Kai Kaarniranta

Research interests

Publications

• FinnGen provides genetic insights from a well-phenotyped isolated population

  Nature · 2023 · https://doi.org/10.1038/s41586-022-05473-8

• FinnGen: Unique genetic insights from combining isolated population and national health register data

  medRxiv · 2022 · 10.1101/2022.03.03.22271360

• Photoaging: UV radiation-induced inflammation and immunosuppression accelerate the aging process in the skin

  Inflammation Research · 2022 · 10.1007/s00011-022-01598-8

• Mechanisms of mitochondrial dysfunction and their impact on age-related macular degeneration

  Progress in Retinal and Eye Research · 2020 · 10.1016/j.preteyeres.2020.100858

• Inflammation and its role in age-related macular degeneration

  Cellular and Molecular Life Sciences · 2016 · 10.1007/s00018-016-2147-8

• Polyphenol Stilbenes: Molecular Mechanisms of Defence against Oxidative Stress and Aging-Related Diseases

  Oxidative Medicine and Cellular Longevity · 2015 · 10.1155/2015/340520

• Oxidative Stress, Hypoxia, and Autophagy in the Neovascular Processes of Age-Related Macular Degeneration

  BioMed Research International · 2014 · 10.1155/2014/768026

• Antagonistic crosstalk between NF-κB and SIRT1 in the regulation of inflammation and metabolic disorders

  Cellular Signalling · 2013 · https://doi.org/10.1016/j.cellsig.2013.06.007

• Crosstalk between Oxidative Stress and SIRT1: Impact on the Aging Process

  International Journal of Molecular Sciences · 2013 · 10.3390/ijms14023834

• Impaired autophagy and APP processing in Alzheimer's disease: The potential role of Beclin 1 interactome

  Progress in Neurobiology · 2013 · 10.1016/j.pneurobio.2013.06.002

• Autophagy and heterophagy dysregulation leads to retinal pigment epithelium dysfunction and development of age-related macular degeneration

  Autophagy · 2013 · 10.4161/auto.24546

• Maturation of autophagosomes and endosomes: A key role for Rab7

  Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · 2012 · 10.1016/j.bbamcr.2012.11.018

• Mitochondrial dysfunction and oxidative stress activate inflammasomes: impact on the aging process and age-related diseases

  Cellular and Molecular Life Sciences · 2012 · 10.1007/s00018-012-0962-0

• Inflammaging: disturbed interplay between autophagy and inflammasomes

  Aging · 2012 · 10.18632/aging.100444

• Astrocytes in the aging brain express characteristics of senescence-associated secretory phenotype

  European Journal of Neuroscience · 2011 · 10.1111/j.1460-9568.2011.07738.x

• Age-Related Macular Degeneration (AMD): Alzheimer's Disease in the Eye?

  Journal of Alzheimer s Disease · 2011 · 10.3233/jad-2011-101908

• Emerging role of NF-κB signaling in the induction of senescence-associated secretory phenotype (SASP)

  Cellular Signalling · 2011 · https://doi.org/10.1016/j.cellsig.2011.12.006

• AMP-activated protein kinase inhibits NF-κB signaling and inflammation: impact on healthspan and lifespan

  Journal of Molecular Medicine · 2011 · https://doi.org/10.1007/s00109-011-0748-0

• AMP-activated protein kinase (AMPK) controls the aging process via an integrated signaling network

  Ageing Research Reviews · 2011 · https://doi.org/10.1016/j.arr.2011.12.005

• Celastrol: Molecular targets of Thunder God Vine

  Biochemical and Biophysical Research Communications · 2010 · 10.1016/j.bbrc.2010.03.050

• ER stress in Alzheimer's disease: a novel neuronal trigger for inflammation and Alzheimer's pathology

  Journal of Neuroinflammation · 2009 · 10.1186/1742-2094-6-41

• Inflammation in Alzheimer's disease: Amyloid-β oligomers trigger innate immunity defence via pattern recognition receptors

  Progress in Neurobiology · 2009 · 10.1016/j.pneurobio.2009.01.001

• Regulation of the aging process by autophagy

  Trends in Molecular Medicine · 2009 · 10.1016/j.molmed.2009.03.004

• Terpenoids: natural inhibitors of NF-κB signaling with anti-inflammatory and anticancer potential

  Cellular and Molecular Life Sciences · 2008 · 10.1007/s00018-008-8103-5

• Activation of innate immunity system during aging: NF-kB signaling is the molecular culprit of inflamm-aging

  Ageing Research Reviews · 2007 · 10.1016/j.arr.2007.09.002

Current projects

No projects listed.