A.S. Verkman

Research interests

Publications

• Diabetes insipidus

  Nature Reviews Disease Primers · 2019 · https://doi.org/10.1038/s41572-019-0103-2

• Aquaporins: important but elusive drug targets

  Nature Reviews Drug Discovery · 2014 · https://doi.org/10.1038/nrd4226

• Aquaporin water channels in the nervous system

  Nature reviews. Neuroscience · 2013 · https://doi.org/10.1038/nrn3468

• Aquaporin-4 and brain edema

  Pediatric Nephrology · 2007 · https://doi.org/10.1007/s00467-006-0411-0

• Aquaporins and cell migration

  Pflügers Archiv - European Journal of Physiology · 2007 · https://doi.org/10.1007/s00424-007-0357-5

• Impairment of angiogenesis and cell migration by targeted aquaporin-1 gene disruption

  Nature · 2005 · https://doi.org/10.1038/nature03460

• More than just water channels: unexpected cellular roles of aquaporins

  Journal of Cell Science · 2005 · https://doi.org/10.1242/jcs.02519

• Aquaporin‐4 facilitates reabsorption of excess fluid in vasogenic brain edema

  The FASEB Journal · 2004 · https://doi.org/10.1096/fj.04-1723fje

• Reduced cerebrospinal fluid production and intracranial pressure in mice lacking choroid plexus water channel Aquaporin‐1

  The FASEB Journal · 2004 · https://doi.org/10.1096/fj.04-1711fje

• Chloride Accumulation and Swelling in Endosomes Enhances DNA Transfer by Polyamine-DNA Polyplexes

  Journal of Biological Chemistry · 2003 · https://doi.org/10.1074/jbc.m308643200

• Solute and macromolecule diffusion in cellular aqueous compartments

  Trends in Biochemical Sciences · 2002 · https://doi.org/10.1016/s0968-0004(01)02003-5

• Structure and function of aquaporin water channels

  American Journal of Physiology-Renal Physiology · 2000 · https://doi.org/10.1152/ajprenal.2000.278.1.f13

• Aquaporin-4 deletion in mice reduces brain edema after acute water intoxication and ischemic stroke

  Nature Medicine · 2000 · https://doi.org/10.1038/72256

• Size-dependent DNA Mobility in Cytoplasm and Nucleus

  Journal of Biological Chemistry · 2000 · https://doi.org/10.1074/jbc.275.3.1625

• Defective Secretion of Saliva in Transgenic Mice Lacking Aquaporin-5 Water Channels

  Journal of Biological Chemistry · 1999 · https://doi.org/10.1074/jbc.274.29.20071

• Severely Impaired Urinary Concentrating Ability in Transgenic Mice Lacking Aquaporin-1 Water Channels

  Journal of Biological Chemistry · 1998 · https://doi.org/10.1074/jbc.273.8.4296

• Photobleaching recovery and anisotropy decay of green fluorescent protein GFP-S65T in solution and cells: cytoplasmic viscosity probed by green fluorescent protein translational and rotational diffusion

  Biophysical Journal · 1997 · https://doi.org/10.1016/s0006-3495(97)78835-0

• Generation and phenotype of a transgenic knockout mouse lacking the mercurial-insensitive water channel aquaporin-4.

  Journal of Clinical Investigation · 1997 · https://doi.org/10.1172/jci231

• Localization of MIWC and GLIP water channel homologs in neuromuscular, epithelial and glandular tissues

  Journal of Cell Science · 1995 · https://doi.org/10.1242/jcs.108.9.2993

• Molecular cloning of a mercurial-insensitive water channel expressed in selected water-transporting tissues.

  Journal of Biological Chemistry · 1994 · https://doi.org/10.1016/s0021-9258(17)37486-0

Current projects

No projects listed.