Chim C. Lang

Research interests

Publications

• Semaglutide and cardiovascular outcomes in patients with obesity and prevalent heart failure: a prespecified analysis of the SELECT trial

  The Lancet · 2024 · https://doi.org/10.1016/s0140-6736(24)01498-3

• Cardiovascular outcomes in adults with hypertension with evening versus morning dosing of usual antihypertensives in the UK (TIME study): a prospective, randomised, open-label, blinded-endpoint clinical trial

  The Lancet · 2022 · https://doi.org/10.1016/s0140-6736(22)01786-x

• Intravenous ferric derisomaltose in patients with heart failure and iron deficiency in the UK (IRONMAN): an investigator-initiated, prospective, randomised, open-label, blinded-endpoint trial

  The Lancet · 2022 · https://doi.org/10.1016/s0140-6736(22)02083-9

• A randomized controlled trial of dapagliflozin on left ventricular hypertrophy in people with type two diabetes: the DAPA-LVH trial

  European Heart Journal · 2020 · https://doi.org/10.1093/eurheartj/ehaa419

• Renal and Cardiovascular Effects of SGLT2 Inhibition in Combination With Loop Diuretics in Patients With Type 2 Diabetes and Chronic Heart Failure

  Circulation · 2020 · https://doi.org/10.1161/circulationaha.120.048739

• Circulating plasma concentrations of angiotensin-converting enzyme 2 in men and women with heart failure and effects of renin–angiotensin–aldosterone inhibitors

  European Heart Journal · 2020 · https://doi.org/10.1093/eurheartj/ehaa373

• Identifying optimal doses of heart failure medications in men compared with women: a prospective, observational, cohort study

  The Lancet · 2019 · https://doi.org/10.1016/s0140-6736(19)31792-1

• Cardiovascular Effects of Switching From Tobacco Cigarettes to Electronic Cigarettes

  Journal of the American College of Cardiology · 2019 · https://doi.org/10.1016/j.jacc.2019.09.067

• The Clinical Significance of Interleukin-6 in Heart Failure: Results from the BIOSTAT-CHF Study

  European Journal of Heart Failure · 2019 · https://doi.org/10.1002/ejhf.1482

• Identifying Pathophysiological Mechanisms in Heart Failure With Reduced Versus Preserved Ejection Fraction

  Journal of the American College of Cardiology · 2018 · https://doi.org/10.1016/j.jacc.2018.06.050

• Determinants and clinical outcome of uptitration of ACE-inhibitors and beta-blockers in patients with heart failure: a prospective European study

  European Heart Journal · 2017 · https://doi.org/10.1093/eurheartj/ehx026

• Development and Validation of Multivariable Models to Predict Mortality and Hospitalization in Patients with Heart Failure

  European Journal of Heart Failure · 2017 · https://doi.org/10.1002/ejhf.785

• Anti-Inflammatory Effects of Metformin Irrespective of Diabetes Status

  Circulation Research · 2016 · https://doi.org/10.1161/circresaha.116.308445

• High-sensitivity troponin I concentrations are a marker of an advanced hypertrophic response and adverse outcomes in patients with aortic stenosis

  European Heart Journal · 2014 · https://doi.org/10.1093/eurheartj/ehu189

• The effects of the cardiac myosin activator, omecamtiv mecarbil, on cardiac function in systolic heart failure: a double-blind, placebo-controlled, crossover, dose-ranging phase 2 trial

  The Lancet · 2011 · https://doi.org/10.1016/s0140-6736(11)61126-4

• Allopurinol Benefits Left Ventricular Mass and Endothelial Dysfunction in Chronic Kidney Disease

  Journal of the American Society of Nephrology · 2011 · https://doi.org/10.1681/asn.2010111185

• Effect of high-dose allopurinol on exercise in patients with chronic stable angina: a randomised, placebo controlled crossover trial

  The Lancet · 2010 · https://doi.org/10.1016/s0140-6736(10)60391-1

• Diastolic Dysfunction in Heart Failure With Preserved Systolic Function: Need for Objective Evidence

  Journal of the American College of Cardiology · 2007 · https://doi.org/10.1016/j.jacc.2006.08.062

• Clinical Correlates and Consequences of Anemia in a Broad Spectrum of Patients With Heart Failure

  Circulation · 2006 · https://doi.org/10.1161/circulationaha.105.582577

• Obesity and the risk of myocardial infarction in 27 000 participants from 52 countries: a case-control study

  The Lancet · 2005 · https://doi.org/10.1016/s0140-6736(05)67663-5

• Effect of Erythropoietin on Exercise Capacity in Patients With Moderate to Severe Chronic Heart Failure

  Circulation · 2003 · https://doi.org/10.1161/01.cir.0000044914.42696.6a

• Effects of adding spironolactone to an angiotensin-converting enzyme inhibitor in chronic congestive heart failure secondary to coronary artery disease

  The American Journal of Cardiology · 1995 · https://doi.org/10.1016/s0002-9149(99)80353-1

• QT dispersion and sudden unexpected death in chronic heart failure

  The Lancet · 1994 · https://doi.org/10.1016/s0140-6736(94)91164-9

• The effect of intravenous saline loading on plasma levels of brain natriuretic peptide in man

  Journal of Hypertension · 1993 · https://doi.org/10.1097/00004872-199307000-00009

Current projects

No projects listed.