Bruce L. Miller

Research interests

Publications

• Plasma phosphorylated tau 217 and phosphorylated tau 181 as biomarkers in Alzheimer's disease and frontotemporal lobar degeneration: a retrospective diagnostic performance study

  The Lancet Neurology · 2021 · https://doi.org/10.1016/s1474-4422(21)00214-3

• A multicentre validation study of the diagnostic value of plasma neurofilament light

  Nature Communications · 2021 · https://doi.org/10.1038/s41467-021-23620-z

• Tau PTM Profiles Identify Patient Heterogeneity and Stages of Alzheimer’s Disease

  Cell · 2020 · https://doi.org/10.1016/j.cell.2020.10.029

• Diagnostic value of plasma phosphorylated tau181 in Alzheimer’s disease and frontotemporal lobar degeneration

  Nature Medicine · 2020 · https://doi.org/10.1038/s41591-020-0762-2

• ApoE4 markedly exacerbates tau-mediated neurodegeneration in a mouse model of tauopathy

  Nature · 2017 · https://doi.org/10.1038/nature24016

• Tau PET patterns mirror clinical and neuroanatomical variability in Alzheimer’s disease

  Brain · 2016 · 10.1093/brain/aww027

• Frontotemporal dementia

  The Lancet · 2015 · 10.1016/s0140-6736(15)00461-4

• Prevalence of Amyloid PET Positivity in Dementia Syndromes

  JAMA · 2015 · 10.1001/jama.2015.4669

• Identification of preclinical Alzheimer's disease by a profile of pathogenic proteins in neurally derived blood exosomes: A case‐control study

  Alzheimer s & Dementia · 2014 · 10.1016/j.jalz.2014.06.008

• Criteria for the diagnosis of corticobasal degeneration

  Neurology · 2013 · 10.1212/wnl.0b013e31827f0fd1

• Expanded GGGGCC Hexanucleotide Repeat in Noncoding Region of C9ORF72 Causes Chromosome 9p-Linked FTD and ALS

  Neuron · 2011 · https://doi.org/10.1016/j.neuron.2011.09.011

• Sensitivity of revised diagnostic criteria for the behavioural variant of frontotemporal dementia

  Brain · 2011 · https://doi.org/10.1093/brain/awr179

• Classification of primary progressive aphasia and its variants

  Neurology · 2011 · https://doi.org/10.1212/wnl.0b013e31821103e6

• Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease

  Nature Genetics · 2011 · 10.1038/ng.801

• Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions

  Nature Genetics · 2010 · 10.1038/ng.536

• Divergent network connectivity changes in behavioural variant frontotemporal dementia and Alzheimer’s disease

  Brain · 2010 · 10.1093/brain/awq075

• Neurodegenerative Diseases Target Large-Scale Human Brain Networks

  Neuron · 2009 · 10.1016/j.neuron.2009.03.024

• Classification and prediction of clinical Alzheimer's diagnosis based on plasma signaling proteins

  Nature Medicine · 2007 · 10.1038/nm1653

• The pyroptosome: a supramolecular assembly of ASC dimers mediating inflammatory cell death via caspase-1 activation

  Cell Death and Differentiation · 2007 · 10.1038/sj.cdd.4402194

• Ubiquitinated TDP-43 in Frontotemporal Lobar Degeneration and Amyotrophic Lateral Sclerosis

  Science · 2006 · https://doi.org/10.1126/science.1134108

• Genomic sequence of the pathogenic and allergenic filamentous fungus Aspergillus fumigatus

  Nature · 2005 · 10.1038/nature04332

• Sequencing of Aspergillus nidulans and comparative analysis with A. fumigatus and A. oryzae

  Nature · 2005 · 10.1038/nature04341

• Cognition and anatomy in three variants of primary progressive aphasia

  Annals of Neurology · 2004 · 10.1002/ana.10825

• Practice parameter: Diagnosis of dementia (an evidence-based review)

  Neurology · 2001 · 10.1212/wnl.56.9.1143

• Frontotemporal lobar degeneration

  Neurology · 1998 · https://doi.org/10.1212/wnl.51.6.1546

• Consensus guidelines for the clinical and pathologic diagnosis of dementia with Lewy bodies (DLB)

  Neurology · 1996 · 10.1212/wnl.47.5.1113

Current projects

No projects listed.