Jan H.J. Hoeijmakers

Researcher Next ID · RN-026376

Researcher · Biochemistry, Genetics and Molecular Biology

Cologne, Netherlands

Not currently recruitingFunding unknown

Research interests

Biochemistry, Genetics and Molecular Biology

DNA Repair Mechanisms

CRISPR and Genetic Engineering

Carcinogens and Genotoxicity Assessment

Genomics and Chromatin Dynamics

Genetics, Aging, and Longevity in Model Organisms

Targeted Apoptosis of Senescent Cells Restores Tissue Homeostasis in Response to Chemotoxicity and Aging
Cell · 2017 · https://doi.org/10.1016/j.cell.2017.02.031
MARK-AGE biomarkers of ageing
Mechanisms of Ageing and Development · 2015 · https://doi.org/10.1016/j.mad.2015.03.006
An Essential Role for Senescent Cells in Optimal Wound Healing through Secretion of PDGF-AA
Developmental Cell · 2014 · https://doi.org/10.1016/j.devcel.2014.11.012
Nucleotide Excision DNA Repair Is Associated With Age-Related Vascular Dysfunction
Circulation · 2012 · https://doi.org/10.1161/circulationaha.112.104380
DNA Damage, Aging, and Cancer
New England Journal of Medicine · 2009 · https://doi.org/10.1056/nejmra0804615
Deficiencies in DNA damage repair limit the function of haematopoietic stem cells with age
Nature · 2007 · https://doi.org/10.1038/nature05862
Genome maintenance mechanisms for preventing cancer
Nature · 2001 · https://doi.org/10.1038/35077232
A mutation in the XPB/ERCC3 DNA repair transcription gene, associated with trichothiodystrophy.
PubMed · 1997
The XPB and XPD DNA helicases are components of the p53-mediated apoptosis pathway.
Genes & Development · 1996 · https://doi.org/10.1101/gad.10.10.1219
p53 modulation of TFIIH–associated nucleotide excision repair activity
Nature Genetics · 1995 · https://doi.org/10.1038/ng0695-188

No projects listed.