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Mark W. Dewhirst

Researcher Next ID · RN-025978

Researcher · Biochemistry, Genetics and Molecular Biology

Duke University

Durham, Chile

Not currently recruitingFunding unknown
Works count
1,020
Citation count
61,815
H-index
120
i10-index
504

Research interests

Biochemistry, Genetics and Molecular Biology
Engineering
Medicine
Cancer, Hypoxia, and Metabolism
Ultrasound and Hyperthermia Applications
Nanoplatforms for cancer theranostics
Angiogenesis and VEGF in Cancer
Medical Imaging Techniques and Applications

Publications

  • A dual-emissive-materials design concept enables tumour hypoxia imaging

    Nature Materials · 2009 · https://doi.org/10.1038/nmat2509

  • Targeting lactate-fueled respiration selectively kills hypoxic tumor cells in mice

    Journal of Clinical Investigation · 2008 · https://doi.org/10.1172/jci36843

  • Tumor Angiogenic and Hypoxic Profiles Predict Radiographic Response and Survival in Malignant Astrocytoma Patients Treated With Bevacizumab and Irinotecan

    Journal of Clinical Oncology · 2008 · https://doi.org/10.1200/jco.2007.13.3652

  • Glioma stem cells promote radioresistance by preferential activation of the DNA damage response

    Nature · 2006 · https://doi.org/10.1038/nature05236

  • Basic principles of thermal dosimetry and thermal thresholds for tissue damage from hyperthermia

    International Journal of Hyperthermia · 2003 · https://doi.org/10.1080/0265673031000119006

  • Mechanisms associated with tumor vascular shut-down induced by combretastatin A-4 phosphate: intravital microscopy and measurement of vascular permeability.

    PubMed · 2001

  • Tumor hypoxia adversely affects the prognosis of carcinoma of the head and neck

    International Journal of Radiation Oncology*Biology*Physics · 1997 · https://doi.org/10.1016/s0360-3016(97)00101-6

Current projects

    No projects listed.