consensus report of the Acute Disease Quality Initiative (ADQI) 16 Workgroup

  Nature Reviews Nephrology · 2017 · 10.1038/nrneph.2017.2

• Acute kidney injury in sepsis

  Intensive Care Medicine · 2017 · 10.1007/s00134-017-4755-7

• PEBP1 Wardens Ferroptosis by Enabling Lipoxygenase Generation of Lipid Death Signals

  Cell · 2017 · 10.1016/j.cell.2017.09.044

• Cellular and Molecular Mechanisms of AKI

  Journal of the American Society of Nephrology · 2016 · https://doi.org/10.1681/asn.2015070740

• The Endothelium in Sepsis

  Shock · 2016 · https://doi.org/10.1097/shk.0000000000000473

• Effect of Early vs Delayed Initiation of Renal Replacement Therapy on Mortality in Critically Ill Patients With Acute Kidney Injury

  JAMA · 2016 · 10.1001/jama.2016.5828

• Classifying AKI by Urine Output versus Serum Creatinine Level

  Journal of the American Society of Nephrology · 2015 · https://doi.org/10.1681/asn.2014070724

• Epidemiology of acute kidney injury in critically ill patients: the multinational AKI-EPI study

  Intensive Care Medicine · 2015 · 10.1007/s00134-015-3934-7

• Immune Cell Phenotype and Function in Sepsis

  Shock · 2015 · https://doi.org/10.1097/shk.0000000000000495

• Four phases of intravenous fluid therapy: a conceptual model

  British Journal of Anaesthesia · 2014 · https://doi.org/10.1093/bja/aeu300

• Acute kidney injury: an increasing global concern

  The Lancet · 2013 · 10.1016/s0140-6736(13)60647-9

• A Unified Theory of Sepsis-Induced Acute Kidney Injury

  Shock · 2013 · 10.1097/shk.0000000000000052

• Discovery and validation of cell cycle arrest biomarkers in human acute kidney injury

  Critical Care · 2013 · 10.1186/cc12503

• Diagnosis, evaluation, and management of acute kidney injury: a KDIGO summary (Part 1)

  Critical Care · 2013 · 10.1186/cc11454

• Potential use of biomarkers in acute kidney injury: report and summary of recommendations from the 10th Acute Dialysis Quality Initiative consensus conference

  Kidney International · 2013 · https://doi.org/10.1038/ki.2013.374

• Major Complications, Mortality, and Resource Utilization After Open Abdominal Surgery

  Annals of Surgery · 2012 · 10.1097/sla.0b013e31825074f5

• A comparison of three methods to estimate baseline creatinine for RIFLE classification

  Nephrology Dialysis Transplantation · 2010 · https://doi.org/10.1093/ndt/gfp766

• Understanding the Inflammatory Cytokine Response in Pneumonia and Sepsis

  Archives of Internal Medicine · 2007 · 10.1001/archinte.167.15.1655

• Septic Acute Kidney Injury in Critically Ill Patients

  Clinical Journal of the American Society of Nephrology · 2007 · 10.2215/cjn.03681106

• Acute Kidney Injury Network: report of an initiative to improve outcomes in acute kidney injury

  Critical Care · 2007 · 10.1186/cc5713

• Findings of the First Consensus Conference on Medical Emergency Teams*

  Critical Care Medicine · 2006 · 10.1097/01.ccm.0000235743.38172.6e

• RIFLE criteria for acute kidney injury are associated with hospital mortality in critically ill patients: a cohort analysis

  Critical Care · 2006 · 10.1186/cc4915

• Acute renal failure – definition, outcome measures, animal models, fluid therapy and information technology needs: the Second International Consensus Conference of the Acute Dialysis Quality Initiative (ADQI) Group

  Critical Care · 2004 · 10.1186/cc2872

Current projects

No projects listed.