Eric J. Huang

Research interests

Publications

• Comorbid neuropathological diagnoses in early versus late-onset Alzheimer’s disease

  Brain · 2021 · https://doi.org/10.1093/brain/awab099

• Outer Radial Glia-like Cancer Stem Cells Contribute to Heterogeneity of Glioblastoma

  Cell stem cell · 2020 · 10.1016/j.stem.2019.11.015

• Astrocyte layers in the mammalian cerebral cortex revealed by a single-cell in situ transcriptomic map

  Nature Neuroscience · 2020 · https://doi.org/10.1038/s41593-020-0602-1

• The LC3-conjugation machinery specifies the loading of RNA-binding proteins into extracellular vesicles

  Nature Cell Biology · 2020 · 10.1038/s41556-019-0450-y

• Human hippocampal neurogenesis drops sharply in children to undetectable levels in adults

  Nature · 2018 · https://doi.org/10.1038/nature25975

• Multisite study of the relationships between antemortem [ 11 C]PIB‐PET Centiloid values and postmortem measures of Alzheimer's disease neuropathology

  Alzheimer s & Dementia · 2018 · https://doi.org/10.1016/j.jalz.2018.09.001

• Clinicopathological correlations in behavioural variant frontotemporal dementia

  Brain · 2017 · https://doi.org/10.1093/brain/awx254

• Self-Organized Cerebral Organoids with Human-Specific Features Predict Effective Drugs to Combat Zika Virus Infection

  Cell Reports · 2017 · 10.1016/j.celrep.2017.09.047

• Typical and atypical pathology in primary progressive aphasia variants

  Annals of Neurology · 2017 · https://doi.org/10.1002/ana.24885

• Extensive migration of young neurons into the infant human frontal lobe

  Science · 2016 · 10.1126/science.aaf7073

• Progranulin Deficiency Promotes Circuit-Specific Synaptic Pruning by Microglia via Complement Activation

  Cell · 2016 · https://doi.org/10.1016/j.cell.2016.04.001

• Existing Pittsburgh Compound-B positron emission tomography thresholds are too high: statistical and pathological evaluation

  Brain · 2015 · 10.1093/brain/awv112

• The behavioural/dysexecutive variant of Alzheimer’s disease: clinical, neuroimaging and pathological features

  Brain · 2015 · 10.1093/brain/awv191

• Interaction of FUS and HDAC1 regulates DNA damage response and repair in neurons

  Nature Neuroscience · 2013 · 10.1038/nn.3514

• A Dramatic Increase of C1q Protein in the CNS during Normal Aging

  Journal of Neuroscience · 2013 · https://doi.org/10.1523/jneurosci.1333-13.2013

• Progranulin deficiency promotes neuroinflammation and neuron loss following toxin-induced injury

  Journal of Clinical Investigation · 2012 · 10.1172/jci63113

• Amyloid vs FDG-PET in the differential diagnosis of AD and FTLD

  Neurology · 2011 · https://doi.org/10.1212/wnl.0b013e31823b9c5e

• Corridors of migrating neurons in the human brain and their decline during infancy

  Nature · 2011 · https://doi.org/10.1038/nature10487

• Clinicopathological correlations in corticobasal degeneration

  Annals of Neurology · 2011 · 10.1002/ana.22424

• Axin2 as regulatory and therapeutic target in newborn brain injury and remyelination

  Nature Neuroscience · 2011 · 10.1038/nn.2855

• Acetylation of Tau Inhibits Its Degradation and Contributes to Tauopathy

  Neuron · 2010 · 10.1016/j.neuron.2010.08.044

• Trk Receptors: Roles in Neuronal Signal Transduction

  Annual Review of Biochemistry · 2003 · 10.1146/annurev.biochem.72.121801.161629

• Neurotrophins: Roles in Neuronal Development and Function

  Annual Review of Neuroscience · 2001 · 10.1146/annurev.neuro.24.1.677

• The kit -ligand (steel factor) and its receptor c-kit/W: pleiotropic roles in gametogenesis and melanogenesis

  Development · 1993 · 10.1242/dev.119.supplement.125

• Differential expression and processing of two cell associated forms of the kit-ligand: KL-1 and KL-2.

  Molecular Biology of the Cell · 1992 · 10.1091/mbc.3.3.349

• The hematopoietic growth factor KL is encoded by the SI locus and is the ligand of the c-kit receptor, the gene product of the W locus

  Cell · 1990 · 10.1016/0092-8674(90)90303-v

Current projects

No projects listed.