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Mindaugas Valius

Researcher Next ID · RN-026081

Researcher · Biochemistry, Genetics and Molecular Biology

Vilnius University

Vilnius, Lithuania

Not currently recruitingFunding unknown
Works count
108
Citation count
3,614
H-index
28
i10-index
47

Research interests

Biochemistry, Genetics and Molecular Biology
Environmental Science
Protein Kinase Regulation and GTPase Signaling
PI3K/AKT/mTOR signaling in cancer
Bacteriophages and microbial interactions
Microtubule and mitosis dynamics
Genomics and Phylogenetic Studies

Publications

  • KRAS, NRAS and BRAF mutations in colorectal cancer and melanoma

    Medical Oncology · 2017 · 10.1007/s12032-016-0879-9

  • Roscovitine in cancer and other diseases.

    PubMed · 2015 · https://doi.org/10.3978/j.issn.2305-5839.2015.03.61

  • Highlights of the Latest Advances in Research on CDK Inhibitors

    Cancers · 2014 · 10.3390/cancers6042224

  • The CDK inhibitors in cancer research and therapy

    Journal of Cancer Research and Clinical Oncology · 2011 · https://doi.org/10.1007/s00432-011-1039-4

  • Platelet-Derived Growth Factor-Dependent Activation of Phosphatidylinositol 3-Kinase Is Regulated by Receptor Binding of SH2-Domain-Containing Proteins Which Influence Ras Activity

    Molecular and Cellular Biology · 1996 · 10.1128/mcb.16.10.5905

  • Mitogen-Activated Protein Kinase Activation Is Insufficient for Growth Factor Receptor-Mediated PC12 Cell Differentiation

    Molecular and Cellular Biology · 1995 · 10.1128/mcb.15.7.3644

  • Tyrosines 1021 and 1009 are phosphorylation sites in the carboxy terminus of the platelet-derived growth factor receptor beta subunit and are required for binding of phospholipase C gamma and a 64-kilodalton protein, respectively.

    Molecular and Cellular Biology · 1993 · 10.1128/mcb.13.1.133

  • The 64-kDa protein that associates with the platelet-derived growth factor receptor beta subunit via Tyr-1009 is the SH2-containing phosphotyrosine phosphatase Syp.

    Proceedings of the National Academy of Sciences · 1993 · https://doi.org/10.1073/pnas.90.15.6939

  • Phospholipase C-γ1 and phosphatidylinositol 3 kinase are the downstream mediators of the PDGF receptor's mitogenic signal

    Cell · 1993 · https://doi.org/10.1016/0092-8674(93)90232-f

  • GTPase-activating protein and phosphatidylinositol 3-kinase bind to distinct regions of the platelet-derived growth factor receptor beta subunit.

    Molecular and Cellular Biology · 1992 · https://doi.org/10.1128/mcb.12.6.2534

Current projects

    No projects listed.