Bing Su

Research interests

Publications

• Single-cell and spatial analysis reveal interaction of FAP+ fibroblasts and SPP1+ macrophages in colorectal cancer

  Nature Communications · 2022 · https://doi.org/10.1038/s41467-022-29366-6

• cGAS-STING–mediated DNA sensing maintains CD8 + T cell stemness and promotes antitumor T cell therapy

  Science Translational Medicine · 2020 · 10.1126/scitranslmed.aay9013

• Paracrine orchestration of intestinal tumorigenesis by a mesenchymal niche

  Nature · 2020 · 10.1038/s41586-020-2166-3

• Fate Mapping via Ms4a3-Expression History Traces Monocyte-Derived Cells

  Cell · 2019 · https://doi.org/10.1016/j.cell.2019.08.009

• m6A mRNA methylation sustains Treg suppressive functions

  Cell Research · 2018 · 10.1038/cr.2018.7

• A novel IL-17 signaling pathway controlling keratinocyte proliferation and tumorigenesis via the TRAF4–ERK5 axis

  The Journal of Experimental Medicine · 2015 · 10.1084/jem.20150204

• PtdIns(3,4,5) P 3-Dependent Activation of the mTORC2 Kinase Complex

  Cancer Discovery · 2015 · 10.1158/2159-8290.cd-15-0460

• NF-κB-induced microRNA-31 promotes epidermal hyperplasia by repressing protein phosphatase 6 in psoriasis

  Nature Communications · 2015 · 10.1038/ncomms8652

• Sin1 phosphorylation impairs mTORC2 complex integrity and inhibits downstream Akt signalling to suppress tumorigenesis

  Nature Cell Biology · 2013 · 10.1038/ncb2860

• mTORC2 can associate with ribosomes to promote cotranslational phosphorylation and stability of nascent Akt polypeptide

  The EMBO Journal · 2010 · 10.1038/emboj.2010.271

• Genetic Variations in Tibetan Populations and High-Altitude Adaptation at the Himalayas

  Molecular Biology and Evolution · 2010 · 10.1093/molbev/msq290

• The mammalian target of rapamycin complex 2 controls folding and stability of Akt and protein kinase C

  The EMBO Journal · 2008 · 10.1038/emboj.2008.120

• Plasmacytoid dendritic cells sense self-DNA coupled with antimicrobial peptide

  Nature · 2007 · https://doi.org/10.1038/nature06116

• SIN1/MIP1 Maintains rictor-mTOR Complex Integrity and Regulates Akt Phosphorylation and Substrate Specificity

  Cell · 2006 · https://doi.org/10.1016/j.cell.2006.08.033

• Differential regulation of interleukin 1 receptor and Toll-like receptor signaling by MEKK3

  Nature Immunology · 2003 · 10.1038/ni1014

• The essential role of MEKK3 in TNF-induced NF-κB activation

  Nature Immunology · 2001 · 10.1038/89769

• Mekk3 is essential for early embryonic cardiovascular development

  Nature Genetics · 2000 · 10.1038/73550

• MEK kinase 1 is critically required for c-Jun N-terminal kinase activation by proinflammatory stimuli and growth factor-induced cell migration

  Proceedings of the National Academy of Sciences · 2000 · 10.1073/pnas.97.10.5243

• Cardiac Hypertrophy Induced by Mitogen-activated Protein Kinase Kinase 7, a Specific Activator for c-Jun NH2-terminal Kinase in Ventricular Muscle Cells

  Journal of Biological Chemistry · 1998 · 10.1074/jbc.273.10.5423

• The tumor promoter arsenite stimulates AP‐1 activity by inhibiting a JNK phosphatase.

  The EMBO Journal · 1996 · 10.1002/j.1460-2075.1996.tb01017.x

• Mitogen-activated protein kinase cascades and regulation of gene expression

  Current Opinion in Immunology · 1996 · 10.1016/s0952-7915(96)80131-2

• The Ras-JNK Pathway Is Involved in Shear-Induced Gene Expression

  Molecular and Cellular Biology · 1996 · 10.1128/mcb.16.11.5947

• JNK2 contains a specificity-determining region responsible for efficient c-Jun binding and phosphorylation.

  Genes & Development · 1994 · 10.1101/gad.8.24.2996

• JNK1: A protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain

  Cell · 1994 · 10.1016/0092-8674(94)90380-8

• JNK is involved in signal integration during costimulation of T lymphocytes

  Cell · 1994 · https://doi.org/10.1016/0092-8674(94)90056-6

Current projects

No projects listed.