Martin Hrabě de Angelis

Research interests

Publications

• Pathophysiology-based subphenotyping of individuals at elevated risk for type 2 diabetes

  Nature Medicine · 2021 · 10.1038/s41591-020-1116-9

• Animal models of obesity and diabetes mellitus

  Nature Reviews Endocrinology · 2018 · 10.1038/nrendo.2017.161

• Towards frailty biomarkers: Candidates from genes and pathways regulated in aging and age-related diseases

  Ageing Research Reviews · 2018 · 10.1016/j.arr.2018.07.004

• Cardioprotection and lifespan extension by the natural polyamine spermidine

  Nature Medicine · 2016 · https://doi.org/10.1038/nm.4222

• High-throughput discovery of novel developmental phenotypes

  Nature · 2016 · https://doi.org/10.1038/nature19356

• Epigenetic germline inheritance of diet-induced obesity and insulin resistance

  Nature Genetics · 2016 · 10.1038/ng.3527

• Aberrant methylation of tRNAs links cellular stress to neuro‐developmental disorders

  The EMBO Journal · 2014 · https://doi.org/10.15252/embj.201489282

• Rapamycin extends murine lifespan but has limited effects on aging

  Journal of Clinical Investigation · 2013 · 10.1172/jci67674

• A comparative phenotypic and genomic analysis of C57BL/6J and C57BL/6N mouse strains

  Genome biology · 2013 · 10.1186/gb-2013-14-7-r82

• Identification of Serum Metabolites Associated With Risk of Type 2 Diabetes Using a Targeted Metabolomic Approach

  Diabetes · 2012 · https://doi.org/10.2337/db12-0495

• Novel biomarkers for pre‐diabetes identified by metabolomics

  Molecular Systems Biology · 2012 · https://doi.org/10.1038/msb.2012.43

• Human metabolic individuality in biomedical and pharmaceutical research

  Nature · 2011 · 10.1038/nature10354

• Cyclooxygenase-2 Controls Energy Homeostasis in Mice by de Novo Recruitment of Brown Adipocytes

  Science · 2010 · 10.1126/science.1186034

• Post-Stroke Inhibition of Induced NADPH Oxidase Type 4 Prevents Oxidative Stress and Neurodegeneration

  PLoS Biology · 2010 · 10.1371/journal.pbio.1000479

• Metabolic Footprint of Diabetes: A Multiplatform Metabolomics Study in an Epidemiological Setting

  PLoS ONE · 2010 · 10.1371/journal.pone.0013953

• A genome-wide perspective of genetic variation in human metabolism

  Nature Genetics · 2009 · 10.1038/ng.507

• A Humanized Version of Foxp2 Affects Cortico-Basal Ganglia Circuits in Mice

  Cell · 2009 · 10.1016/j.cell.2009.03.041

• Ribosomal mutations cause p53-mediated dark skin and pleiotropic effects

  Nature Genetics · 2008 · 10.1038/ng.188

• Genetics Meets Metabolomics: A Genome-Wide Association Study of Metabolite Profiles in Human Serum

  PLoS Genetics · 2008 · 10.1371/journal.pgen.1000282

• Cytoplasmic Thioredoxin Reductase Is Essential for Embryogenesis but Dispensable for Cardiac Development

  Molecular and Cellular Biology · 2005 · 10.1128/mcb.25.5.1980-1988.2005

• Mutations in Dynein Link Motor Neuron Degeneration to Defects in Retrograde Transport

  Science · 2003 · 10.1126/science.1083129

• Genome-wide, large-scale production of mutant mice by ENU mutagenesis

  Nature Genetics · 2000 · 10.1038/78146

• Notch signalling controls pancreatic cell differentiation

  Nature · 1999 · 10.1038/23716

• Maintenance of somite borders in mice requires the Delta homologue Dll1

  Nature · 1997 · 10.1038/386717a0

• Transient and restricted expression during mouse embryogenesis of Dll1, a murine gene closely related to Drosophila Delta

  Development · 1995 · 10.1242/dev.121.8.2407

Current projects

No projects listed.