Michelle L. Hermiston

Research interests

Publications

• International expert consensus recommendations for the diagnosis and treatment of Langerhans cell histiocytosis in adults

  Blood · 2022 · 10.1182/blood.2021014343

• Children's Oncology Group Trial AALL1231: A Phase III Clinical Trial Testing Bortezomib in Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia and Lymphoma

  Journal of Clinical Oncology · 2022 · 10.1200/jco.21.02678

• Optimal fludarabine lymphodepletion is associated with improved outcomes after CAR T-cell therapy

  Blood Advances · 2021 · 10.1182/bloodadvances.2021006418

• T-cell activation profiles distinguish hemophagocytic lymphohistiocytosis and early sepsis

  Blood · 2020 · 10.1182/blood.2020009499

• Lymphoblastic lymphoma in children and adolescents: review of current challenges and future opportunities

  British Journal of Haematology · 2019 · 10.1111/bjh.15793

• Challenges in the diagnosis of hemophagocytic lymphohistiocytosis: Recommendations from the North American Consortium for Histiocytosis (NACHO)

  Pediatric Blood & Cancer · 2019 · 10.1002/pbc.27929

• Preclinical efficacy of daratumumab in T-cell acute lymphoblastic leukemia

  Blood · 2018 · 10.1182/blood-2017-07-794214

• Outcome of children with multiply relapsed B-cell acute lymphoblastic leukemia: a therapeutic advances in childhood leukemia & lymphoma study

  Leukemia · 2018 · 10.1038/s41375-018-0094-0

• JAK/STAT pathway inhibition overcomes IL7-induced glucocorticoid resistance in a subset of human T-cell acute lymphoblastic leukemias

  Leukemia · 2017 · 10.1038/leu.2017.136

• Efficacy of JAK/STAT pathway inhibition in murine xenograft models of early T-cell precursor (ETP) acute lymphoblastic leukemia

  Blood · 2015 · 10.1182/blood-2014-06-580480

• The genetic basis of early T-cell precursor acute lymphoblastic leukaemia

  Nature · 2012 · https://doi.org/10.1038/nature10725

• CD45, CD148, and Lyp/Pep: critical phosphatases regulating Src family kinase signaling networks in immune cells

  Immunological Reviews · 2009 · 10.1111/j.1600-065x.2008.00752.x

• PTPN22 Deficiency Cooperates with the CD45 E613R Allele to Break Tolerance on a Non-Autoimmune Background

  The Journal of Immunology · 2009 · 10.4049/jimmunol.0803317

• CD45: A Critical Regulator of Signaling Thresholds in Immune Cells

  Annual Review of Immunology · 2003 · https://doi.org/10.1146/annurev.immunol.21.120601.140946

• Reciprocal regulation of lymphocyte activation by tyrosine kinases and phosphatases

  Journal of Clinical Investigation · 2002 · 10.1172/jci14794

• Reciprocal regulation of lymphocyte activation by tyrosine kinases and phosphatases

  Journal of Clinical Investigation · 2002 · 10.1172/jci0214794

• Phenotype of mice lacking functional Deleted in colorectal cancer (Dec) gene

  Nature · 1997 · https://doi.org/10.1038/386796a0

• Forced expression of E-cadherin in the mouse intestinal epithelium slows cell migration and provides evidence for nonautonomous regulation of cell fate in a self-renewing system.

  Genes & Development · 1996 · 10.1101/gad.10.8.985

• Forced expression of the tumor suppressor adenomatosis polyposis coli protein induces disordered cell migration in the intestinal epithelium.

  Proceedings of the National Academy of Sciences · 1996 · 10.1073/pnas.93.18.9588

• In vivo analysis of cadherin function in the mouse intestinal epithelium: essential roles in adhesion, maintenance of differentiation, and regulation of programmed cell death.

  The Journal of Cell Biology · 1995 · 10.1083/jcb.129.2.489

• Inflammatory Bowel Disease and Adenomas in Mice Expressing a Dominant Negative N-Cadherin

  Science · 1995 · https://doi.org/10.1126/science.270.5239.1203

• Differentiation and self-renewal in the mouse gastrointestinal epithelium

  Current Opinion in Cell Biology · 1994 · 10.1016/0955-0674(94)90047-7

Current projects

No projects listed.