Graham Robertson

Research interests

Publications

• An immune-sympathetic neuron communication axis guides adipose tissue browning in cancer-associated cachexia

  Proceedings of the National Academy of Sciences · 2022 · 10.1073/pnas.2112840119

• Microglia integration into human midbrain organoids leads to increased neuronal maturation and functionality

  Glia · 2022 · https://doi.org/10.1002/glia.24167

• Vitamin D in Vascular Calcification: A Double-Edged Sword?

  Nutrients · 2018 · 10.3390/nu10050652

• Neuronal networks provide rapid neuroprotection against spreading toxicity

  Scientific Reports · 2016 · https://doi.org/10.1038/srep33746

• Lipolytic and thermogenic depletion of adipose tissue in cancer cachexia

  Seminars in Cell and Developmental Biology · 2015 · 10.1016/j.semcdb.2015.10.039

• A Switch from White to Brown Fat Increases Energy Expenditure in Cancer-Associated Cachexia

  Cell Metabolism · 2014 · https://doi.org/10.1016/j.cmet.2014.06.011

• Depletion of White Adipose Tissue in Cancer Cachexia Syndrome Is Associated with Inflammatory Signaling and Disrupted Circadian Regulation

  PLoS ONE · 2014 · 10.1371/journal.pone.0092966

• Activation of Thermogenesis in Brown Adipose Tissue and Dysregulated Lipid Metabolism Associated with Cancer Cachexia in Mice

  Cancer Research · 2012 · 10.1158/0008-5472.can-11-3536

• Src tyrosine kinase phosphorylation of nuclear receptor HNF4α correlates with isoform-specific loss of HNF4α in human colon cancer

  Proceedings of the National Academy of Sciences · 2012 · 10.1073/pnas.1106799109

• Cancer cachexia: malignant inflammation, tumorkines, and metabolic mayhem

  Trends in Endocrinology and Metabolism · 2012 · 10.1016/j.tem.2012.10.006

• Inflammation and CYP3A4-mediated drug metabolism in advanced cancer: impact and implications for chemotherapeutic drug dosing

  Expert Opinion on Drug Metabolism & Toxicology · 2008 · 10.1517/17425255.4.2.137

• Regulation of Drug-Metabolizing Enzymes and Transporters in Infection, Inflammation, and Cancer

  Drug Metabolism and Disposition · 2008 · 10.1124/dmd.107.018747

• Feed-forward Regulation of Bile Acid Detoxification by CYP3A4

  Journal of Biological Chemistry · 2004 · 10.1074/jbc.m310258200

• Hepatic microvascular dysfunction during evolution of dietary steatohepatitis in mice

  Hepatology · 2004 · https://doi.org/10.1002/hep.20302

• Administration of the potent PPARα agonist, Wy-14,643, reverses nutritional fibrosis and steatohepatitis in mice

  Hepatology · 2004 · 10.1002/hep.20170

• Central Role of Pparα–Dependent Hepatic Lipid Turnover in Dietary Steatohepatitis in Mice

  Hepatology · 2003 · 10.1053/jhep.2003.50307

• Transcriptional Regulation of the Human CYP3A4Gene by the Constitutive Androstane Receptor

  Molecular Pharmacology · 2002 · https://doi.org/10.1124/mol.62.2.359

• Leptin is essential for the hepatic fibrogenic response to chronic liver injury

  Journal of Hepatology · 2002 · 10.1016/s0168-8278(02)00102-2

• II. CytochromeP-450 enzymes and oxidative stress

  American Journal of Physiology-Gastrointestinal and Liver Physiology · 2001 · 10.1152/ajpgi.2001.281.5.g1135

• CYP2E1 and CYP4A as microsomal catalysts of lipid peroxides in murine nonalcoholic steatohepatitis

  Journal of Clinical Investigation · 2000 · https://doi.org/10.1172/jci8814

• Altered Expression of HepaticCYP2E1andCYP4Ain Obese, Diabeticob/obMice, andfa/faZucker Rats

  Biochemical and Biophysical Research Communications · 1999 · 10.1006/bbrc.1999.0202

• Identification and Nucleotide Sequence of a Gene in Equine Herpesvirus 1 Analogous to the Herpes Simplex Virus Gene Encoding the Major Envelope Glycoprotein gB

  Journal of General Virology · 1989 · 10.1099/0022-1317-70-2-383

• DIFFERENTIATION OF SUB‐TYPES OF EQUINE HERPESVIRUS I BY RESTRICTION ENDONUCLEASE ANALYSIS

  Australian Veterinary Journal · 1981 · 10.1111/j.1751-0813.1981.tb00495.x

• Analysis of the Genome of Equine Herpesvirus Type 1: Arrangement of Cleavage Sites for Restriction Endonucleases EcoRI, BglII and BamHI

  Journal of General Virology · 1981 · 10.1099/0022-1317-57-2-307

Current projects

No projects listed.