Bing Ren

Research interests

Publications

• A multimodal cell census and atlas of the mammalian primary motor cortex

  Nature · 2021 · https://doi.org/10.1038/s41586-021-03950-0

• Comparative cellular analysis of motor cortex in human, marmoset and mouse

  Nature · 2021 · https://doi.org/10.1038/s41586-021-03465-8

• Metabolic regulation of gene expression by histone lactylation

  Nature · 2019 · https://doi.org/10.1038/s41586-019-1678-1

• Brain cell type–specific enhancer–promoter interactome maps and disease - risk association

  Science · 2019 · https://doi.org/10.1126/science.aay0793

• Multi-platform discovery of haplotype-resolved structural variation in human genomes

  Nature Communications · 2019 · https://doi.org/10.1038/s41467-018-08148-z

• Extrachromosomal oncogene amplification drives tumour evolution and genetic heterogeneity

  Nature · 2017 · 10.1038/nature21356

• A Compendium of Chromatin Contact Maps Reveals Spatially Active Regions in the Human Genome

  Cell Reports · 2016 · 10.1016/j.celrep.2016.10.061

• Chromatin architecture reorganization during stem cell differentiation

  Nature · 2015 · 10.1038/nature14222

• CRISPR Inversion of CTCF Sites Alters Genome Topology and Enhancer/Promoter Function

  Cell · 2015 · 10.1016/j.cell.2015.07.038

• Integrative analysis of 111 reference human epigenomes

  Nature · 2015 · https://doi.org/10.1038/nature14248

• Defining functional DNA elements in the human genome

  Proceedings of the National Academy of Sciences · 2014 · 10.1073/pnas.1318948111

• Topologically associating domains are stable units of replication-timing regulation

  Nature · 2014 · 10.1038/nature13986

• N6-methyladenosine-dependent regulation of messenger RNA stability

  Nature · 2013 · https://doi.org/10.1038/nature12730

• A high-resolution map of the three-dimensional chromatin interactome in human cells

  Nature · 2013 · 10.1038/nature12644

• Topological domains in mammalian genomes identified by analysis of chromatin interactions

  Nature · 2012 · https://doi.org/10.1038/nature11082

• Base-Resolution Analysis of 5-Hydroxymethylcytosine in the Mammalian Genome

  Cell · 2012 · 10.1016/j.cell.2012.04.027

• A map of the cis-regulatory sequences in the mouse genome

  Nature · 2012 · 10.1038/nature11243

• Identification of 67 Histone Marks and Histone Lysine Crotonylation as a New Type of Histone Modification

  Cell · 2011 · 10.1016/j.cell.2011.08.008

• Hotspots of aberrant epigenomic reprogramming in human induced pluripotent stem cells

  Nature · 2011 · 10.1038/nature09798

• The NIH Roadmap Epigenomics Mapping Consortium

  Nature Biotechnology · 2010 · 10.1038/nbt1010-1045

• Identification of Functional Elements and Regulatory Circuits by Drosophila modENCODE

  Science · 2010 · 10.1126/science.1198374

• Human DNA methylomes at base resolution show widespread epigenomic differences

  Nature · 2009 · https://doi.org/10.1038/nature08514

• Histone modifications at human enhancers reflect global cell-type-specific gene expression

  Nature · 2009 · 10.1038/nature07829

• Analysis of the Vertebrate Insulator Protein CTCF-Binding Sites in the Human Genome

  Cell · 2007 · 10.1016/j.cell.2006.12.048

• Distinct and predictive chromatin signatures of transcriptional promoters and enhancers in the human genome

  Nature Genetics · 2007 · 10.1038/ng1966

• A high-resolution map of active promoters in the human genome

  Nature · 2005 · 10.1038/nature03877

• Transcriptional Regulatory Networks in Saccharomyces cerevisiae

  Science · 2002 · 10.1126/science.1075090

• Remodeling of Yeast Genome Expression in Response to Environmental Changes

  Molecular Biology of the Cell · 2001 · 10.1091/mbc.12.2.323

• Genome-Wide Location and Function of DNA Binding Proteins

  Science · 2000 · 10.1126/science.290.5500.2306

Current projects

No projects listed.