Ye Fu

Research interests

Publications

• ALKBH1-Mediated tRNA Demethylation Regulates Translation

  Cell · 2016 · https://doi.org/10.1016/j.cell.2016.09.038

• Abundant DNA 6mA methylation during early embryogenesis of zebrafish and pig

  Nature Communications · 2016 · https://doi.org/10.1038/ncomms13052

• N6-Methyldeoxyadenosine Marks Active Transcription Start Sites in Chlamydomonas

  Cell · 2015 · https://doi.org/10.1016/j.cell.2015.04.010

• Gene expression regulation mediated through reversible m6A RNA methylation

  Nature Reviews Genetics · 2014 · https://doi.org/10.1038/nrg3724

• High‐Resolution N6‐Methyladenosine (m6A) Map Using Photo‐Crosslinking‐Assisted m6A Sequencing

  Angewandte Chemie International Edition · 2014 · https://doi.org/10.1002/anie.201410647

• Nucleic Acid Oxidation in DNA Damage Repair and Epigenetics

  Chemical Reviews · 2014 · https://doi.org/10.1021/cr400432d

• Crystal structure of the RNA demethylase ALKBH5 from zebrafish

  FEBS Letters · 2014 · https://doi.org/10.1016/j.febslet.2014.02.021

• A TET Homologue Protein from Coprinopsis cinerea (CcTET) That Biochemically Converts 5-Methylcytosine to 5-Hydroxymethylcytosine, 5-Formylcytosine, and 5-Carboxylcytosine

  Journal of the American Chemical Society · 2014 · https://doi.org/10.1021/ja500979k

• Sprouts of RNA epigenetics

  RNA Biology · 2013 · https://doi.org/10.4161/rna.24711

• A METTL3–METTL14 complex mediates mammalian nuclear RNA N6-adenosine methylation

  Nature Chemical Biology · 2013 · https://doi.org/10.1038/nchembio.1432

• Genome-wide Profiling of 5-Formylcytosine Reveals Its Roles in Epigenetic Priming

  Cell · 2013 · https://doi.org/10.1016/j.cell.2013.04.001

• FTO-mediated formation of N6-hydroxymethyladenosine and N6-formyladenosine in mammalian RNA

  Nature Communications · 2013 · https://doi.org/10.1038/ncomms2822

• ALKBH4-dependent demethylation of actin regulates actomyosin dynamics

  Nature Communications · 2013 · https://doi.org/10.1038/ncomms2863

• N6-methyladenosine-dependent regulation of messenger RNA stability

  Nature · 2013 · https://doi.org/10.1038/nature12730

• Proteome-wide Quantification and Characterization of Oxidation-Sensitive Cysteines in Pathogenic Bacteria

  Cell Host & Microbe · 2013 · https://doi.org/10.1016/j.chom.2013.02.004

• Reversible RNA adenosine methylation in biological regulation

  Trends in Genetics · 2012 · https://doi.org/10.1016/j.tig.2012.11.003

• Nucleic acid modifications with epigenetic significance

  Current Opinion in Chemical Biology · 2012 · https://doi.org/10.1016/j.cbpa.2012.10.002

• ALKBH5 Is a Mammalian RNA Demethylase that Impacts RNA Metabolism and Mouse Fertility

  Molecular Cell · 2012 · https://doi.org/10.1016/j.molcel.2012.10.015

• A genetically incorporated crosslinker reveals chaperone cooperation in acid resistance

  Nature Chemical Biology · 2011 · https://doi.org/10.1038/nchembio.644

• N6-Methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTO

  Nature Chemical Biology · 2011 · https://doi.org/10.1038/nchembio.687

• The AlkB Domain of Mammalian ABH8 Catalyzes Hydroxylation of 5‐Methoxycarbonylmethyluridine at the Wobble Position of tRNA

  Angewandte Chemie International Edition · 2010 · https://doi.org/10.1002/anie.201001242

• Selective chemical labeling reveals the genome-wide distribution of 5-hydroxymethylcytosine

  Nature Biotechnology · 2010 · 10.1038/nbt.1732

• Genome-wide analysis of N 1 -methyl-adenosine modification in human tRNAs

  RNA · 2010 · https://doi.org/10.1261/rna.2057810

• Expedient Syntheses of Antofine and Cryptopleurine via Intramolecular 1,3-Dipolar Cycloaddition

  The Journal of Organic Chemistry · 2007 · https://doi.org/10.1021/jo070668x

• Synthesis and structure–activity studies of antofine analogues as potential anticancer agents

  Bioorganic & Medicinal Chemistry Letters · 2006 · https://doi.org/10.1016/j.bmcl.2006.09.080

Current projects

No projects listed.